KEGG   PATHWAY: dwi03083
Entry
dwi03083                    Pathway                                
Name
Polycomb repressive complex - Drosophila willistoni
Class
Genetic Information Processing; Chromosome
Pathway map
dwi03083  Polycomb repressive complex
dwi03083

Organism
Drosophila willistoni [GN:dwi]
Gene
6646360  histone-lysine N-methyltransferase E(z) isoform X1 [KO:K11430] [EC:2.1.1.356]
6642210  polycomb protein esc [KO:K11462]
6642349  polycomb protein esc [KO:K11462]
6639025  polycomb protein Su(z)12 isoform X1 [KO:K11463]
6651741  chromatin assembly factor 1 p55 subunit [KO:K10752]
6648738  polycomb protein Pcl [KO:K11485]
6639815  polycomb protein Pcl [KO:K11485]
6639727  zinc finger protein jing isoform X1 [KO:K17452]
6645839  mucin-5AC [KO:K11478]
6643431  ubiquitin carboxyl-terminal hydrolase calypso [KO:K08588] [EC:3.4.19.12]
6640825  polycomb protein Asx [KO:K11471]
6640415  UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit [KO:K09667] [EC:2.4.1.255]
6651638  host cell factor isoform X1 [KO:K14966]
6651325  polycomb protein PHO [KO:K09201]
6645805  polycomb protein PHO [KO:K09201]
6649695  AF4/FMR2 family member lilli isoform X3 [KO:K23219]
6645807  forkhead box protein K2 [KO:K09404]
6647165  E3 ubiquitin-protein ligase RING1 [KO:K10695] [EC:2.3.2.27]
6638152  polycomb group protein Psc [KO:K11459]
6645743  polycomb group protein Pc [KO:K11455]
6648672  polyhomeotic-proximal chromatin protein isoform X1 [KO:K11456]
6647405  polycomb protein Scm [KO:K11461]
6642612  polycomb protein Sfmbt isoform X1 [KO:K26269]
6651774  aurora kinase B [KO:K11479] [EC:2.7.11.1]
6647220  ubiquitin-conjugating enzyme E2-17 kDa [KO:K06689] [EC:2.3.2.23]
6644644  ubiquitin-conjugating enzyme E2 4 [KO:K06689] [EC:2.3.2.23]
6641370  ubiquitin carboxyl-terminal hydrolase 45 [KO:K11844] [EC:3.4.19.12]
6640479  YY1-associated factor 2 [KO:K11468]
6647996  jmjC domain-containing histone demethylation protein 1 [KO:K10276] [EC:1.14.11.27]
6640606  S-phase kinase-associated protein 1 [KO:K03094]
6649632  SKP1-like protein 15 [KO:K03094]
6643164  S-phase kinase-associated protein 1-like [KO:K03094]
6646207  S-phase kinase-associated protein 1-like [KO:K03094]
6648904  S-phase kinase-associated protein 1-like [KO:K03094]
6639099  S-phase kinase-associated protein 1 [KO:K03094]
6639196  S-phase kinase-associated protein 1 [KO:K03094]
6644813  S-phase kinase-associated protein 1 [KO:K03094]
6652545  S-phase kinase-associated protein 1 [KO:K03094]
6649007  ubiquitin carboxyl-terminal hydrolase 7 [KO:K11838] [EC:3.4.19.12]
6645719  polycomb group RING finger protein 3 [KO:K11488]
6639655  casein kinase II subunit beta' [KO:K03115]
6639758  suppressor-of-stellate-like protein isoform X1 [KO:K03115]
6652916  casein kinase II subunit beta isoform X1 [KO:K03115]
6644572  DDB1- and CUL4-associated factor 7 [KO:K11805]
6652918  testis-expressed protein 10 [KO:K14827]
6649171  histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
6640425  transcription factor Dp isoform X1 [KO:K04683]
6643095  protein max [KO:K04453]
6649848  uncharacterized protein LOC6649848 [KO:K24387]
6646870  chromobox protein homolog 3 [KO:K11586]
6640136  WD repeat-containing protein 5 [KO:K14963]
6641120  protein will die slowly [KO:K14963]
6638627  histone deacetylase HDAC1 [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
LinkDB

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