KEGG   PATHWAY: mex00230
Entry
mex00230                    Pathway                                
Name
Purine metabolism - Methylorubrum extorquens PA1
Class
Metabolism; Nucleotide metabolism
Pathway map
mex00230  Purine metabolism
mex00230

Module
mex_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mex00230]
mex_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mex00230]
mex_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mex00230]
mex_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mex00230]
mex_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:mex00230]
mex_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:mex00230]
Other DBs
GO: 0006163 0042278
Organism
Methylorubrum extorquens PA1 [GN:mex]
Gene
Mext_1934  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
Mext_2887  phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I [KO:K01835] [EC:5.4.2.2]
Mext_4125  phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I [KO:K15778] [EC:5.4.2.8 5.4.2.2]
Mext_3875  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Mext_3932  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Mext_3871  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Mext_2062  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Mext_0011  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
Mext_0598  phosphoribosylformylglycinamidine synthase, purS [KO:K23264] [EC:6.3.5.3]
Mext_0599  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Mext_2063  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Mext_1963  phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
Mext_1962  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
Mext_0587  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Mext_0996  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Mext_2566  phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Mext_0600  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Mext_1472  5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Mext_4233  stationary-phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Mext_2966  purine nucleotide phosphorylase [KO:K03783] [EC:2.4.2.1]
Mext_2883  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Mext_2861  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Mext_2939  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Mext_2012  Nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Mext_0402  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Mext_0837  aldehyde oxidase and xanthine dehydrogenase molybdopterin binding [KO:K11177] [EC:1.17.1.4]
Mext_3667  aldehyde oxidase and xanthine dehydrogenase molybdopterin binding [KO:K11177] [EC:1.17.1.4]
Mext_2815  aldehyde oxidase and xanthine dehydrogenase molybdopterin binding [KO:K11177] [EC:1.17.1.4]
Mext_0836  molybdopterin dehydrogenase FAD-binding [KO:K11178] [EC:1.17.1.4]
Mext_3666  molybdopterin dehydrogenase FAD-binding [KO:K11178] [EC:1.17.1.4]
Mext_2814  molybdopterin dehydrogenase FAD-binding [KO:K11178] [EC:1.17.1.4]
Mext_0835  (2Fe-2S)-binding domain protein [KO:K13483]
Mext_3665  (2Fe-2S)-binding domain protein [KO:K13483]
Mext_2813  (2Fe-2S)-binding domain protein [KO:K13483]
Mext_3437  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Mext_2931  GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
Mext_1727  guanine deaminase [KO:K01487] [EC:3.5.4.3]
Mext_3135  CMP/dCMP deaminase zinc-binding [KO:K01487] [EC:3.5.4.3]
Mext_2000  Guanylate kinase [KO:K00942] [EC:2.7.4.8]
Mext_1102  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
Mext_3393  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Mext_4306  metal-dependent phosphohydrolase HD sub domain [KO:K06952] [EC:3.1.3.89]
Mext_3018  metal-dependent phosphohydrolase HD sub domain [KO:K21138] [EC:3.1.7.2]
Mext_3196  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Mext_3433  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Mext_2068  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Mext_3188  adenylyl cyclase class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
Mext_0606  adenylyl cyclase class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
Mext_4777  adenylyl cyclase class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
Mext_3083  adenylyl cyclase class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
Mext_3082  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Mext_0521  adenylyl cyclase class-3/4/guanylyl cyclase [KO:K01768] [EC:4.6.1.1]
Mext_0999  Adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
Mext_0708  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Mext_3431  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
Mext_2362  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
Mext_2180  adenylate kinase [KO:K00939] [EC:2.7.4.3]
Mext_3913  MazG family protein [KO:K04765] [EC:3.6.1.9]
Mext_2232  sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
Mext_2233  sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
Mext_1745  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
Mext_3023  conserved hypothetical protein [KO:K07127] [EC:3.5.2.17]
Mext_1744  urate catabolism protein [KO:K16842] [EC:3.5.2.5]
Mext_1741  allantoin catabolism protein [KO:K14977] [EC:3.5.3.26]
Mext_1740  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Mext_1307  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Mext_1197  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Mext_3016  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Mext_1308  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
Mext_1309  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Mext_1196  urease, gamma subunit [KO:K14048] [EC:3.5.1.5]
Mext_3019  urease, gamma subunit [KO:K14048] [EC:3.5.1.5]
Mext_4849  gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Mext_1030  Gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mex00030  Pentose phosphate pathway
mex00220  Arginine biosynthesis
mex00250  Alanine, aspartate and glutamate metabolism
mex00260  Glycine, serine and threonine metabolism
mex00340  Histidine metabolism
mex00630  Glyoxylate and dicarboxylate metabolism
mex00730  Thiamine metabolism
mex00740  Riboflavin metabolism
mex00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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