KEGG   PATHWAY: pmai01230
Entry
pmai01230                   Pathway                                
Name
Biosynthesis of amino acids - Paraphotobacterium marinum
Description
This map presents a modular architecture of the biosynthesis pathways of twenty amino acids, which may be viewed as consisting of the core part and its extensions. The core part is the KEGG module for conversion of three-carbon compounds from glyceraldehyde-3P to pyruvate [MD:M00002], together with the pathways around serine and glycine. This KEGG module is the most conserved one in the KEGG MODULE database and is found in almost all the completely sequenced genomes. The extensions are the pathways containing the reaction modules RM001, RM033, RM032, and RM002 for biosynthesis of branched-chain amino acids (left) and basic amino acids (bottom), and the pathways for biosynthesis of histidine and aromatic amino acids (top right). It is interesting to note that the so-called essential amino acids that cannot be synthesized in human and other organisms generally appear in these extensions. Furthermore, the bottom extension of basic amino acids appears to be most divergent containing multiple pathways for lysine biosynthesis and multiple gene sets for arginine biosynthesis.
Class
Pathway map
pmai01230  Biosynthesis of amino acids
pmai01230

Module
pmai_M00007  Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:pmai01230]
pmai_M00015  Proline biosynthesis, glutamate => proline [PATH:pmai01230]
pmai_M00018  Threonine biosynthesis, aspartate => homoserine => threonine [PATH:pmai01230]
pmai_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:pmai01230]
pmai_M00020  Serine biosynthesis, glycerate-3P => serine [PATH:pmai01230]
pmai_M00021  Cysteine biosynthesis, serine => cysteine [PATH:pmai01230]
pmai_M00022  Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:pmai01230]
pmai_M00023  Tryptophan biosynthesis, chorismate => tryptophan [PATH:pmai01230]
pmai_M00028  Ornithine biosynthesis, glutamate => ornithine [PATH:pmai01230]
pmai_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:pmai01230]
pmai_M00844  Arginine biosynthesis, ornithine => arginine [PATH:pmai01230]
Organism
Paraphotobacterium marinum [GN:pmai]
KO pathway
ko01230   
LinkDB

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