KEGG   PATHWAY: fve04626
Entry
fve04626                    Pathway                                
Name
Plant-pathogen interaction - Fragaria vesca (woodland strawberry)
Description
Plants lack animal-like adaptive immunity mechanisms, and therefore have evolved a specific system with multiple layers against invading pathogens. The primary response includes the perception of pathogens by cell-surface pattern-recognition receptors (PRRs) and is referred to as PAMP-triggered immunity (PTI). Activation of FLS2 and EFR triggers MAPK signaling pathway that activates defense genes for antimictobial compounds. The increase in the cytosolic Ca2+ concentration is also a regulator for production of reactive oxygen species and localized programmed cell death/hypersensitive response. The secondary response is called effector-triggered immunity (ETI). Pathogens can acquire the ability to suppress PTI by directly injecting effector proteins into the plant cell through secretion systems. In addition, pathogens can manipulate plant hormone signaling pathways to evade host immune responses using coronatine toxin. Some plants possess specific intracellular surveillance proteins (R proteins) to monitor the presence of pathogen virulence proteins. This ETI occurs with localized programmed cell death to arrest pathogen growth, resulting in cultivar-specific disease resistance.
Class
Organismal Systems; Environmental adaptation
Pathway map
fve04626  Plant-pathogen interaction
fve04626

Organism
Fragaria vesca (woodland strawberry) [GN:fve]
Gene
101304632  calcium-dependent protein kinase 26 [KO:K13412] [EC:2.7.11.1]
101309512  calcium-dependent protein kinase 34 [KO:K13412] [EC:2.7.11.1]
101312791  calcium-dependent protein kinase 11-like [KO:K13412] [EC:2.7.11.1]
101292190  calcium-dependent protein kinase 2-like [KO:K13412] [EC:2.7.11.1]
101293654  calcium-dependent protein kinase 8-like [KO:K13412] [EC:2.7.11.1]
101297901  calcium-dependent protein kinase 29 [KO:K13412] [EC:2.7.11.1]
101309915  calcium-dependent protein kinase 2-like [KO:K13412] [EC:2.7.11.1]
101297727  calcium-dependent protein kinase 3 [KO:K13412] [EC:2.7.11.1]
101306721  calcium-dependent protein kinase 10-like [KO:K13412] [EC:2.7.11.1]
101291863  calcium-dependent protein kinase 1-like [KO:K13412] [EC:2.7.11.1]
101307601  calcium-dependent protein kinase 13 [KO:K13412] [EC:2.7.11.1]
101299505  calcium-dependent protein kinase 32 [KO:K13412] [EC:2.7.11.1]
101310240  calcium-dependent protein kinase SK5-like [KO:K13412] [EC:2.7.11.1]
101294686  calcium-dependent protein kinase 20 [KO:K13412] [EC:2.7.11.1]
101299499  calcium-dependent protein kinase 26 [KO:K13412] [EC:2.7.11.1]
101298131  calcium and calcium/calmodulin-dependent serine/threonine-protein kinase-like [KO:K13412] [EC:2.7.11.1]
101306001  calcium-dependent protein kinase 24 [KO:K13412] [EC:2.7.11.1]
101301043  CDPK-related kinase 5 [KO:K13412] [EC:2.7.11.1]
101296729  CDPK-related kinase 5-like [KO:K13412] [EC:2.7.11.1]
101310558  CDPK-related kinase 3 [KO:K13412] [EC:2.7.11.1]
101304726  CDPK-related kinase 4-like [KO:K13412] [EC:2.7.11.1]
101299871  respiratory burst oxidase homolog protein A-like [KO:K13447] [EC:1.6.3.- 1.11.1.-]
101310280  respiratory burst oxidase homolog protein C [KO:K13447] [EC:1.6.3.- 1.11.1.-]
101313234  respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.6.3.- 1.11.1.-]
101294702  respiratory burst oxidase homolog protein E [KO:K13447] [EC:1.6.3.- 1.11.1.-]
101294470  respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.6.3.- 1.11.1.-]
101306915  respiratory burst oxidase homolog protein D [KO:K13447] [EC:1.6.3.- 1.11.1.-]
101293846  putative cyclic nucleotide-gated ion channel 15 [KO:K05391]
101311357  probable cyclic nucleotide-gated ion channel 14 [KO:K05391]
105350780  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101309615  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101311037  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
105352854  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101312949  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101291075  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101305221  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101312147  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101298656  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101315267  probable cyclic nucleotide-gated ion channel 5 [KO:K05391]
101293299  probable cyclic nucleotide-gated ion channel 20, chloroplastic [KO:K05391]
101298429  probable cyclic nucleotide-gated ion channel 16 [KO:K05391]
101299290  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101315327  probable cyclic nucleotide-gated ion channel 17 [KO:K05391]
105351257  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101309282  cyclic nucleotide-gated ion channel 2 [KO:K05391]
101293817  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101300753  probable cyclic nucleotide-gated ion channel 20, chloroplastic [KO:K05391]
101301626  cyclic nucleotide-gated ion channel 2-like [KO:K05391]
101313169  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
105353149  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101307632  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101314040  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101296790  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101292339  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101294228  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101296533  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101292640  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101296870  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101300161  putative cyclic nucleotide-gated ion channel 7 [KO:K05391]
101292046  putative cyclic nucleotide-gated ion channel 18 [KO:K05391]
101313465  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101308225  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101292429  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101294339  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
105350263  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101313535  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101304818  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101314615  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101300769  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
105353023  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101307542  cyclic nucleotide-gated ion channel 1-like [KO:K05391]
101315028  cyclic nucleotide-gated ion channel 4 [KO:K05391]
101306277  calmodulin-7 [KO:K02183]
101310634  calmodulin-7 [KO:K02183]
101297640  calmodulin-like [KO:K02183]
101303326  probable calcium-binding protein CML45 [KO:K02183]
101303402  putative calmodulin-like protein 2 [KO:K02183]
101308034  calmodulin-5/6/7/8-like [KO:K02183]
101308330  calmodulin-like [KO:K02183]
101309501  calmodulin-like protein 8 [KO:K02183]
101295526  probable calcium-binding protein CML29 [KO:K02183]
101313141  probable calcium-binding protein CML45 [KO:K02183]
101308877  probable calcium-binding protein CML47 [KO:K02183]
101296230  calmodulin-like protein 1 [KO:K13448]
101297834  probable calcium-binding protein CML15 [KO:K13448]
101292979  probable calcium-binding protein CML21 [KO:K13448]
101294531  probable calcium-binding protein CML18 [KO:K13448]
101299295  probable calcium-binding protein CML13 [KO:K13448]
101304964  probable calcium-binding protein CML25 [KO:K13448]
101311830  probable calcium-binding protein CML44 [KO:K13448]
101292606  probable calcium-binding protein CML41 [KO:K13448]
101295534  calcium-binding protein CML42-like [KO:K13448]
101309155  probable calcium-binding protein CML27 [KO:K13448]
101303028  calmodulin-like protein 11 [KO:K13448]
101295453  caltractin [KO:K13448]
101302652  probable calcium-binding protein CML22 [KO:K13448]
101306735  probable calcium-binding protein CML49 [KO:K13448]
101308636  probable calcium-binding protein CML48 [KO:K13448]
101310856  calmodulin-like protein 7 [KO:K13448]
101313108  probable calcium-binding protein CML16 [KO:K13448]
101313483  probable calcium-binding protein CML41 [KO:K13448]
101298441  probable calcium-binding protein CML36 [KO:K13448]
101299034  calcium-binding protein CML24-like [KO:K13448]
101307708  polcalcin Nic t 1 [KO:K13448]
101292012  putative calcium-binding protein CML19 [KO:K13448]
105350623  calmodulin-like protein 1 [KO:K13448]
105352384  calcium-binding protein CML38 [KO:K13448]
105353253  calcium-binding protein CML24 [KO:K13448]
105351659  putative calcium-binding protein CML19 [KO:K13448]
101294800  probable calcium-binding protein CML18 [KO:K13448]
101301911  NO-associated protein 1, chloroplastic/mitochondrial-like [KO:K13427] [EC:1.14.13.39]
101307253  NO-associated protein 1, chloroplastic/mitochondrial-like [KO:K13427] [EC:1.14.13.39]
101313449  mitogen-activated protein kinase homolog MMK2 [KO:K20600] [EC:2.7.11.24]
101309130  LRR receptor-like serine/threonine-protein kinase FLS2 [KO:K13420] [EC:2.7.11.1]
101303910  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1-like [KO:K13416] [EC:2.7.10.1 2.7.11.1]
101298672  elongation factor Tu, mitochondrial [KO:K02358]
101314086  elongation factor Tu, chloroplastic [KO:K02358]
101307721  elongation factor Tu, chloroplastic-like [KO:K02358]
101294665  mitogen-activated protein kinase kinase kinase 1-like [KO:K13414] [EC:2.7.11.25]
101299988  mitogen-activated protein kinase kinase 6 [KO:K04368] [EC:2.7.12.2]
101298915  mitogen-activated protein kinase kinase 5-like [KO:K13413] [EC:2.7.12.2]
101310632  mitogen-activated protein kinase kinase 5-like [KO:K13413] [EC:2.7.12.2]
101306313  mitogen-activated protein kinase 3 [KO:K20536] [EC:2.7.11.24]
101297368  mitogen-activated protein kinase homolog D5 [KO:K14512] [EC:2.7.11.24]
101305151  probable WRKY transcription factor 25 [KO:K13424]
101311683  probable WRKY transcription factor 33 [KO:K13424]
101304921  WRKY transcription factor 22 [KO:K13425]
101293392  probable WRKY transcription factor 29 [KO:K13426]
101314391  glycerol kinase-like [KO:K00864] [EC:2.7.1.30]
101307064  basic form of pathogenesis-related protein 1-like [KO:K13449]
101306986  pathogenesis-related protein 1-like [KO:K13449]
101298300  pathogenesis-related protein 1-like [KO:K13449]
101294126  pathogenesis-related protein 1A-like [KO:K13449]
101306697  basic form of pathogenesis-related protein 1-like [KO:K13449]
101307562  pathogenesis-related leaf protein 6-like [KO:K13449]
101306769  pathogenesis-related protein 1-like [KO:K13449]
101307351  pathogenesis-related protein 1B-like [KO:K13449]
101306185  pathogenesis-related protein 1A-like [KO:K13449]
101291611  pathogenesis-related genes transcriptional activator PTI6-like [KO:K13434]
101298506  PTI1-like tyrosine-protein kinase 3 [KO:K13436] [EC:2.7.11.1]
101311561  pto-interacting protein 1 [KO:K13436] [EC:2.7.11.1]
101293629  pto-interacting protein 1 [KO:K13436] [EC:2.7.11.1]
101308362  RPM1-interacting protein 4-like [KO:K13456]
101314524  RPM1-interacting protein 4 [KO:K13456]
101292850  NBS5; disease resistance protein RPM1-like [KO:K13457]
101314836  disease resistance protein RPM1-like [KO:K13457]
101290932  disease resistance protein RPM1-like [KO:K13457]
101313710  disease resistance protein RPM1-like [KO:K13457]
101312832  disease resistance protein RPM1-like [KO:K13457]
101314286  disease resistance protein RPM1-like [KO:K13457]
101313415  disease resistance protein RPM1-like [KO:K13457]
101313703  disease resistance protein RPM1-like [KO:K13457]
101314575  disease resistance protein RPM1-like [KO:K13457]
101296782  disease resistance protein RPM1-like [KO:K13457]
101313995  disease resistance protein RPM1-like [KO:K13457]
101314227  cysteine and histidine-rich domain-containing protein RAR1 [KO:K13458]
101303857  protein SGT1 homolog [KO:K12795]
101292873  heat shock protein 90-1 [KO:K09487]
101304351  endoplasmin homolog [KO:K09487]
101295509  heat shock protein 83 [KO:K09487]
101298691  heat shock protein 90-2 [KO:K04079]
101307057  heat shock protein 83-like [KO:K04079]
101307345  heat shock protein 83 [KO:K04079]
101303600  probable disease resistance protein At4g27220 [KO:K13459]
101313200  disease resistance protein At4g27190-like [KO:K13459]
101294724  serine/threonine-protein kinase PBS1 [KO:K13430] [EC:2.7.11.1]
101296987  serine/threonine-protein kinase CDL1 [KO:K13430] [EC:2.7.11.1]
101302655  protein EDS1B-like [KO:K18875]
101294426  cysteine proteinase 15A-like [KO:K01373] [EC:3.4.22.41]
101294030  probable cysteine proteinase A494 [KO:K01373] [EC:3.4.22.41]
101310260  cysteine proteinase 15A-like [KO:K01373] [EC:3.4.22.41]
101298755  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
101307175  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
101294912  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
101297691  3-ketoacyl-CoA synthase 10 [KO:K15397] [EC:2.3.1.199]
101305919  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
101312957  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
101307579  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
101293199  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
101312882  3-ketoacyl-CoA synthase 21-like [KO:K15397] [EC:2.3.1.199]
101298249  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
101313029  3-ketoacyl-CoA synthase 7 [KO:K15397] [EC:2.3.1.199]
101310169  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
101311234  3-ketoacyl-CoA synthase 21-like [KO:K15397] [EC:2.3.1.199]
101309137  3-ketoacyl-CoA synthase 12 [KO:K15397] [EC:2.3.1.199]
101313171  3-ketoacyl-CoA synthase 21-like [KO:K15397] [EC:2.3.1.199]
101291408  WRKY transcription factor 1 [KO:K18834]
101313293  probable WRKY transcription factor 2 [KO:K18835]
101307611  probable WRKY transcription factor 2 [KO:K18835]
101315391  probable LRR receptor-like serine/threonine-protein kinase At1g34110 [KO:K13466]
101293084  probable leucine-rich repeat receptor-like protein kinase At1g35710 [KO:K13466]
101299343  chitin elicitor receptor kinase 1-like [KO:K13429]
101302431  chitin elicitor receptor kinase 1-like [KO:K13429]
Compound
C00027  Hydrogen peroxide
C00076  Calcium cation
C00533  Nitric oxide
C00704  Superoxide
C16844  Hydroxyl radical
Reference
PMID:18206360
  Authors
Zipfel C
  Title
Pattern-recognition receptors in plant innate immunity.
  Journal
Curr Opin Immunol 20:10-6 (2008)
DOI:10.1016/j.coi.2007.11.003
Reference
PMID:19748302
  Authors
Chinchilla D, Shan L, He P, de Vries S, Kemmerling B
  Title
One for all: the receptor-associated kinase BAK1.
  Journal
Trends Plant Sci 14:535-41 (2009)
DOI:10.1016/j.tplants.2009.08.002
Reference
PMID:19423812
  Authors
Boller T, He SY
  Title
Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens.
  Journal
Science 324:742-4 (2009)
DOI:10.1126/science.1171647
Reference
PMID:19794842
  Authors
Ma W, Smigel A, Verma R, Berkowitz GA
  Title
Cyclic nucleotide gated channels and related signaling components in plant innate immunity.
  Journal
Plant Signal Behav 4:277-82 (2009)
DOI:10.4161/psb.4.4.8103
Reference
PMID:11875555
  Authors
Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J
  Title
MAP kinase signalling cascade in Arabidopsis innate immunity.
  Journal
Nature 415:977-83 (2002)
DOI:10.1038/415977a
Reference
PMID:15922649
  Authors
Zipfel C, Felix G
  Title
Plants and animals: a different taste for microbes?
  Journal
Curr Opin Plant Biol 8:353-60 (2005)
DOI:10.1016/j.pbi.2005.05.004
Reference
PMID:17451411
  Authors
He P, Shan L, Sheen J
  Title
Elicitation and suppression of microbe-associated molecular pattern-triggered immunity in plant-microbe interactions.
  Journal
Cell Microbiol 9:1385-96 (2007)
DOI:10.1111/j.1462-5822.2007.00944.x
Reference
PMID:17876517
  Authors
de Wit PJ
  Title
How plants recognize pathogens and defend themselves.
  Journal
Cell Mol Life Sci 64:2726-32 (2007)
DOI:10.1007/s00018-007-7284-7
Reference
PMID:16497589
  Authors
Chisholm ST, Coaker G, Day B, Staskawicz BJ
  Title
Host-microbe interactions: shaping the evolution of the plant immune response.
  Journal
Cell 124:803-14 (2006)
DOI:10.1016/j.cell.2006.02.008
Reference
PMID:16677430
  Authors
McHale L, Tan X, Koehl P, Michelmore RW
  Title
Plant NBS-LRR proteins: adaptable guards.
  Journal
Genome Biol 7:212 (2006)
DOI:10.1186/gb-2006-7-4-212
Reference
PMID:11459065
  Authors
Dangl JL, Jones JD
  Title
Plant pathogens and integrated defence responses to infection.
  Journal
Nature 411:826-33 (2001)
DOI:10.1038/35081161
Reference
PMID:17108957
  Authors
Jones JD, Dangl JL
  Title
The plant immune system.
  Journal
Nature 444:323-9 (2006)
DOI:10.1038/nature05286
Reference
PMID:16697674
  Authors
da Cunha L, McFall AJ, Mackey D
  Title
Innate immunity in plants: a continuum of layered defenses.
  Journal
Microbes Infect 8:1372-81 (2006)
DOI:10.1016/j.micinf.2005.12.018
Reference
PMID:15862106
  Authors
Mudgett MB
  Title
New insights to the function of phytopathogenic bacterial type III effectors in plants.
  Journal
Annu Rev Plant Biol 56:509-31 (2005)
DOI:10.1146/annurev.arplant.56.032604.144218
Reference
PMID:17714518
  Authors
Ma W, Berkowitz GA
  Title
The grateful dead: calcium and cell death in plant innate immunity.
  Journal
Cell Microbiol 9:2571-85 (2007)
DOI:10.1111/j.1462-5822.2007.01031.x
Reference
PMID:14711430
  Authors
Schulze-Lefert P
  Title
Plant immunity: the origami of receptor activation.
  Journal
Curr Biol 14:R22-4 (2004)
DOI:10.1016/j.cub.2003.12.017
Reference
PMID:9868361
  Authors
Van der Biezen EA, Jones JD
  Title
Plant disease-resistance proteins and the gene-for-gene concept.
  Journal
Trends Biochem Sci 23:454-6 (1998)
DOI:10.1016/S0968-0004(98)01311-5
Reference
PMID:16936700
  Authors
Abramovitch RB, Anderson JC, Martin GB
  Title
Bacterial elicitation and evasion of plant innate immunity.
  Journal
Nat Rev Mol Cell Biol 7:601-11 (2006)
DOI:10.1038/nrm1984
Related
pathway
fve04144  Endocytosis
KO pathway
ko04626   
LinkDB

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