Entry Name ABC transporters - Microlunatus phosphovorus
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Microlunatus phosphovorus [GN:
mph ]
Gene MLP_20390 subI; sulfate ABC transporter sulfate-binding protein [KO:K23163 ]
MLP_24260 modA; putative molybdate ABC transporter molybdate-binding protein [KO:K02020 ]
MLP_24250 modB; putative molybdate ABC transporter permease protein [KO:K02018 ]
MLP_10710 putative iron(III) ABC transporter iron(III)-binding protein [KO:K02012 ]
MLP_09990 opuAC; glycine betaine ABC transporter glycine betaine-binding protein [KO:K02002 ]
MLP_09980 opuAB; glycine betaine ABC transporter permease protein [KO:K02001 ]
MLP_05890 putative osmoprotectant ABC transporter substrate-binding protein [KO:K05845 ]
MLP_05870 putative osmoprotectant ABC transporter permease protein [KO:K05846 ]
MLP_05880 putative osmoprotectant ABC transporter permease protein [KO:K05846 ]
MLP_47090 msiK; multiple sugar ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
MLP_21770 putative sugar ABC transporter substrate-binding protein [KO:K10117 ]
MLP_07130 putative sugar ABC transporter substrate-binding protein [KO:K10227 ]
MLP_17340 putative sugar ABC transporter substrate-binding protein [KO:K10227 ]
MLP_38670 putative sugar ABC transporter substrate-binding protein [KO:K10232 ]
MLP_10780 putative sugar ABC transporter substrate-binding protein [KO:K10439 ]
MLP_47720 pstS; phosphate ABC transporter phosphate-binding protein [KO:K02040 ]
MLP_21200 gluB; glutamate ABC transporter glutamate-binding protein [KO:K10005 ]
MLP_20510 tcyA_tcyB; putative cystine ABC transporter cystine binding/permease protein [KO:K02424 K10009 ]
MLP_41130 branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999 ]
MLP_41120 livH; branched-chain amino acid ABC transporter permease protein [KO:K01997 ]
MLP_41110 livM; branched-chain amino acid ABC transporter permease protein [KO:K01998 ]
MLP_41100 livG; branched-chain amino acid ABC transporter ATP-binding protein [KO:K01995 ]
MLP_41090 livF; branched-chain amino acid ABC transporter ATP-binding protein [KO:K01996 ]
MLP_43340 putative peptide ABC transporter substrate-binding protein [KO:K15580 ]
MLP_49700 putative iron-siderophore ABC transporter substrate-binding protein [KO:K25287 ]
MLP_24780 putative metal ABC transporter substrate-binding protein [KO:K11601 ]
MLP_33890 putative metal ABC transporter substrate-binding protein [KO:K09815 ]
MLP_29360 putative ABC transporter ATP-binding protein [KO:K16784 ] [EC:7.6.2.-]
MLP_18350 putative ABC transporter permease/ATP-binding protein [KO:K14698 ] [EC:7.-.-.-]
MLP_18340 putative ABC transporter permease/ATP-binding protein [KO:K14699 ] [EC:7.-.-.-]
MLP_02500 putative ABC transporter permease/ATP-binding protein [KO:K18887 ]
MLP_02490 putative ABC transporter permease/ATP-binding protein [KO:K18888 ]
MLP_24640 cydC; putative ABC transporter permease/ATP-binding protein CydC [KO:K16012 ]
MLP_50510 putative ABC transporter permease/ATP-binding protein [KO:K16012 ]
MLP_24650 cydD; putative ABC transporter permease/ATP-binding protein CydD [KO:K16013 ]
MLP_50520 putative ABC transporter permease/ATP-binding protein [KO:K16013 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
