KEGG   PATHWAY: pcin01230
Entry
pcin01230                   Pathway                                
Name
Biosynthesis of amino acids - Prosopis cineraria
Description
This map presents a modular architecture of the biosynthesis pathways of twenty amino acids, which may be viewed as consisting of the core part and its extensions. The core part is the KEGG module for conversion of three-carbon compounds from glyceraldehyde-3P to pyruvate [MD:M00002], together with the pathways around serine and glycine. This KEGG module is the most conserved one in the KEGG MODULE database and is found in almost all the completely sequenced genomes. The extensions are the pathways containing the reaction modules RM001, RM033, RM032, and RM002 for biosynthesis of branched-chain amino acids (left) and basic amino acids (bottom), and the pathways for biosynthesis of histidine and aromatic amino acids (top right). It is interesting to note that the so-called essential amino acids that cannot be synthesized in human and other organisms generally appear in these extensions. Furthermore, the bottom extension of basic amino acids appears to be most divergent containing multiple pathways for lysine biosynthesis and multiple gene sets for arginine biosynthesis.
Class
Pathway map
pcin01230  Biosynthesis of amino acids
pcin01230

Module
pcin_M00002  Glycolysis, core module involving three-carbon compounds [PATH:pcin01230]
pcin_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pcin01230]
pcin_M00007  Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:pcin01230]
pcin_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:pcin01230]
pcin_M00015  Proline biosynthesis, glutamate => proline [PATH:pcin01230]
pcin_M00018  Threonine biosynthesis, aspartate => homoserine => threonine [PATH:pcin01230]
pcin_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:pcin01230]
pcin_M00020  Serine biosynthesis, glycerate-3P => serine [PATH:pcin01230]
pcin_M00021  Cysteine biosynthesis, serine => cysteine [PATH:pcin01230]
pcin_M00022  Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:pcin01230]
pcin_M00023  Tryptophan biosynthesis, chorismate => tryptophan [PATH:pcin01230]
pcin_M00028  Ornithine biosynthesis, glutamate => ornithine [PATH:pcin01230]
pcin_M00040  Tyrosine biosynthesis, chorismate => arogenate => tyrosine [PATH:pcin01230]
pcin_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:pcin01230]
pcin_M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:pcin01230]
pcin_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:pcin01230]
pcin_M00844  Arginine biosynthesis, ornithine => arginine [PATH:pcin01230]
pcin_M00910  Phenylalanine biosynthesis, chorismate => arogenate => phenylalanine [PATH:pcin01230]
Organism
Prosopis cineraria [GN:pcin]
KO pathway
ko01230   
LinkDB

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