KEGG   PATHWAY: ecog00290
Entry
ecog00290                   Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Paremcibacter congregatus
Class
Metabolism; Amino acid metabolism
Pathway map
ecog00290  Valine, leucine and isoleucine biosynthesis
ecog00290

Module
ecog_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:ecog00290]
ecog_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:ecog00290]
ecog_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:ecog00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Paremcibacter congregatus [GN:ecog]
Gene
FIV45_09040  threonine ammonia-lyase [KO:K01754] [EC:4.3.1.19]
FIV45_12865  threonine/serine dehydratase [KO:K01754] [EC:4.3.1.19]
FIV45_00285  leuC; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
FIV45_00290  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
FIV45_00295  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
FIV45_01660  acetolactate synthase 3 large subunit [KO:K01652] [EC:2.2.1.6]
FIV45_16065  thiamine pyrophosphate-binding protein [KO:K01652] [EC:2.2.1.6]
FIV45_12500  thiamine pyrophosphate-binding protein [KO:K01652] [EC:2.2.1.6]
FIV45_17130  hypothetical protein [KO:K01652] [EC:2.2.1.6]
FIV45_13680  hypothetical protein [KO:K01652] [EC:2.2.1.6]
FIV45_15015  thiamine pyrophosphate-binding protein [KO:K01652] [EC:2.2.1.6]
FIV45_01665  ilvN; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
FIV45_01670  ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
FIV45_12905  ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
FIV45_02630  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
FIV45_07975  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
FIV45_17465  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
FIV45_10210  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
FIV45_08505  Glu/Leu/Phe/Val dehydrogenase [KO:K00263] [EC:1.4.1.9]
FIV45_04760  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
ecog00260  Glycine, serine and threonine metabolism
ecog00280  Valine, leucine and isoleucine degradation
ecog00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

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