KEGG   PATHWAY: cuca03083
Entry
cuca03083                   Pathway                                
Name
Polycomb repressive complex - Cuculus canorus (common cuckoo)
Class
Genetic Information Processing; Chromosome
Pathway map
cuca03083  Polycomb repressive complex
cuca03083

Organism
Cuculus canorus (common cuckoo) [GN:cuca]
Gene
104054392  EZH1; histone-lysine N-methyltransferase EZH1 [KO:K17451] [EC:2.1.1.356]
104065929  EZH2; histone-lysine N-methyltransferase EZH2 isoform X2 [KO:K11430] [EC:2.1.1.356]
104068405  EED; polycomb protein EED [KO:K11462]
104061990  SUZ12; polycomb protein SUZ12 [KO:K11463]
104060085  RBBP4; histone-binding protein RBBP4 isoform X1 [KO:K10752]
104063392  RBBP7; histone-binding protein RBBP7 [KO:K11659]
104055114  MTF2; metal-response element-binding transcription factor 2 [KO:K11485]
104066849  PHF19; PHD finger protein 19 isoform X1 [KO:K11486]
104055563  SKI/DACH domain-containing protein 1 [KO:K26259]
104059794  microtubule-associated protein futsch [KO:K26260]
104059750  ligand-dependent corepressor [KO:K26260]
104065615  AEBP2; zinc finger protein AEBP2 isoform X1 [KO:K17452]
104062126  JARID2; protein Jumonji isoform X1 [KO:K11478]
104066706  BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 [KO:K08588] [EC:3.4.19.12]
104059966  ASXL3; LOW QUALITY PROTEIN: putative Polycomb group protein ASXL3 [KO:K11471]
104060795  ASXL1; polycomb group protein ASXL1 isoform X1 [KO:K11471]
104061777  ASXL2; putative Polycomb group protein ASXL2 isoform X2 [KO:K11471]
104069007  OGT; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
104057792  YY1; transcriptional repressor protein YY1 [KO:K09201]
104058540  MBD5; methyl-CpG-binding domain protein 5 isoform X1 [KO:K23219]
104062545  FOXK1; forkhead box protein K1 isoform X1 [KO:K09404]
104057590  FOXK2; forkhead box protein K2 [KO:K09404]
104055257  RNF2; E3 ubiquitin-protein ligase RING2 [KO:K10695] [EC:2.3.2.27]
128849612  RING1; E3 ubiquitin-protein ligase RING1 [KO:K10695] [EC:2.3.2.27]
104055566  PCGF2; polycomb group RING finger protein 2 isoform X1 [KO:K11460]
104057686  BMI1; polycomb complex protein BMI-1 isoform X1 [KO:K11459]
104059439  CBX2; chromobox protein homolog 2 [KO:K11451]
104059460  CBX4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
104065923  CBX6; chromobox protein homolog 6 isoform X1 [KO:K11453]
104065895  CBX7; chromobox protein homolog 7 isoform X3 [KO:K11454]
104059440  CBX8; chromobox protein homolog 8 isoform X1 [KO:K11455]
104060627  PHC1; polyhomeotic-like protein 1 isoform X1 [KO:K11456]
104062259  PHC2; polyhomeotic-like protein 2 isoform X1 [KO:K11457]
104061843  PHC3; polyhomeotic-like protein 3 isoform X1 [KO:K11458]
104063390  SCML2; sex comb on midleg-like protein 2 isoform X1 [KO:K11465]
104063555  SCMH1; polycomb protein SCMH1 isoform X1 [KO:K11461]
104066387  SFMBT2; scm-like with four MBT domains protein 2 isoform X1 [KO:K26269]
104066693  SFMBT1; scm-like with four MBT domains protein 1 [KO:K26269]
128849974  aurora kinase C-like [KO:K11479] [EC:2.7.11.1]
104066517  UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 [KO:K06689] [EC:2.3.2.23]
104054830  UBE2D2; ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
104068731  UBE2D3; ubiquitin-conjugating enzyme E2 D3 [KO:K06689] [EC:2.3.2.23]
104064774  USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 [KO:K11844] [EC:3.4.19.12]
104062431  USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1 [KO:K11844] [EC:3.4.19.12]
104061217  RYBP; RING1 and YY1-binding protein [KO:K11469]
104062400  YAF2; YY1-associated factor 2 [KO:K11468]
104057997  PCGF1; polycomb group RING finger protein 1 isoform X1 [KO:K11487]
104063332  KDM2A; lysine-specific demethylase 2A isoform X1 [KO:K10276] [EC:1.14.11.27]
104058827  KDM2B; lysine-specific demethylase 2B isoform X9 [KO:K10276] [EC:1.14.11.27]
104057284  BCOR; BCL-6 corepressor isoform X1 [KO:K23215]
104060510  BCORL1; BCL-6 corepressor-like protein 1 [KO:K26199]
104060678  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
104056325  USP7; ubiquitin carboxyl-terminal hydrolase 7 [KO:K11838] [EC:3.4.19.12]
104062610  PCGF3; polycomb group RING finger protein 3 isoform X1 [KO:K11488]
104067869  PCGF5; polycomb group RING finger protein 5 isoform X1 [KO:K11489]
128849600  CSNK2B; casein kinase II subunit beta [KO:K03115]
104064678  AUTS2; autism susceptibility gene 2 protein isoform X1 [KO:K23214]
104054666  FBRSL1; fibrosin-1-like protein isoform X1 [KO:K26254]
104054377  DCAF7; DDB1- and CUL4-associated factor 7 [KO:K11805]
104062176  TEX10; testis-expressed protein 10 [KO:K14827]
104068132  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
104055501  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
104054730  PCGF6; polycomb group RING finger protein 6 isoform X1 [KO:K11470]
104058194  E2F6; transcription factor E2F6 isoform X1 [KO:K09390]
104056621  TFDP1; transcription factor Dp-1 isoform X1 [KO:K04683]
104064422  MAX; protein max isoform X1 [KO:K04453]
104067315  MGA; MAX gene-associated protein isoform X1 [KO:K23399]
104063210  L3MBTL1; lethal(3)malignant brain tumor-like protein 1 isoform X1 [KO:K24387]
104059525  lethal(3)malignant brain tumor-like protein 4 isoform X1 [KO:K24387]
104055500  L3MBTL2; lethal(3)malignant brain tumor-like protein 2 isoform X1 [KO:K24387]
104061015  L3MBTL3; lethal(3)malignant brain tumor-like protein 3 isoform X1 [KO:K24387]
104059038  CBX3; chromobox protein homolog 3 isoform X2 [KO:K11586]
104060093  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
104068995  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
LinkDB

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