KEGG   PATHWAY: nto00350
Entry
nto00350                    Pathway                                
Name
Tyrosine metabolism - Nicotiana tomentosiformis
Class
Metabolism; Amino acid metabolism
Pathway map
nto00350  Tyrosine metabolism
nto00350

Module
nto_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:nto00350]
Other DBs
GO: 0006570
Organism
Nicotiana tomentosiformis [GN:nto]
Gene
104109843  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
104091393  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
104090398  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
104115756  aspartate aminotransferase, mitochondrial-like isoform X1 [KO:K14455] [EC:2.6.1.1]
104111195  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
104111606  bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase [KO:K15849] [EC:2.6.1.1 2.6.1.78 2.6.1.79]
104119618  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
104104119  tyrosine aminotransferase-like [KO:K00815] [EC:2.6.1.5]
104104136  tyrosine aminotransferase-like [KO:K00815] [EC:2.6.1.5]
104104148  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
104108282  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
104105751  histidinol-phosphate aminotransferase, chloroplastic isoform X1 [KO:K00817] [EC:2.6.1.9]
104084945  4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
104093200  LOW QUALITY PROTEIN: homogentisate 1,2-dioxygenase [KO:K00451] [EC:1.13.11.5]
104099590  glutathione S-transferase 2-like isoform X1 [KO:K01800] [EC:5.2.1.2]
104105521  glutathione S-transferase zeta class-like [KO:K01800] [EC:5.2.1.2]
104121032  fumarylacetoacetase [KO:K01555] [EC:3.7.1.2]
104085920  polyphenol oxidase E, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
104115752  polyphenol oxidase E, chloroplastic-like isoform X1 [KO:K00422] [EC:1.10.3.1]
104087343  polyphenol oxidase E, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
104118749  polyphenol oxidase E, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
104098486  polyphenol oxidase E, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
104109162  polyphenol oxidase E, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
104104551  polyphenol oxidase, chloroplastic-like [KO:K00422] [EC:1.10.3.1]
104113878  aromatic-L-amino-acid decarboxylase-like [KO:K01593] [EC:4.1.1.28 4.1.1.105]
104121182  tyrosine decarboxylase 1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
104090200  primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
104107599  primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
104092056  primary amine oxidase [KO:K00276] [EC:1.4.3.21]
104092059  LOW QUALITY PROTEIN: primary amine oxidase-like [KO:K00276] [EC:1.4.3.21]
104100798  uncharacterized protein LOC104100798 [KO:K00276] [EC:1.4.3.21]
104110987  uncharacterized protein LOC104110987 isoform X1 [KO:K00276] [EC:1.4.3.21]
104096221  uncharacterized protein LOC104096221 [KO:K00276] [EC:1.4.3.21]
104100122  alcohol dehydrogenase-like 7 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
104119691  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
104106353  alcohol dehydrogenase-like 7 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
104118260  alcohol dehydrogenase-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
104115832  alcohol dehydrogenase 1 [KO:K18857] [EC:1.1.1.1]
104090195  alcohol dehydrogenase 1 [KO:K18857] [EC:1.1.1.1]
104101051  alcohol dehydrogenase-like 4 [KO:K00001] [EC:1.1.1.1]
104116335  alcohol dehydrogenase-like 6 [KO:K00001] [EC:1.1.1.1]
104113653  acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
104101288  macrophage migration inhibitory factor homolog [KO:K07253] [EC:5.3.2.1]
104086153  macrophage migration inhibitory factor homolog [KO:K07253] [EC:5.3.2.1]
104093135  macrophage migration inhibitory factor homolog isoform X1 [KO:K07253] [EC:5.3.2.1]
104089553  hydroxyphenylpyruvate reductase [KO:K18606] [EC:1.1.1.237]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
nto00020  Citrate cycle (TCA cycle)
nto00360  Phenylalanine metabolism
nto00400  Phenylalanine, tyrosine and tryptophan biosynthesis
nto00620  Pyruvate metabolism
nto00650  Butanoate metabolism
nto00940  Phenylpropanoid biosynthesis
nto00950  Isoquinoline alkaloid biosynthesis
KO pathway
ko00350   
LinkDB

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