KEGG   PATHWAY: pfor03083
Entry
pfor03083                   Pathway                                
Name
Polycomb repressive complex - Poecilia formosa (Amazon molly)
Class
Genetic Information Processing; Chromosome
Pathway map
pfor03083  Polycomb repressive complex
pfor03083

Organism
Poecilia formosa (Amazon molly) [GN:pfor]
Gene
103142220  histone-lysine N-methyltransferase EZH1 [KO:K17451] [EC:2.1.1.356]
103131053  ezh2; histone-lysine N-methyltransferase EZH2 [KO:K11430] [EC:2.1.1.356]
103139207  eed; polycomb protein EED [KO:K11462]
103137767  polycomb protein suz12-B-like [KO:K11463]
103146910  polycomb protein suz12-A-like [KO:K11463]
103136069  histone-binding protein RBBP4 [KO:K10752]
103129685  histone-binding protein RBBP7 isoform X1 [KO:K10752]
103152445  PHD finger protein 1 isoform X1 [KO:K11467]
103149533  mtf2; metal-response element-binding transcription factor 2 [KO:K11485]
103156295  phf19; LOW QUALITY PROTEIN: PHD finger protein 19 [KO:K11486]
103154496  ligand-dependent corepressor-like isoform X1 [KO:K26260]
103152531  zinc finger protein aebp2-like [KO:K17452]
103155451  aebp2; zinc finger protein AEBP2 isoform X2 [KO:K17452]
103135161  jarid2; protein Jumonji [KO:K11478]
103138034  bap1; ubiquitin carboxyl-terminal hydrolase BAP1 [KO:K08588] [EC:3.4.19.12]
103154225  putative Polycomb group protein ASXL1 isoform X1 [KO:K11471]
103148346  putative Polycomb group protein ASXL2 isoform X3 [KO:K11471]
103148347  putative Polycomb group protein ASXL2 isoform X1 [KO:K11471]
103148349  putative Polycomb group protein ASXL2 isoform X3 [KO:K11471]
103135630  ogt; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
103130748  host cell factor 1-like isoform X2 [KO:K14966]
103147348  hcfc1; host cell factor 1 [KO:K14966]
103144263  transcriptional repressor protein YY1 [KO:K09201]
103152658  transcriptional repressor protein YY1-like isoform X1 [KO:K09201]
103149470  mbd5; methyl-CpG-binding domain protein 5 isoform X1 [KO:K23219]
103139011  proline-rich protein 36-like [KO:K26585]
103144612  forkhead box protein K2-like [KO:K09404]
103154816  foxk1; forkhead box protein K1 isoform X2 [KO:K09404]
103155907  forkhead box protein K2-like [KO:K09404]
103129989  rnf2; E3 ubiquitin-protein ligase RING2 isoform X1 [KO:K10695] [EC:2.3.2.27]
103149753  ring1; E3 ubiquitin-protein ligase RING1 isoform X2 [KO:K10695] [EC:2.3.2.27]
103133453  pcgf2; polycomb group RING finger protein 2 [KO:K11460]
103135276  uncharacterized protein LOC103135276 [KO:K11459]
103146900  chromobox protein homolog 2 [KO:K11451]
103147077  chromobox protein homolog 2-like [KO:K11451]
103133063  cbx4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
103141632  E3 SUMO-protein ligase CBX4-like [KO:K11452] [EC:2.3.2.-]
103153429  polycomb group protein Pc-like [KO:K11454]
103143382  chromobox protein homolog 7-like [KO:K11454]
103133078  chromobox protein homolog 8 [KO:K11455]
103141633  chromobox protein homolog 8-like [KO:K11455]
103146439  polyhomeotic-like protein 1 isoform X2 [KO:K11456]
103136714  phc1; polyhomeotic-like protein 1 [KO:K11456]
103134625  polyhomeotic-like protein 2 isoform X1 [KO:K11457]
103154236  polyhomeotic-like protein 2 isoform X2 [KO:K11457]
103131050  polyhomeotic-like protein 3 isoform X5 [KO:K11458]
103143566  polycomb protein SCMH1-like isoform X1 [KO:K11465]
103137157  scml2; sex comb on midleg-like protein 2 isoform X3 [KO:K11465]
103141572  polycomb protein SCMH1-like isoform X2 [KO:K11461]
103129569  sfmbt2; scm-like with four MBT domains protein 2 [KO:K26269]
103145766  sfmbt1; scm-like with four MBT domains protein 1 isoform X1 [KO:K26269]
103149571  aurora kinase B-like [KO:K11479] [EC:2.7.11.1]
103149574  aurora kinase B-like [KO:K11479] [EC:2.7.11.1]
103131211  ube2d3; ubiquitin-conjugating enzyme E2 D3 [KO:K06689] [EC:2.3.2.23]
103146202  ubiquitin-conjugating enzyme E2 D4 isoform X2 [KO:K06689] [EC:2.3.2.23]
103133599  ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
103149268  ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
103150060  ubiquitin-conjugating enzyme E2 D2-like isoform X2 [KO:K06689] [EC:2.3.2.23]
103150922  usp45; ubiquitin carboxyl-terminal hydrolase 45 [KO:K11844] [EC:3.4.19.12]
103149437  usp16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 [KO:K11844] [EC:3.4.19.12]
103130385  rybp; RING1 and YY1-binding protein isoform X2 [KO:K11469]
103134431  YY1-associated factor 2-like isoform X1 [KO:K11468]
103156810  yaf2; YY1-associated factor 2 isoform X2 [KO:K11468]
103137303  pcgf1; polycomb group RING finger protein 1 isoform X1 [KO:K11487]
103146746  lysine-specific demethylase 2B-like isoform X1 [KO:K10276] [EC:1.14.11.27]
103153626  lysine-specific demethylase 2A-like isoform X1 [KO:K10276] [EC:1.14.11.27]
103153631  lysine-specific demethylase 2A-like isoform X1 [KO:K10276] [EC:1.14.11.27]
103147495  kdm2a; lysine-specific demethylase 2A [KO:K10276] [EC:1.14.11.27]
103148830  lysine-specific demethylase 2B-like isoform X2 [KO:K10276] [EC:1.14.11.27]
103134720  bcor; BCL-6 corepressor isoform X1 [KO:K23215]
103150175  bcorl1; BCL-6 corepressor-like protein 1 isoform X2 [KO:K26199]
103155759  skp1; S-phase kinase-associated protein 1 [KO:K03094]
103147419  usp7; ubiquitin carboxyl-terminal hydrolase 7 isoform X3 [KO:K11838] [EC:3.4.19.12]
103152187  pcgf3; polycomb group RING finger protein 3 [KO:K11488]
103149001  pcgf5; polycomb group RING finger protein 5 isoform X1 [KO:K11489]
103154558  casein kinase II subunit beta [KO:K03115]
103143079  casein kinase II subunit beta-like [KO:K03115]
103142101  auts2; autism susceptibility gene 2 protein isoform X1 [KO:K23214]
103152251  autism susceptibility gene 2 protein-like isoform X1 [KO:K26253]
103141348  autism susceptibility gene 2 protein isoform X2 [KO:K26254]
103144990  dcaf7; DDB1- and CUL4-associated factor 7 [KO:K11805]
103140866  tex10; testis-expressed sequence 10 protein [KO:K14827]
103131032  CREB-binding protein-like isoform X1 [KO:K04498] [EC:2.3.1.48]
103143377  histone acetyltransferase p300-like [KO:K04498] [EC:2.3.1.48]
103141005  CREB-binding protein-like isoform X5 [KO:K04498] [EC:2.3.1.48]
103153459  histone acetyltransferase p300-like [KO:K04498] [EC:2.3.1.48]
103154930  pcgf6; polycomb group RING finger protein 6 [KO:K11470]
103146769  transcription factor E2F6-like [KO:K09390]
103156400  transcription factor E2F6-like isoform X2 [KO:K09390]
103140332  tfdp1; transcription factor Dp-1 [KO:K04683]
103130525  max; protein max isoform X1 [KO:K04453]
103136133  protein max-like [KO:K04453]
103133029  MAX gene-associated protein-like isoform X1 [KO:K23399]
103153855  uncharacterized protein LOC103153855 isoform X1 [KO:K23399]
103156037  lethal(3)malignant brain tumor-like protein 1 isoform X1 [KO:K24387]
103144800  l3mbtl2; lethal(3)malignant brain tumor-like protein 2 [KO:K24387]
103140849  l3mbtl3; lethal(3)malignant brain tumor-like protein 3 [KO:K24387]
103154859  lethal(3)malignant brain tumor-like protein 1 [KO:K24387]
103154861  lethal(3)malignant brain tumor-like protein 4 isoform X1 [KO:K24387]
103145272  chromobox protein homolog 3 isoform X2 [KO:K11586]
103150371  chromobox protein homolog 3-like [KO:K11586]
103144569  WD repeat-containing protein 5 [KO:K14963]
103144573  WD repeat-containing protein 5 [KO:K14963]
103150870  hdac2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
103146042  probable histone deacetylase 1-B [KO:K06067] [EC:3.5.1.98]
103153388  probable histone deacetylase 1-B [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
LinkDB

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