KEGG   PATHWAY: bpd00630
Entry
bpd00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia pseudomallei 668
Class
Metabolism; Carbohydrate metabolism
Pathway map
bpd00630  Glyoxylate and dicarboxylate metabolism
bpd00630

Module
bpd_M00012  Glyoxylate cycle [PATH:bpd00630]
bpd_M00621  Glycine cleavage system [PATH:bpd00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia pseudomallei 668 [GN:bpd]
Gene
BURPS668_2470  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BURPS668_A0628  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BURPS668_1509  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
BURPS668_A0919  AMP-binding enzyme [KO:K01895] [EC:6.2.1.1]
BURPS668_2475  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BURPS668_A2474  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BURPS668_A2467  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BURPS668_0942  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
BURPS668_A2478  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BURPS668_2160  bktB; acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
BURPS668_2165  phbA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BURPS668_0396  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BURPS668_2292  acetyl-CoA acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BURPS668_0074  acetyl-CoA acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BURPS668_A2744  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BURPS668_2164  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BURPS668_3296  putative glycolate oxidase, subunit GlcD [KO:K00104] [EC:1.1.99.14]
BURPS668_3297  glcE; glycolate oxidase, GlcE subunit [KO:K11472] [EC:1.1.99.14]
BURPS668_3298  glcF; glycolate oxidase, iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
BURPS668_A1461  katB; catalase [KO:K03781] [EC:1.11.1.6]
BURPS668_A3115  catalase [KO:K03781] [EC:1.11.1.6]
BURPS668_0085  putative chaperone protein [KO:K03781] [EC:1.11.1.6]
BURPS668_0354  ghrA; glyoxylate reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BURPS668_2094  tkrA; gluconate 2-dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BURPS668_2809  glyoxylate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BURPS668_2800  hydrolase, haloacid dehalogenase-like family [KO:K01091] [EC:3.1.3.18]
BURPS668_3555  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
BURPS668_A0728  glutamine synthetase catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BURPS668_2654  glutamine synthetase catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BURPS668_2634  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BURPS668_A0828  glyA_2; glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BURPS668_3196  glyA_1; glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
BURPS668_3929  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BURPS668_3926  gcvT; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
BURPS668_1752  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BURPS668_2610  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BURPS668_A3190  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BURPS668_3927  gcvH; glycine cleavage system H protein [KO:K02437]
BURPS668_2259  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BURPS668_2260  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BURPS668_2261  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BURPS668_A0262  glxK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
BURPS668_2327  glxK; glycerate kinase [KO:K00865] [EC:2.7.1.165]
BURPS668_A0015  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BURPS668_3406  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BURPS668_A1413  oxdD; oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
BURPS668_2903  fdsD; formate dehydrogenase, NAD-dependent, delta subunit [KO:K00126] [EC:1.17.1.9]
BURPS668_2902  fdsA; formate dehydrogenase, NAD-dependent, alpha subunit [KO:K00123] [EC:1.17.1.9]
BURPS668_A2396  fdoG; formate dehydrogenase-O, alpha subunit, selenocysteine-containing [KO:K00123] [EC:1.17.1.9]
BURPS668_2901  fdsB; NAD-dependent formate dehydrogenase, beta subunit [KO:K00124]
BURPS668_A2395  fdoH; formate dehydrogenase, beta subunit [KO:K00124]
BURPS668_2900  formate dehydrogenase family protein [KO:K00127]
BURPS668_A2394  fdoI; formate dehydrogenase, gamma subunit [KO:K00127]
BURPS668_1574  conserved hypothetical protein [KO:K01432] [EC:3.5.1.9]
BURPS668_0894  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
BURPS668_A0839  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BURPS668_0591  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BURPS668_2660  hutG; N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bpd00010  Glycolysis / Gluconeogenesis
bpd00020  Citrate cycle (TCA cycle)
bpd00030  Pentose phosphate pathway
bpd00053  Ascorbate and aldarate metabolism
bpd00071  Fatty acid degradation
bpd00230  Purine metabolism
bpd00250  Alanine, aspartate and glutamate metabolism
bpd00260  Glycine, serine and threonine metabolism
bpd00620  Pyruvate metabolism
bpd00710  Carbon fixation in photosynthetic organisms
bpd00750  Vitamin B6 metabolism
bpd00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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