KEGG   PATHWAY: brp04141
Entry
brp04141                    Pathway                                
Name
Protein processing in endoplasmic reticulum - Brassica rapa (field mustard)
Description
The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.
Class
Genetic Information Processing; Folding, sorting and degradation
Pathway map
brp04141  Protein processing in endoplasmic reticulum
brp04141

Other DBs
GO: 0030433 0034976
Organism
Brassica rapa (field mustard) [GN:brp]
Gene
103867471  protein transport protein Sec61 subunit alpha [KO:K10956]
103828373  preprotein translocase subunit SCY1, chloroplastic isoform X2 [KO:K10956]
103840500  protein transport protein Sec61 subunit alpha [KO:K10956]
103830364  protein transport protein Sec61 subunit alpha [KO:K10956]
103857525  protein transport protein Sec61 subunit alpha [KO:K10956]
103865320  protein transport protein Sec61 subunit alpha [KO:K10956]
103845464  protein transport protein Sec61 subunit beta [KO:K09481]
103866860  protein transport protein Sec61 subunit beta [KO:K09481]
103858150  protein transport protein Sec61 subunit beta [KO:K09481]
103866191  protein transport protein Sec61 subunit beta [KO:K09481]
103856559  protein transport protein Sec61 subunit beta [KO:K09481]
103862711  protein transport protein Sec61 subunit gamma-1 [KO:K07342]
103852189  protein transport protein Sec61 subunit gamma-1 [KO:K07342]
103873129  protein transport protein Sec61 subunit gamma-3 [KO:K07342]
103861513  protein transport protein Sec61 subunit gamma-1 [KO:K07342]
103858453  protein transport protein Sec61 subunit gamma-1 [KO:K07342]
103869217  uncharacterized protein LOC103869217 isoform X1 [KO:K12275]
103859879  uncharacterized protein LOC103859879 isoform X1 [KO:K12275]
103835563  uncharacterized protein LOC103835563 isoform X1 [KO:K12275]
103858834  dnaJ protein ERDJ2B [KO:K09540]
103830407  dnaJ protein ERDJ2A [KO:K09540]
103854046  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1B [KO:K12666]
103832096  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A [KO:K12666]
103827559  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1B [KO:K12666]
103858773  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 [KO:K12667]
103861216  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 [KO:K12667]
103840178  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [KO:K12668]
103868894  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [KO:K12668]
103837704  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [KO:K12670]
103829578  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [KO:K12670]
103840023  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B isoform X2 [KO:K07151] [EC:2.4.99.18]
103856390  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [KO:K07151] [EC:2.4.99.18]
103845732  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [KO:K07151] [EC:2.4.99.18]
103831105  probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B [KO:K19478]
103831124  probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B [KO:K19478]
103836227  probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B [KO:K19478]
103861913  oligosaccharyltransferase complex subunit ostc-like [KO:K26501]
103853218  oligosaccharyltransferase complex subunit ostc [KO:K26501]
103861900  transmembrane protein 258 [KO:K26502]
103853335  transmembrane protein 258 [KO:K26502]
103831024  mannosyl-oligosaccharide glucosidase GCS1 [KO:K01228] [EC:3.2.1.106]
103829083  alpha-glucosidase 2 isoform X3 [KO:K01228] [EC:3.2.1.106]
103869325  LOW QUALITY PROTEIN: heat shock 70 kDa protein 17 [KO:K09486]
103860878  heat shock 70 kDa protein 17 [KO:K09486]
103843363  probable mediator of RNA polymerase II transcription subunit 37b isoform X2 [KO:K09490] [EC:3.6.4.10]
103857349  mediator of RNA polymerase II transcription subunit 37f [KO:K09490] [EC:3.6.4.10]
103850248  mediator of RNA polymerase II transcription subunit 37f [KO:K09490] [EC:3.6.4.10]
103828629  mediator of RNA polymerase II transcription subunit 37f [KO:K09490] [EC:3.6.4.10]
103857669  mediator of RNA polymerase II transcription subunit 37f-like [KO:K09490] [EC:3.6.4.10]
103842067  dnaJ protein ERDJ3B [KO:K09517]
103862783  dnaJ protein ERDJ3B [KO:K09517]
103830360  dnaJ protein ERDJ3B-like [KO:K09517]
103847406  dnaJ protein P58IPK homolog [KO:K09523]
103849092  heat shock protein 90-6, mitochondrial isoform X1 [KO:K09487]
103861819  endoplasmin homolog [KO:K09487]
103870635  heat shock protein 90-6, mitochondrial [KO:K09487]
103875375  heat shock protein 90-5, chloroplastic [KO:K09487]
103839376  heat shock protein 90-5, chloroplastic isoform X1 [KO:K09487]
103834913  endoplasmin homolog [KO:K09487]
103837502  probable glucan 1,3-alpha-glucosidase [KO:K05546] [EC:3.2.1.207]
103873801  probable glucan 1,3-alpha-glucosidase [KO:K05546] [EC:3.2.1.207]
103856932  glucosidase 2 subunit beta isoform X1 [KO:K08288]
103845078  glucosidase 2 subunit beta isoform X1 [KO:K08288]
103854961  calnexin homolog 1 [KO:K08054]
103873468  calnexin homolog 1 [KO:K08054]
103837395  CAX1; calnexin homolog 1 [KO:K08054]
103847648  calreticulin-1 [KO:K08057]
103832359  V-type proton ATPase catalytic subunit A isoform X1 [KO:K08057]
103836348  calreticulin-2 [KO:K08057]
103838690  calreticulin-1 [KO:K08057]
103836390  calreticulin-3 isoform X2 [KO:K08057]
103843398  calreticulin-3 [KO:K08057]
103871649  calreticulin-2 [KO:K08057]
103832838  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1 [KO:K01230] [EC:3.2.1.113]
103859891  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS2 [KO:K01230] [EC:3.2.1.113]
103869203  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS2 [KO:K01230] [EC:3.2.1.113]
103871276  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1 [KO:K01230] [EC:3.2.1.113]
103835247  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS3 [KO:K23741] [EC:3.2.1.209]
103840441  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS3 [KO:K23741] [EC:3.2.1.209]
103841155  SEC12-like protein 1 [KO:K14003]
103854073  SEC12-like protein 2 isoform X2 [KO:K14003]
103827587  SEC12-like protein 2 isoform X1 [KO:K14003]
103863479  SEC12-like protein 1 [KO:K14003]
103847650  GTP-binding protein SAR1B-like [KO:K07953] [EC:3.6.5.-]
103836350  GTP-binding protein SAR1B [KO:K07953] [EC:3.6.5.-]
103838691  GTP-binding protein SAR1B [KO:K07953] [EC:3.6.5.-]
103836780  GTP-binding protein SAR1A [KO:K07953] [EC:3.6.5.-]
103871647  GTP-binding protein SAR1B [KO:K07953] [EC:3.6.5.-]
103858778  GTP-binding protein SAR1A [KO:K07953] [EC:3.6.5.-]
103867988  protein transport protein SEC13 homolog B [KO:K14004]
103870972  protein transport protein SEC13 homolog A [KO:K14004]
103857287  protein transport protein SEC13 homolog B [KO:K14004]
103865005  protein transport protein SEC13 homolog B [KO:K14004]
103835882  LOW QUALITY PROTEIN: protein transport protein SEC31 homolog A [KO:K14005]
103830389  protein transport protein SEC31 homolog B [KO:K14005]
103842135  LOW QUALITY PROTEIN: protein transport protein SEC31 homolog B [KO:K14005]
103836527  protein transport protein SEC23 [KO:K14006]
103842509  protein transport protein SEC23 [KO:K14006]
103827962  protein transport protein SEC23 [KO:K14006]
103863558  protein transport protein SEC23 [KO:K14006]
103835190  protein transport protein SEC23-like [KO:K14006]
103870702  protein transport protein Sec24-like At3g07100 [KO:K14007]
103848077  protein transport protein Sec24-like CEF [KO:K14007]
103849496  protein transport protein Sec24-like At3g07100 [KO:K14007]
103850674  protein transport protein Sec24-like At4g32640 [KO:K14007]
103859201  protein transport protein Sec24-like At3g07100 [KO:K14007]
103831647  UDP-glucose:glycoprotein glucosyltransferase isoform X2 [KO:K11718] [EC:2.4.1.-]
103839033  alpha-mannosidase I MNS5 [KO:K10084]
103848826  alpha-mannosidase I MNS4 [KO:K10085]
103845478  protein disulfide isomerase-like 1-4 [KO:K09580] [EC:5.3.4.1]
103853076  protein disulfide isomerase-like 1-2 [KO:K09580] [EC:5.3.4.1]
103873019  protein disulfide isomerase-like 1-1 [KO:K09580] [EC:5.3.4.1]
103832802  protein disulfide isomerase-like 1-5 [KO:K09580] [EC:5.3.4.1]
103829367  protein disulfide isomerase-like 1-1 [KO:K09580] [EC:5.3.4.1]
103841408  protein disulfide isomerase-like 1-3 [KO:K09580] [EC:5.3.4.1]
103832197  protein disulfide isomerase-like 1-2 [KO:K09580] [EC:5.3.4.1]
103835729  protein disulfide isomerase-like 1-1 [KO:K09580] [EC:5.3.4.1]
103871222  protein disulfide isomerase-like 1-5 [KO:K09580] [EC:5.3.4.1]
103851496  protein disulfide isomerase-like 1-4 [KO:K09580] [EC:5.3.4.1]
103868815  protein disulfide-isomerase 5-2 [KO:K09580] [EC:5.3.4.1]
103867595  protein disulfide-isomerase 2-3 [KO:K09584] [EC:5.3.4.1]
103866377  protein disulfide-isomerase like 2-1 [KO:K09584] [EC:5.3.4.1]
103844188  protein disulfide-isomerase like 2-2 [KO:K09584] [EC:5.3.4.1]
103858248  protein disulfide-isomerase like 2-1 isoform X2 [KO:K09584] [EC:5.3.4.1]
103831735  endoplasmic reticulum oxidoreductin-1 [KO:K10950] [EC:1.8.4.-]
103867067  endoplasmic reticulum oxidoreductin-2 [KO:K10950] [EC:1.8.4.-]
103867521  protein OS-9 homolog [KO:K10088]
103846035  translocon-associated protein subunit alpha isoform X1 [KO:K13249]
103842553  translocon-associated protein subunit alpha [KO:K13249]
103864251  translocon-associated protein subunit alpha isoform X2 [KO:K13249]
103846518  translocon-associated protein subunit beta [KO:K13250]
103850914  translocon-associated protein subunit beta [KO:K13250]
103854291  uncharacterized protein LOC103854291 [KO:K13250]
103856052  translocon-associated protein subunit beta [KO:K13250]
103874978  uncharacterized protein LOC103874978 [KO:K14009]
103843216  uncharacterized protein LOC103843216 [KO:K14009]
103854553  uncharacterized protein LOC103854553 [KO:K14009]
103869321  uncharacterized protein LOC103869321 [KO:K14009]
103859481  derlin-2.1 [KO:K13989]
103853697  derlin-1 [KO:K13989]
103834220  derlin-2.1 [KO:K13989]
103839809  derlin-2.2 [KO:K13989]
103862147  derlin-1 [KO:K13989]
103844206  chromatin assembly factor 1 subunit A isoform X4 [KO:K24348]
103866054  plant UBX domain-containing protein 11 isoform X1 [KO:K24348]
103836551  translation initiation factor IF-2-like isoform X1 [KO:K24348]
103827566  plant UBX domain-containing protein 2 [KO:K14011]
103859821  plant UBX domain-containing protein 3 [KO:K14012]
103833508  plant UBX domain-containing protein 5 [KO:K14012]
103839847  plant UBX domain-containing protein 4 [KO:K14012]
103864368  plant UBX domain-containing protein 5-like [KO:K14012]
103858648  plant UBX domain-containing protein 4 [KO:K14012]
103864367  plant UBX domain-containing protein 5-like [KO:K14012]
103864366  plant UBX domain-containing protein 5-like [KO:K14012]
103864301  plant UBX domain-containing protein 5-like [KO:K14012]
103829916  cell division control protein 48 homolog D [KO:K13525]
103855479  cell division control protein 48 homolog E [KO:K13525]
103847873  cell division control protein 48 homolog A [KO:K13525]
103859279  cell division control protein 48 homolog A [KO:K13525]
103870514  cell division control protein 48 homolog A [KO:K13525]
103862741  NPL4-like protein 1 [KO:K14015]
103842542  ubiquitin recognition factor in ER-associated degradation protein 1 isoform X1 [KO:K14016]
103864264  ubiquitin recognition factor in ER-associated degradation protein 1 [KO:K14016]
103864938  ubiquitin fusion degradation protein 1 homolog [KO:K14016]
103834915  heat shock 70 kDa protein 6, chloroplastic-like [KO:K03283]
103861480  heat shock 70 kDa protein 6, chloroplastic [KO:K03283]
103828680  LOW QUALITY PROTEIN: probable mediator of RNA polymerase II transcription subunit 37e [KO:K03283]
103836006  heat shock 70 kDa protein 5 [KO:K03283]
103837399  probable mediator of RNA polymerase II transcription subunit 37e [KO:K03283]
103840633  probable mediator of RNA polymerase II transcription subunit 37e [KO:K03283]
103847444  probable mediator of RNA polymerase II transcription subunit 37e [KO:K03283]
103847447  probable mediator of RNA polymerase II transcription subunit 37e [KO:K03283]
103845440  probable mediator of RNA polymerase II transcription subunit 37c [KO:K03283]
103861962  heat shock 70 kDa protein 6, chloroplastic [KO:K03283]
103859451  probable mediator of RNA polymerase II transcription subunit 37c [KO:K03283]
103872405  heat shock 70 kDa protein 5 [KO:K03283]
103860487  probable mediator of RNA polymerase II transcription subunit 37e [KO:K03283]
103845576  chaperone protein dnaJ 3 [KO:K09503]
103845575  chaperone protein dnaJ 3 [KO:K09503]
103856495  chaperone protein dnaJ 3 [KO:K09503]
103851419  chaperone protein dnaJ 3 [KO:K09503]
103875016  chaperone protein dnaJ 49 [KO:K09518]
103841641  chaperone protein dnaJ 49 [KO:K09518]
103846916  chaperone protein dnaJ 49 [KO:K09518]
103844749  LOW QUALITY PROTEIN: heat shock protein 90-1 [KO:K04079]
103851857  heat shock protein 90-2 [KO:K04079]
103856958  heat shock protein 90-2 [KO:K04079]
103856953  heat shock protein 90-2 [KO:K04079]
103856924  heat shock protein 90-2 [KO:K04079]
103851851  heat shock protein 90-2-like [KO:K04079]
103870549  uncharacterized protein LOC103870549 [KO:K09562]
103841303  hsp70-binding protein 1 [KO:K09562]
103859298  hsp70 nucleotide exchange factor fes1 [KO:K09562]
103841134  nucleotide exchange factor SIL1 [KO:K09562]
103846672  17.6 kDa class II heat shock protein [KO:K13993]
103868031  17.6 kDa class I heat shock protein 2 [KO:K13993]
103249161  17.6 kDa class II heat shock protein [KO:K13993]
103867529  heat shock protein 21, chloroplastic [KO:K13993]
103859533  15.4 kDa class V heat shock protein [KO:K13993]
103862989  23.6 kDa heat shock protein, mitochondrial [KO:K13993]
103833095  23.5 kDa heat shock protein, mitochondrial-like [KO:K13993]
103851393  inactive protein RESTRICTED TEV MOVEMENT 2 [KO:K13993]
103845392  18.1 kDa class I heat shock protein [KO:K13993]
103850811  17.6 kDa class II heat shock protein [KO:K13993]
103840065  22.0 kDa heat shock protein-like [KO:K13993]
103834227  15.4 kDa class V heat shock protein [KO:K13993]
103843285  17.6 kDa class I heat shock protein 2-like [KO:K13993]
103832638  17.4 kDa class III heat shock protein-like [KO:K13993]
103871208  26.5 kDa heat shock protein, mitochondrial [KO:K13993]
103873314  17.4 kDa class I heat shock protein [KO:K13993]
103857187  23.5 kDa heat shock protein, mitochondrial [KO:K13993]
103858554  22.0 kDa heat shock protein [KO:K13993]
103856611  18.1 kDa class I heat shock protein [KO:K13993]
103851557  18.1 kDa class I heat shock protein [KO:K13993]
103856475  inactive protein RESTRICTED TEV MOVEMENT 2 [KO:K13993]
103863742  15.7 kDa heat shock protein, peroxisomal [KO:K13993]
103860601  17.4 kDa class III heat shock protein [KO:K13993]
103827635  14.7 kDa heat shock protein [KO:K13993]
103871327  OVARIAN TUMOR DOMAIN-containing deubiquitinating enzyme 2 isoform X1 [KO:K13719] [EC:3.1.2.-]
103869516  phospholipase A-2-activating protein [KO:K14018]
103859777  phospholipase A-2-activating protein [KO:K14018]
103847526  ubiquitin receptor RAD23d [KO:K10839]
103846358  ubiquitin receptor RAD23c-like [KO:K10839]
108870184  ubiquitin receptor RAD23c-like isoform X1 [KO:K10839]
103846357  ubiquitin receptor RAD23c [KO:K10839]
103830472  ubiquitin receptor RAD23b [KO:K10839]
103842858  probable ubiquitin receptor RAD23a [KO:K10839]
103872412  probable ubiquitin receptor RAD23a [KO:K10839]
103858967  ubiquitin receptor RAD23c [KO:K10839]
103850114  ubiquitin receptor RAD23d [KO:K10839]
103863786  ubiquitin receptor RAD23d [KO:K10839]
103837794  ubiquitin domain-containing protein DSK2b isoform X1 [KO:K04523]
103874189  ubiquitin domain-containing protein DSK2b [KO:K04523]
103845986  ubiquitin domain-containing protein DSK2b [KO:K04523]
103874613  peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase [KO:K01456] [EC:3.5.1.52]
103841330  ataxin-3 homolog [KO:K11863] [EC:3.4.22.-]
103863262  ataxin-3 homolog [KO:K11863] [EC:3.4.22.-]
103846414  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
103850982  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
103866961  eukaryotic translation initiation factor 2 subunit alpha homolog [KO:K03237]
103857925  eukaryotic translation initiation factor 2 subunit alpha homolog [KO:K03237]
103865783  eukaryotic translation initiation factor 2 subunit alpha homolog [KO:K03237]
108870147  eukaryotic translation initiation factor 2 subunit alpha homolog [KO:K03237]
103856389  subtilisin-like protease SBT6.1 isoform X1 [KO:K08653] [EC:3.4.21.112]
103858089  membrane-bound transcription factor site-2 protease homolog isoform X1 [KO:K07765] [EC:3.4.24.85]
103874122  serine/threonine-protein kinase/endoribonuclease IRE1a [KO:K08852] [EC:2.7.11.1 3.1.26.-]
103842338  probable E3 ubiquitin ligase SUD1 isoform X1 [KO:K10661] [EC:2.3.2.27]
103850604  probable E3 ubiquitin ligase SUD1 isoform X1 [KO:K10661] [EC:2.3.2.27]
103850648  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
103870726  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
103859173  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
103870349  probable E3 ubiquitin ligase SUD1 isoform X2 [KO:K10661] [EC:2.3.2.27]
103834540  probable E3 ubiquitin ligase SUD1 [KO:K10661] [EC:2.3.2.27]
103839514  ubiquitin-conjugating enzyme E2 32 [KO:K10578] [EC:2.3.2.23]
103869994  ubiquitin-conjugating enzyme E2 32 [KO:K10578] [EC:2.3.2.23]
103842801  ubiquitin-conjugating enzyme E2 34 isoform X1 [KO:K04554] [EC:2.3.2.23]
103872515  ubiquitin-conjugating enzyme E2 34 [KO:K04554] [EC:2.3.2.23]
103835962  ubiquitin-conjugating enzyme E2 34 [KO:K04554] [EC:2.3.2.23]
103845355  ubiquitin-conjugating enzyme E2 7 [KO:K10575] [EC:2.3.2.23]
103851586  ubiquitin-conjugating enzyme E2 7 [KO:K10575] [EC:2.3.2.23]
103841444  ubiquitin-conjugating enzyme E2 14 [KO:K10575] [EC:2.3.2.23]
103830011  ubiquitin-conjugating enzyme E2 14 [KO:K10575] [EC:2.3.2.23]
103863169  ubiquitin-conjugating enzyme E2 14 [KO:K10575] [EC:2.3.2.23]
103840247  ERAD-associated E3 ubiquitin-protein ligase HRD1A [KO:K10601] [EC:2.3.2.27]
103852213  ERAD-associated E3 ubiquitin-protein ligase HRD1B isoform X1 [KO:K10601] [EC:2.3.2.27]
103846598  E3 ubiquitin-protein ligase RMA1 [KO:K10666] [EC:2.3.2.27]
103861695  E3 ubiquitin-protein ligase RMA3 [KO:K10666] [EC:2.3.2.27]
103830134  uncharacterized protein LOC103830134 [KO:K10666] [EC:2.3.2.27]
103861821  E3 ubiquitin-protein ligase RMA2 [KO:K10666] [EC:2.3.2.27]
103867947  E3 ubiquitin-protein ligase RMA2 isoform X2 [KO:K10666] [EC:2.3.2.27]
103841700  uncharacterized protein LOC103841700 [KO:K10666] [EC:2.3.2.27]
103867189  E3 ubiquitin-protein ligase RMA3 isoform X1 [KO:K10666] [EC:2.3.2.27]
103249148  E3 ubiquitin-protein ligase RNF185 [KO:K10666] [EC:2.3.2.27]
103872727  E3 ubiquitin-protein ligase RNF185 [KO:K10666] [EC:2.3.2.27]
103853398  ERAD-associated E3 ubiquitin-protein ligase component HRD3A [KO:K14026]
103872588  ERAD-associated E3 ubiquitin-protein ligase component HRD3A [KO:K14026]
103863030  E3 ubiquitin protein ligase RIN2 isoform X2 [KO:K10636] [EC:2.3.2.36]
103834881  E3 ubiquitin protein ligase RIN2 isoform X1 [KO:K10636] [EC:2.3.2.36]
103861538  E3 ubiquitin protein ligase RIN2 [KO:K10636] [EC:2.3.2.36]
103870675  E3 ubiquitin-protein ligase CHIP [KO:K09561] [EC:2.3.2.27]
103859333  ubiquitin-conjugating enzyme E2 11 [KO:K06689] [EC:2.3.2.23]
103851847  ubiquitin-conjugating enzyme E2 30 isoform X1 [KO:K06689] [EC:2.3.2.23]
103838220  ubiquitin-conjugating enzyme E2 28 [KO:K06689] [EC:2.3.2.23]
103844808  ubiquitin-conjugating enzyme E2 10 [KO:K06689] [EC:2.3.2.23]
103848719  ubiquitin-conjugating enzyme E2 11 [KO:K06689] [EC:2.3.2.23]
103870601  ubiquitin-conjugating enzyme E2 11 [KO:K06689] [EC:2.3.2.23]
103868687  probable ubiquitin-conjugating enzyme E2 31 isoform X1 [KO:K06689] [EC:2.3.2.23]
103838144  ubiquitin-conjugating enzyme E2 28 isoform X1 [KO:K06689] [EC:2.3.2.23]
103845050  ubiquitin-conjugating enzyme E2 30 isoform X2 [KO:K06689] [EC:2.3.2.23]
103846025  ubiquitin-conjugating enzyme E2 29 [KO:K06689] [EC:2.3.2.23]
103856951  ubiquitin-conjugating enzyme E2 30 [KO:K06689] [EC:2.3.2.23]
103860482  ubiquitin-conjugating enzyme E2 29 [KO:K06689] [EC:2.3.2.23]
103868813  probable ubiquitin-conjugating enzyme E2 31 [KO:K06689] [EC:2.3.2.23]
103852040  ubiquitin-conjugating enzyme E2 10 [KO:K06689] [EC:2.3.2.23]
103845664  RING-box protein 1a [KO:K03868] [EC:2.3.2.32]
103851357  RING-box protein 1a [KO:K03868] [EC:2.3.2.32]
103856451  RING-box protein 1a [KO:K03868] [EC:2.3.2.32]
103836734  cullin-1 [KO:K03347]
103858756  cullin-1 [KO:K03347]
103848439  SKP1-like protein 14 [KO:K03094]
103829444  SKP1-like protein 3 isoform X3 [KO:K03094]
103829446  SKP1-like protein 4 [KO:K03094]
103830630  SKP1-like protein 1A [KO:K03094]
103832976  SKP1-like protein 13 [KO:K03094]
103830241  SKP1-like protein 1A [KO:K03094]
103832041  SKP1-like protein 1A isoform X1 [KO:K03094]
103841836  SKP1-like protein 13 [KO:K03094]
103841855  SKP1-like protein 1A [KO:K03094]
103841856  SKP1-like protein 13 [KO:K03094]
103841857  SKP1-like protein 13 [KO:K03094]
103871441  SKP1-like protein 13 [KO:K03094]
103871442  SKP1-like protein 1A [KO:K03094]
103872814  SKP1-like protein 4 [KO:K03094]
103862920  SKP1-like protein 1A [KO:K03094]
103852996  SKP1-like protein 1A [KO:K03094]
117128334  SKP1-like protein 18 [KO:K03094]
117128573  SKP1-like protein 5 [KO:K03094]
Compound
C00076  Calcium cation
G00009   
G00010   
G00011   
G00012   
G10694   
Reference
PMID:19491040
  Authors
Naidoo N
  Title
ER and aging-Protein folding and the ER stress response.
  Journal
Ageing Res Rev 8:150-9 (2009)
DOI:10.1016/j.arr.2009.03.001
Reference
PMID:18023214
  Authors
Malhotra JD, Kaufman RJ
  Title
The endoplasmic reticulum and the unfolded protein response.
  Journal
Semin Cell Dev Biol 18:716-31 (2007)
DOI:10.1016/j.semcdb.2007.09.003
Reference
PMID:20347046
  Authors
Maattanen P, Gehring K, Bergeron JJ, Thomas DY
  Title
Protein quality control in the ER: the recognition of misfolded proteins.
  Journal
Semin Cell Dev Biol 21:500-11 (2010)
DOI:10.1016/j.semcdb.2010.03.006
Reference
PMID:20219571
  Authors
Stolz A, Wolf DH
  Title
Endoplasmic reticulum associated protein degradation: a chaperone assisted journey to hell.
  Journal
Biochim Biophys Acta 1803:694-705 (2010)
DOI:10.1016/j.bbamcr.2010.02.005
Reference
PMID:20112977
  Authors
Dejgaard K, Theberge JF, Heath-Engel H, Chevet E, Tremblay ML, Thomas DY
  Title
Organization of the Sec61 translocon, studied by high resolution native electrophoresis.
  Journal
J Proteome Res 9:1763-71 (2010)
DOI:10.1021/pr900900x
Related
pathway
brp00510  N-Glycan biosynthesis
brp03050  Proteasome
brp03060  Protein export
KO pathway
ko04141   
LinkDB

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