KEGG PATHWAY: bvg00999

KEGG

PATHWAY: bvg00999

Entry

bvg00999                    Pathway

Name

Biosynthesis of various plant secondary metabolites - Beta vulgaris (sugar beet)

Including

Crocin biosynthesis, Ginsenoside biosynthesis, Saponin adjuvant biosynthesis, Cannabidiol biosynthesis, Mugineic acid biosynthesis, Pentagalloylglucose biosynthesis, Benzoxazinoid biosynthesis, Gramine biosynthesis, Coumarin biosynthesis, Furanocoumarin biosynthesis, Hordatine biosynthesis, Podophyllotoxin biosynthesis

Class

Metabolism; Biosynthesis of other secondary metabolites

Pathway map

Biosynthesis of various plant secondary metabolites

Organism

Beta vulgaris (sugar beet) [GN:bvg]

Gene

beta-amyrin synthase [KO:K15813] [EC:5.4.99.39]

beta-amyrin 28-oxidase [KO:K20667] [EC:1.14.14.126]

beta-amyrin 28-oxidase [KO:K20667] [EC:1.14.14.126]

S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]

S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]

nicotianamine synthase [KO:K05953] [EC:2.5.1.43]

non-functional NADPH-dependent codeinone reductase 2 [KO:K22374] [EC:1.1.1.285]

non-functional NADPH-dependent codeinone reductase 2 [KO:K22374] [EC:1.1.1.285]

bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic [KO:K13832] [EC:4.2.1.10 1.1.1.25]

bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic [KO:K13832] [EC:4.2.1.10 1.1.1.25]

beta-glucosidase 24-like [KO:K01188] [EC:3.2.1.21]

beta-glucosidase BoGH3B [KO:K05349] [EC:3.2.1.21]

beta-glucosidase BoGH3B [KO:K05349] [EC:3.2.1.21]

beta-glucosidase BoGH3B [KO:K05349] [EC:3.2.1.21]

beta-glucosidase BoGH3B [KO:K05349] [EC:3.2.1.21]

beta-glucosidase BoGH3B-like [KO:K05349] [EC:3.2.1.21]

beta-glucosidase BoGH3B [KO:K05349] [EC:3.2.1.21]

beta-glucosidase BoGH3B-like [KO:K05349] [EC:3.2.1.21]

beta-glucosidase 46-like [KO:K05350] [EC:3.2.1.21]

beta-glucosidase 18-like [KO:K05350] [EC:3.2.1.21]

beta-glucosidase 18-like [KO:K05350] [EC:3.2.1.21]

beta-glucosidase 44 [KO:K05350] [EC:3.2.1.21]

feruloyl CoA ortho-hydroxylase 1-like [KO:K06892] [EC:1.14.11.61]

scopoletin glucosyltransferase [KO:K23260] [EC:2.4.1.128]

scopoletin glucosyltransferase [KO:K23260] [EC:2.4.1.128]

scopoletin glucosyltransferase [KO:K23260] [EC:2.4.1.128]

scopoletin glucosyltransferase-like [KO:K23260] [EC:2.4.1.128]

isoflavone reductase homolog [KO:K21568] [EC:1.23.1.1 1.23.1.2 1.23.1.3 1.23.1.4]

Compound

S-Adenosyl-L-methionine

Acetyl-CoA

Oxaloacetate

L-Aspartate

L-Methionine

Phosphoenolpyruvate

L-Tryptophan

L-Phenylalanine

L-Tyrosine

Malonyl-CoA

Anthranilate

Agmatine

p-Coumaroyl-CoA

Chorismate

Prephenate

Caffeoyl-CoA

Geranylgeranyl diphosphate

Feruloyl-CoA

trans-Cinnamate

trans,trans-Farnesyl diphosphate

Indole

Shikimate

Coniferyl alcohol

Squalene

Bergaptol

Xanthotoxol

(S)-2,3-Epoxysqualene

1-O-Galloyl-beta-D-glucose

3-(2-Hydroxyphenyl)propanoate

Gallate

Scopolin

Bergapten

Scopoletin

trans-2-Hydroxycinnamate

Xanthotoxin

Isopimpinellin

Dihydrocoumarin

3-Dehydroshikimate

5-Hydroxyxanthotoxin

Indoleglycerol phosphate

p-Coumaroylagmatine

Pentagalloylglucose

DIMBOA-glucoside

trans-beta-D-Glucosyl-2-hydroxycinnamate

Nicotianamine

(+)-Pinoresinol

cis-2-Hydroxycinnamate

cis-beta-D-Glucosyl-2-hydroxycinnamate

Coumarin

Zeaxanthin

Dronabinol

Cannabidiol

Gramine

Hordatine A

Hordatine B

Crocetin

Crocin

beta-Amyrin

Echinocystic acid

Ginsenoside Rg1

Quillaic acid

Angelicin

Esculetin

Fraxetin

Marmesin

Psoralen

Scoparone

Umbelliferone

Deoxypodophyllotoxin

Dihydroanhydropodorhizol

Lariciresinol

Matairesinol

Cannabidiolic acid

Podophyllotoxin

3-Hydroxyindolin-2-one

Indolin-2-one

2'-Deoxymugineic acid

3''-Deamino-3''-oxonicotianamine

Mugineic acid

3-Epihydroxymugineic acid

3-Epihydroxy-2'-deoxymugineic acid

HBOA

DIBOA

DIBOA-glucoside

Picrocrocin

Safranal

Oleanolic acid

trans-Crocetin (beta-D-glucosyl) (beta-D-gentibiosyl) ester

TRIBOA-glucoside

Isoscopoletin

Osthenol

Demethylsuberosin

Secoisolariciresinol

Feruloylagmatine

(+)-Columbianetin

Crocetin dialdehyde

(3S)-3-Hydroxycyclocitral

Dammarenediol-II

beta-D-Glucosyl crocetin

Bis(beta-D-glucosyl) crocetin

beta-D-Gentiobiosyl crocetin

Cannabigerolate

3,5,7-Trioxododecanoyl-CoA

2,4-Dihydroxy-6-pentylbenzoate

(-)-Lariciresinol

(-)-Pinoresinol

(+)-Secoisolariciresinol

Ginsenoside Rb1

Protopanaxadiol

Protopanaxatriol

Ginsenoside Rd

Ginsenoside Rg3

Ginsenoside F2

Ginsenoside F1

beta-Citraurin

Bursehernin

(-)-5'-Demethylyatein

Pluviatolide

6-Hydroxyferuloyl-CoA

3-(Aminomethyl)indole

(1H-Indol-3-yl)-N-methylmethanamine

Delta9-Tetrahydrocannabinolate

Sideretin

2,4-Dihydroxycinnamoyl-CoA

Ginsenoside C-K

(20S)-Ginsenoside Rh2

Ginsenoside Rh1

Bergamottin

Epoxybergamottin

6',7'-Dihydroxybergamottin

3,5-Dehydroshikimate

5,8-Dihydroxypsoralen

8-Hydroxybergapten

6,7,8-Trihydroxycoumarin

Quillaic acid 3-O-beta-D-glucuronide

Quillaic acid 3-O-beta-D-galactosyl-1,2-beta-D-glucuronide

Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide

Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide

Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside

Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-fucoside

Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside

Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-alpha-L-rhamnosyl-1,2-beta-D-fucoside

Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside

Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside

Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside

Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-xylosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside

Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside

Quillaic acid 3-O-alpha-L-rhamnosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide-28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-alpha-L-rhamnosyl-1,2-beta-D-fucoside

Quillaic acid 3-O-beta-D-xylosyl-1,3-(beta-D-galactosyl-1,2)-beta-D-glucuronide 28-O-beta-D-apiosyl-1,3-beta-D-xylosyl-1,4-(beta-D-glucosyl-1,3)-alpha-L-rhamnosyl-1,2-(alpha-L-rhamnosyl-1,3)-4-O-acetyl-beta-D-fucoside

Reference

Authors

Nagatoshi M, Terasaka K, Owaki M, Sota M, Inukai T, Nagatsu A, Mizukami H

Title

UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides.

Journal

FEBS Lett 586:1055-61 (2012)
DOI:10.1016/j.febslet.2012.03.003

Reference

Authors

Taura F, Sirikantaramas S, Shoyama Y, Yoshikai K, Shoyama Y, Morimoto S

Title

Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa.

Journal

FEBS Lett 581:2929-34 (2007)
DOI:10.1016/j.febslet.2007.05.043

Reference

Authors

Higuchi K, Suzuki K, Nakanishi H, Yamaguchi H, Nishizawa NK, Mori S

Title

Cloning of nicotianamine synthase genes, novel genes involved in the biosynthesis of phytosiderophores.

Journal

Plant Physiol 119:471-80 (1999)
DOI:10.1104/pp.119.2.471

Reference

Authors

Ma JF, Shinada T, Matsuda C, Nomoto K

Title

Biosynthesis of phytosiderophores, mugineic acids, associated with methionine cycling.

Journal

J Biol Chem 270:16549-54 (1995)
DOI:10.1074/jbc.270.28.16549

Reference

Authors

Tahara K, Nishiguchi M, Funke E, Miyazawa SI, Miyama T, Milkowski C

Title

Dehydroquinate dehydratase/shikimate dehydrogenases involved in gallate biosynthesis of the aluminum-tolerant tree species Eucalyptus camaldulensis.

Journal

Planta 253:3 (2020)
DOI:10.1007/s00425-020-03516-w

Reference

Authors

Dugrand-Judek A, Olry A, Hehn A, Costantino G, Ollitrault P, Froelicher Y, Bourgaud F.

Title

The Distribution of Coumarins and Furanocoumarins in Citrus Species Closely Matches Citrus Phylogeny and Reflects the Organization of Biosynthetic Pathways.

Journal

PLoS One 10:e0142757 (2015)
DOI:10.1371/journal.pone.0142757

Reference

Authors

Hehmann M, Lukacin R, Ekiert H, Matern U

Title

Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase.

Journal

Eur J Biochem 271:932-40 (2004)
DOI:10.1111/j.1432-1033.2004.03995.x

Reference

Authors

Lau W, Sattely ES

Title

Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone.

Journal

Science 349:1224-8 (2015)
DOI:10.1126/science.aac7202

Reference

Authors

Reed J, Orme A, El-Demerdash A, Owen C, Martin LBB, Misra RC, Kikuchi S, Rejzek M, Martin AC, Harkess A, Leebens-Mack J, Louveau T, Stephenson MJ, Osbourn A.

Title

Elucidation of the pathway for biosynthesis of saponin adjuvants from the soapbark tree.

Journal

Science 379:1252-1264 (2023)
DOI:10.1126/science.adf3727

Related
pathway

Glycolysis / Gluconeogenesis

Citrate cycle (TCA cycle)

Cysteine and methionine metabolism

Phenylalanine, tyrosine and tryptophan biosynthesis

Terpenoid backbone biosynthesis

Phenylpropanoid biosynthesis

KO pathway

LinkDB

DBGET integrated database retrieval system