KEGG   PATHWAY: ecok00310
Entry
ecok00310                   Pathway                                
Name
Lysine degradation - Escherichia coli K-12 MDS42
Class
Metabolism; Amino acid metabolism
Pathway map
ecok00310  Lysine degradation
ecok00310

Other DBs
GO: 0006554
Organism
Escherichia coli K-12 MDS42 [GN:ecok]
Gene
ECMDS42_0576  sucB; dihydrolipoyltranssuccinase [KO:K00658] [EC:2.3.1.61]
ECMDS42_0107  lpd; lipoamide dehydrogenase, E3 component is part of three enzyme complexes [KO:K00382] [EC:1.8.1.4]
ECMDS42_3284  fadB; fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [KO:K01825] [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
ECMDS42_1912  yfcX; fused enoyl-CoA hydratase and epimerase and isomerase/3-hydroxyacyl-CoA dehydrogenase, subunit of anaerobic fatty acid oxidation complex [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
ECMDS42_1792  atoB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
ECMDS42_2352  yqeF; predicted acyltransferase [KO:K00626] [EC:2.3.1.9]
ECMDS42_2348  ygeA; predicted racemase [KO:K25316] [EC:5.1.1.10]
ECMDS42_3571  cadA; lysine decarboxylase 1 [KO:K01582] [EC:4.1.1.18]
ECMDS42_0173  ldcC; lysine decarboxylase 2, constitutive [KO:K01582] [EC:4.1.1.18]
ECMDS42_2542  ygjG; putrescine:2-oxoglutaric acid aminotransferase, PLP-dependent [KO:K09251] [EC:2.6.1.82]
ECMDS42_1163  ydcW; medium chain aldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
ECMDS42_2166  gabT; 4-aminobutyrate aminotransferase, PLP-dependent [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
ECMDS42_2165  gabD; succinate-semialdehyde dehydrogenase I, NADP-dependent [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
ECMDS42_1140  ydcJ; conserved protein [KO:K25986] [EC:1.13.11.93]
ECMDS42_1359  ydiJ; predicted FAD-linked oxidoreductase [KO:K26063] [EC:1.1.-.-]
ECMDS42_1789  atoD; acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit [KO:K01034] [EC:2.8.3.8 2.8.3.9]
ECMDS42_1790  atoA; acetyl-CoA:acetoacetyl-CoA transferase, beta subunit [KO:K01035] [EC:2.8.3.8 2.8.3.9]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
ecok00020  Citrate cycle (TCA cycle)
ecok00300  Lysine biosynthesis
ecok00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

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