KEGG   PATHWAY: bug00350
Entry
bug00350                    Pathway                                
Name
Tyrosine metabolism - Burkholderia sp. CCGE1001
Class
Metabolism; Amino acid metabolism
Pathway map
bug00350  Tyrosine metabolism
bug00350

Module
bug_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:bug00350]
bug_M00533  Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:bug00350]
Other DBs
GO: 0006570
Organism
Burkholderia sp. CCGE1001 [GN:bug]
Gene
BC1001_2635  histidinol-phosphate aminotransferase [KO:K00817] [EC:2.6.1.9]
BC1001_0297  histidinol-phosphate aminotransferase [KO:K00817] [EC:2.6.1.9]
BC1001_3198  histidinol-phosphate aminotransferase [KO:K00817] [EC:2.6.1.9]
BC1001_1137  aminotransferase class I and II [KO:K00832] [EC:2.6.1.57]
BC1001_3702  Aspartate transaminase [KO:K00832] [EC:2.6.1.57]
BC1001_5052  4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
BC1001_3308  4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
BC1001_5700  4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
BC1001_0489  homogentisate 1,2-dioxygenase [KO:K00451] [EC:1.13.11.5]
BC1001_0581  maleylacetoacetate isomerase [KO:K01800] [EC:5.2.1.2]
BC1001_0292  maleylacetoacetate isomerase [KO:K01800] [EC:5.2.1.2]
BC1001_0490  fumarylacetoacetase [KO:K01555] [EC:3.7.1.2]
BC1001_0210  fumarylacetoacetate (FAA) hydrolase [KO:K16171] [EC:3.7.1.2]
BC1001_0851  Aldehyde Dehydrogenase [KO:K00146] [EC:1.2.1.39]
BC1001_2901  S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
BC1001_PA6253  flhA; S-(hydroxymethyl)glutathione dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
BC1001_5006  Alcohol dehydrogenase GroES domain protein [KO:K13953] [EC:1.1.1.1]
BC1001_4057  zinc-binding alcohol dehydrogenase family protein [KO:K13953] [EC:1.1.1.1]
BC1001_0843  Alcohol dehydrogenase zinc-binding domain protein [KO:K00001] [EC:1.1.1.1]
BC1001_5333  3,4-dihydroxyphenylacetate 2,3-dioxygenase [KO:K00455] [EC:1.13.11.15]
BC1001_5334  5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase [KO:K00151] [EC:1.2.1.60]
BC1001_5332  5-carboxymethyl-2-hydroxymuconate isomerase [KO:K01826] [EC:5.3.3.10]
BC1001_5335  4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit [KO:K05921] [EC:4.1.1.68 5.3.3.-]
BC1001_5336  fumarylacetoacetate (FAA) hydrolase [KO:K05921] [EC:4.1.1.68 5.3.3.-]
BC1001_5331  2-oxo-hepta-3-ene-1,7-dioic acid hydratase [KO:K02509] [EC:4.2.1.-]
BC1001_5330  2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [KO:K02510] [EC:4.1.2.52]
BC1001_5131  succinic semialdehyde dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BC1001_4152  succinic semialdehyde dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BC1001_4828  succinic semialdehyde dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BC1001_1558  Aldehyde Dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BC1001_2014  Aldehyde Dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BC1001_0579  gentisate 1,2-dioxygenase [KO:K00450] [EC:1.13.11.4]
BC1001_0580  fumarylacetoacetate (FAA) hydrolase [KO:K16165] [EC:3.7.1.20]
BC1001_0291  fumarylacetoacetate (FAA) hydrolase [KO:K16165] [EC:3.7.1.20]
BC1001_3756  Malate/L-lactate dehydrogenase [KO:K13574] [EC:1.1.1.237 1.1.1.-]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
bug00020  Citrate cycle (TCA cycle)
bug00360  Phenylalanine metabolism
bug00400  Phenylalanine, tyrosine and tryptophan biosynthesis
bug00620  Pyruvate metabolism
bug00621  Dioxin degradation
bug00650  Butanoate metabolism
KO pathway
ko00350   
LinkDB

DBGET integrated database retrieval system