PATHWAY: eak02010 Help
Entry
Name
ABC transporters - Sinorhizobium alkalisoli
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Sinorhizobium alkalisoli [GN:
eak ]
Gene
EKH55_4977 Hydroxymethylpyrimidine ABC transporter, substrate-binding component [KO:K15553 ]
EKH55_4975 Hydroxymethylpyrimidine ABC transporter, transmembrane component [KO:K15554 ]
EKH55_2879 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA [KO:K02020 ]
EKH55_2230 ABC transporter, periplasmic spermidine putrescine-binding protein PotD [KO:K11069 ]
EKH55_4029 ABC transporter, periplasmic spermidine putrescine-binding protein PotD [KO:K11069 ]
EKH55_2232 Spermidine Putrescine ABC transporter permease component potC [KO:K11070 ]
EKH55_2231 Spermidine Putrescine ABC transporter permease component PotB [KO:K11071 ]
EKH55_0303 Putrescine ABC transporter putrescine-binding protein PotF [KO:K11073 ]
EKH55_4710 Spermidine Putrescine ABC transporter permease component PotB [KO:K11079 ]
EKH55_1343 L-proline glycine betaine binding ABC transporter protein ProX [KO:K02002 ]
EKH55_0145 L-proline glycine betaine binding ABC transporter protein ProX [KO:K02002 ]
EKH55_2395 L-proline glycine betaine binding ABC transporter protein ProX [KO:K02002 ]
EKH55_1639 L-proline glycine betaine binding ABC transporter protein ProX [KO:K02002 ]
EKH55_1884 L-proline glycine betaine binding ABC transporter protein ProX [KO:K02002 ]
EKH55_0670 L-proline glycine betaine binding ABC transporter protein ProX [KO:K02002 ]
EKH55_1638 L-proline glycine betaine ABC transport system permease protein ProW [KO:K02001 ]
EKH55_2396 L-proline glycine betaine ABC transport system permease protein ProW [KO:K02001 ]
EKH55_2653 L-proline glycine betaine ABC transport system permease protein ProW [KO:K02001 ]
EKH55_0671 L-proline glycine betaine ABC transport system permease protein ProW [KO:K02001 ]
EKH55_5278 L-proline glycine betaine ABC transport system permease protein ProW [KO:K05846 ]
EKH55_5280 L-proline glycine betaine ABC transport system permease protein ProW [KO:K05846 ]
EKH55_5779 Various polyols ABC transporter, ATP-binding component [KO:K10111 ] [EC:7.5.2.-]
EKH55_2493 Various polyols ABC transporter, ATP-binding component [KO:K10111 ] [EC:7.5.2.-]
EKH55_3386 N-Acetyl-D-glucosamine ABC transport system ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
EKH55_4257 Various polyols ABC transporter, ATP-binding component [KO:K10111 ] [EC:7.5.2.-]
EKH55_4384 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
EKH55_5273 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
EKH55_4576 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K10111 ] [EC:7.5.2.-]
EKH55_4278 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K10111 ] [EC:7.5.2.-]
EKH55_3228 Putrescine transport ATP-binding protein PotG [KO:K10112 ] [EC:7.5.2.-]
EKH55_0730 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10112 ] [EC:7.5.2.-]
EKH55_5796 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
EKH55_0830 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10112 ] [EC:7.5.2.-]
EKH55_2560 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10112 ] [EC:7.5.2.-]
EKH55_5167 Dihydroxyacetone ABC transport system, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
EKH55_5168 Dihydroxyacetone ABC transport system, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
EKH55_1815 Nucleoside ABC transporter, permease protein 1 [KO:K10112 ] [EC:7.5.2.-]
EKH55_4420 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10112 ] [EC:7.5.2.-]
EKH55_3647 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10112 ] [EC:7.5.2.-]
EKH55_3694 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
EKH55_1188 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
EKH55_5454 Maltose/maltodextrin transport ATP-binding protein MalK [KO:K10112 ] [EC:7.5.2.-]
EKH55_3390 N-Acetyl-D-glucosamine ABC transport system, sugar-binding protein [KO:K10117 ]
EKH55_3389 N-Acetyl-D-glucosamine ABC transport system, permease protein 1 [KO:K10118 ]
EKH55_3388 N-Acetyl-D-glucosamine ABC transport system, permease protein 2 [KO:K10119 ]
EKH55_4268 Glycerol-3-phosphate ABC transporter, permease protein UgpE [KO:K10190 ]
EKH55_2496 Various polyols ABC transporter, periplasmic substrate-binding protein [KO:K10227 ]
EKH55_0280 Alpha-glucosides-binding periplasmic protein AglE precursor [KO:K10232 ]
EKH55_0281 ABC alpha-glucoside transporter, inner membrane subunit AglF [KO:K10233 ]
EKH55_4380 Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE [KO:K10236 ]
EKH55_4381 Maltose/maltodextrin ABC transporter, permease protein MalF [KO:K10237 ]
EKH55_4382 Maltose/maltodextrin ABC transporter, permease protein MalG [KO:K10238 ]
EKH55_1671 ABC-type transport system involved in resistance to organic solvent, periplasmic component [KO:K02067 ]
EKH55_1673 ABC-type transport system involved in resistance to organic solvent, permease component [KO:K02066 ]
EKH55_4682 Nucleoside ABC transporter, periplasmic nucleoside-binding protein [KO:K07335 ]
EKH55_4686 Nucleoside ABC transporter, periplasmic nucleoside-binding protein [KO:K07335 ]
EKH55_1368 Nucleoside ABC transporter, periplasmic nucleoside-binding protein [KO:K07335 ]
EKH55_4684 monosaccharide ABC transport system, permease component Ia [KO:K23535 ]
EKH55_1367 Putative deoxyribose-specific ABC transporter, permease protein [KO:K23536 ]
EKH55_3231 Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein [KO:K17315 ]
EKH55_3861 Ribose ABC transporter, periplasmic ribose-binding protein RbsB [KO:K10439 ]
EKH55_3884 Ribose ABC transport system, periplasmic ribose-binding protein RbsB [KO:K10439 ]
EKH55_3985 Ribose ABC transporter, periplasmic ribose-binding protein RbsB [KO:K10439 ]
EKH55_3288 periplasmic ribose-binding protein, sugar ABC transporter [KO:K10439 ]
EKH55_5042 Ribose ABC transporter, periplasmic ribose-binding protein [KO:K10439 ]
EKH55_5195 Ribose ABC transport system, periplasmic ribose-binding protein RbsB [KO:K10439 ]
EKH55_1893 putative fucose ABC transporter, substrate-binding component [KO:K10439 ]
EKH55_2949 Ribose ABC transporter, periplasmic ribose-binding protein RbsB [KO:K10439 ]
EKH55_3783 binding protein component precursor of ABC ribose transporter [KO:K10439 ]
EKH55_1930 Ribose ABC transport system, periplasmic ribose-binding protein RbsB [KO:K10439 ]
EKH55_3987 Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [KO:K10440 ]
EKH55_3988 Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [KO:K10440 ]
EKH55_5162 Putative sugar ABC transport system, periplasmic binding protein YtfQ precursor [KO:K23508 ]
EKH55_5159 Putative sugar ABC transport system, permease protein YjfF [KO:K23509 ]
EKH55_5160 Putative sugar ABC transport system, permease protein YtfT [KO:K23509 ]
EKH55_2452 Xylose ABC transporter, periplasmic xylose-binding protein XylF [KO:K10543 ]
EKH55_0098 Fructose ABC transporter, substrate-binding component FrcB [KO:K10552 ]
EKH55_0214 L-rhamnose ABC transporter, ATP-binding component [KO:K10562 ] [EC:7.5.2.-]
EKH55_4042 Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE [KO:K17237 ]
EKH55_2980 Glycerol-3-phosphate ABC transporter, permease protein UgpA [KO:K17321 ]
EKH55_2977 Glycerol-3-phosphate ABC transporter, permease protein UgpA [KO:K17322 ]
EKH55_2978 Glycerol-3-phosphate ABC transporter, permease protein UgpE [KO:K17323 ]
EKH55_2975 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K17324 ]
EKH55_2976 Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC [KO:K17325 ]
EKH55_4411 Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein [KO:K05813 ]
EKH55_3552 Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein [KO:K05813 ]
EKH55_4410 Glycerol-3-phosphate ABC transporter, permease protein UgpA [KO:K05814 ]
EKH55_3551 Glycerol-3-phosphate ABC transporter, permease protein UgpA [KO:K05814 ]
EKH55_4409 Glycerol-3-phosphate ABC transporter, permease protein UgpE [KO:K05815 ]
EKH55_3550 Glycerol-3-phosphate ABC transporter, permease protein UgpE [KO:K05815 ]
EKH55_0116 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS [KO:K02040 ]
EKH55_5250 Phosphonate ABC transporter phosphate-binding periplasmic component [KO:K02044 ]
EKH55_3457 Lysine-arginine-ornithine-binding periplasmic protein precursor [KO:K10018 ]
EKH55_1252 Glutamate Aspartate periplasmic binding protein precursor GltI [KO:K09969 ]
EKH55_1251 Glutamate Aspartate transport system permease protein GltJ [KO:K09970 ]
EKH55_1250 Glutamate Aspartate transport system permease protein GltK [KO:K09971 ]
EKH55_3205 L-Cystine ABC transporter, periplasmic cystine-binding protein [KO:K02424 ]
EKH55_4636 Dipeptide-binding ABC transporter, periplasmic substrate-binding component [KO:K01999 ]
EKH55_2271 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
EKH55_4856 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
EKH55_4072 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
EKH55_1555 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
EKH55_2531 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
EKH55_0541 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
EKH55_2936 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
EKH55_5806 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
EKH55_4639 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
EKH55_5695 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
EKH55_4857 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
EKH55_4070 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
EKH55_5807 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
EKH55_0801 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
EKH55_2537 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
EKH55_2939 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
EKH55_2536 Branched-chain amino acid transport system permease protein LivM [KO:K01998 ]
EKH55_2940 Branched-chain amino acid transport system permease protein LivM [KO:K01998 ]
EKH55_5694 Branched-chain amino acid transport system permease protein LivM [KO:K01998 ]
EKH55_5808 Branched-chain amino acid transport system permease protein LivM [KO:K01998 ]
EKH55_5809 Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 ]
EKH55_5697 Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 ]
EKH55_4859 Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 ]
EKH55_2535 Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 ]
EKH55_2937 Branched-chain amino acid transport ATP-binding protein LivG [KO:K01995 ]
EKH55_2534 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
EKH55_2938 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
EKH55_4638 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
EKH55_5696 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
EKH55_4860 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
EKH55_4071 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
EKH55_5810 Branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
EKH55_5236 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA [KO:K15580 ]
EKH55_0322 Dipeptide-binding ABC transporter, periplasmic substrate-binding component [KO:K12368 ]
EKH55_1836 Dipeptide-binding ABC transporter, periplasmic substrate-binding component [KO:K13889 ]
EKH55_1799 Zinc ABC transporter, inner membrane permease protein ZnuB [KO:K09816 ]
EKH55_2982 Manganese ABC transporter, periplasmic-binding protein SitA [KO:K11604 ]
EKH55_2984 Manganese ABC transporter, inner membrane permease protein SitC [KO:K11605 ]
EKH55_2985 Manganese ABC transporter, inner membrane permease protein SitD [KO:K11606 ]
EKH55_0502 Substrate-specific component BioY of biotin ECF transporter [KO:K03523 ]
EKH55_0503 Transmembrane component BioN of energizing module of biotin ECF transporter [KO:K16783 ]
EKH55_0504 ATPase component BioM of energizing module of biotin ECF transporter [KO:K16784 ] [EC:7.6.2.-]
EKH55_4792 Capsular polysaccharide export system inner membrane protein KpsE [KO:K10107 ]
EKH55_1045 Lipoprotein releasing system ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
EKH55_3165 Cytochrome c-type biogenesis protein CcmD, interacts with CcmCE [KO:K02196 ]
EKH55_3164 Cytochrome c-type biogenesis protein CcmC heme lyase for CcmE [KO:K02195 ]
EKH55_3163 ABC transporter involved in cytochrome c biogenesis, CcmB subunit [KO:K02194 ]
EKH55_2053 Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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