KEGG   PATHWAY: hhy01230
Entry
hhy01230                    Pathway                                
Name
Biosynthesis of amino acids - Haliscomenobacter hydrossis
Description
This map presents a modular architecture of the biosynthesis pathways of twenty amino acids, which may be viewed as consisting of the core part and its extensions. The core part is the KEGG module for conversion of three-carbon compounds from glyceraldehyde-3P to pyruvate [MD:M00002], together with the pathways around serine and glycine. This KEGG module is the most conserved one in the KEGG MODULE database and is found in almost all the completely sequenced genomes. The extensions are the pathways containing the reaction modules RM001, RM033, RM032, and RM002 for biosynthesis of branched-chain amino acids (left) and basic amino acids (bottom), and the pathways for biosynthesis of histidine and aromatic amino acids (top right). It is interesting to note that the so-called essential amino acids that cannot be synthesized in human and other organisms generally appear in these extensions. Furthermore, the bottom extension of basic amino acids appears to be most divergent containing multiple pathways for lysine biosynthesis and multiple gene sets for arginine biosynthesis.
Class
Pathway map
hhy01230  Biosynthesis of amino acids
hhy01230

Module
hhy_M00002  Glycolysis, core module involving three-carbon compounds [PATH:hhy01230]
hhy_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hhy01230]
hhy_M00007  Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:hhy01230]
hhy_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:hhy01230]
hhy_M00015  Proline biosynthesis, glutamate => proline [PATH:hhy01230]
hhy_M00018  Threonine biosynthesis, aspartate => homoserine => threonine [PATH:hhy01230]
hhy_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:hhy01230]
hhy_M00023  Tryptophan biosynthesis, chorismate => tryptophan [PATH:hhy01230]
hhy_M00026  Histidine biosynthesis, PRPP => histidine [PATH:hhy01230]
hhy_M00338  Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:hhy01230]
hhy_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:hhy01230]
hhy_M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:hhy01230]
hhy_M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate [PATH:hhy01230]
Organism
Haliscomenobacter hydrossis [GN:hhy]
KO pathway
ko01230   
LinkDB

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