KEGG   PATHWAY: bmal00630
Entry
bmal00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia mallei 23344
Class
Metabolism; Carbohydrate metabolism
Pathway map
bmal00630  Glyoxylate and dicarboxylate metabolism
bmal00630

Module
bmal_M00012  Glyoxylate cycle [PATH:bmal00630]
bmal_M00621  Glycine cleavage system [PATH:bmal00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia mallei 23344 [GN:bmal]
Gene
DM55_237  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
DM55_3989  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DM55_2777  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
DM55_241  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
DM55_3326  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DM55_3319  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
DM55_1508  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
DM55_3330  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
DM55_605  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM55_73  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM55_1175  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM55_3164  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM55_3169  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
DM55_3548  phbB; acetoacetyl-CoA reductase family protein [KO:K00023] [EC:1.1.1.36]
DM55_3168  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
DM55_1372  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
DM55_1373  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
DM55_1374  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
DM55_4290  katB; catalase [KO:K03781] [EC:1.11.1.6]
DM55_1901  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
DM55_4115  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
DM55_2214  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
DM55_2019  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
DM55_2380  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
DM55_4054  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
DM55_1124  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
DM55_1126  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
DM55_3789  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM55_2235  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM55_3094  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DM55_1125  gcvH; glycine cleavage system H protein [KO:K02437]
DM55_100  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
DM55_3688  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
DM55_640  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DM55_4258  oxdD; oxalate decarboxylase oxdD [KO:K01569] [EC:4.1.1.2]
DM55_3262  Tat (twin-arginine translocation) pathway signal sequence domain protein [KO:K00123] [EC:1.17.1.9]
DM55_1815  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
DM55_1816  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
DM55_3259  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
DM55_1817  thioredoxin-like [2Fe-2S] ferredoxin family protein [KO:K00127]
DM55_3258  formate dehydrogenase, gamma subunit [KO:K00127]
DM55_2816  alpha/beta hydrolase fold family protein [KO:K01432] [EC:3.5.1.9]
DM55_1747  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
DM55_4065  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DM55_1098  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DM55_2017  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bmal00010  Glycolysis / Gluconeogenesis
bmal00020  Citrate cycle (TCA cycle)
bmal00030  Pentose phosphate pathway
bmal00053  Ascorbate and aldarate metabolism
bmal00071  Fatty acid degradation
bmal00230  Purine metabolism
bmal00250  Alanine, aspartate and glutamate metabolism
bmal00260  Glycine, serine and threonine metabolism
bmal00620  Pyruvate metabolism
bmal00710  Carbon fixation in photosynthetic organisms
bmal00750  Vitamin B6 metabolism
bmal00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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