KEGG   PATHWAY: ppno02010
Entry
ppno02010                   Pathway                                
Name
ABC transporters - Pandoraea pnomenusa RB38
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
ppno02010  ABC transporters
ppno02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Pandoraea pnomenusa RB38 [GN:ppno]
Gene
DA70_05670  sulfate transporter subunit [KO:K23163]
DA70_05665  sulfate ABC transporter permease subunit CysT [KO:K02046]
DA70_05660  sulfate ABC transporter permease subunit CysW [KO:K02047]
DA70_05655  sulfate ABC transporter ATP-binding protein [KO:K02045] [EC:7.3.2.3]
DA70_12700  taurine ABC transporter substrate-binding protein [KO:K15551]
DA70_03660  taurine ABC transporter substrate-binding protein [KO:K15551]
DA70_00345  taurine ABC transporter substrate-binding protein [KO:K15551]
DA70_12710  taurine ABC transporter permease [KO:K15552]
DA70_03655  ABC transporter permease [KO:K15552]
DA70_12705  nitrate ABC transporter ATP-binding protein [KO:K10831] [EC:7.6.2.7]
DA70_07585  ABC transporter substrate-binding protein [KO:K15553]
DA70_16950  nitrate ABC transporter substrate-binding protein [KO:K15553]
DA70_22255  hypothetical protein [KO:K15553]
DA70_06450  ABC transporter substrate-binding protein [KO:K15553]
DA70_21075  nitrate ABC transporter substrate-binding protein [KO:K15553]
DA70_16960  ABC transporter permease [KO:K15554]
DA70_21080  ABC transporter permease [KO:K15554]
DA70_06435  ABC transporter permease [KO:K15554]
DA70_22250  hypothetical protein [KO:K15554]
DA70_22245  hypothetical protein [KO:K15555] [EC:7.6.2.14]
DA70_21085  ABC transporter [KO:K15555] [EC:7.6.2.14]
DA70_06445  mannosyltransferase [KO:K15555] [EC:7.6.2.14]
DA70_16955  mannosyltransferase [KO:K15555] [EC:7.6.2.14]
DA70_23175  molybdate ABC transporter substrate-binding protein [KO:K02020]
DA70_23440  molybdenum ABC transporter substrate-binding protein [KO:K02020]
DA70_23170  molybdate ABC transporter permease [KO:K02018]
DA70_23165  hypothetical protein [KO:K02017] [EC:7.3.2.5]
DA70_13425  putative 2-aminoethylphosphonate ABC transporter substrate-binding protein [KO:K02012]
DA70_10945  ABC transporter substrate-binding protein [KO:K02012]
DA70_06545  Fe(3+) ABC transporter substrate-binding protein [KO:K02012]
DA70_13435  phosphonate ABC transporter permease [KO:K02011]
DA70_07600  iron ABC transporter permease [KO:K02011]
DA70_10950  ABC transporter permease [KO:K02011]
DA70_13430  amino acid ABC transporter substrate-binding protein [KO:K02010] [EC:7.2.2.7]
DA70_07605  ABC transporter ATP-binding protein [KO:K02010] [EC:7.2.2.7]
DA70_10940  ABC transporter substrate-binding protein [KO:K02010] [EC:7.2.2.7]
DA70_00780  glycine betaine ABC transporter substrate-binding protein [KO:K02002]
DA70_00785  glycine/betaine ABC transporter permease [KO:K02001]
DA70_00790  proline/glycine betaine ABC transporter ATP-binding protein [KO:K02000] [EC:7.6.2.9]
DA70_19635  glycine/betaine ABC transporter substrate-binding protein [KO:K05845]
DA70_19640  choline ABC transporter permease [KO:K05846]
DA70_19630  glycine/betaine ABC transporter permease [KO:K05846]
DA70_19645  glycine/betaine ABC transporter ATP-binding protein [KO:K05847] [EC:7.6.2.9]
DA70_18200  hypothetical protein [KO:K07323]
DA70_09060  ABC transporter [KO:K07323]
DA70_14105  ABC transporter substrate-binding protein [KO:K02067]
DA70_18190  outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067]
DA70_14115  ABC transporter permease [KO:K02066]
DA70_18185  ABC transporter permease [KO:K02066]
DA70_18205  hypothetical protein [KO:K07122]
DA70_14110  ABC transporter ATP-binding protein [KO:K02065]
DA70_18180  ABC transporter ATP-binding protein [KO:K02065]
DA70_05025  hypothetical protein [KO:K07335]
DA70_05035  sugar ABC transporter permease [KO:K23535]
DA70_05030  ABC transporter permease [KO:K23536]
DA70_05040  ABC transporter [KO:K23537]
DA70_08575  ABC transporter substrate-binding protein [KO:K05813]
DA70_21860  glycerol-3-phosphate ABC transporter substrate-binding protein [KO:K05813]
DA70_08570  ABC transporter permease [KO:K05814]
DA70_21855  glycerol-3-phosphate transporter permease [KO:K05814]
DA70_08565  ABC transporter permease [KO:K05815]
DA70_21850  glycerol-3-phosphate transporter [KO:K05815]
DA70_21845  glycerol-3-phosphate ABC transporter ATP-binding protein [KO:K05816] [EC:7.6.2.10]
DA70_00155  phosphate ABC transporter substrate-binding protein [KO:K02040]
DA70_00160  pstC; phosphate transporter permease subunit PstC [KO:K02037]
DA70_00165  pstA; phosphate transporter permease subunit PtsA [KO:K02038]
DA70_00170  phosphate ABC transporter ATP-binding protein [KO:K02036] [EC:7.3.2.1]
DA70_13530  phosphonate ABC transporter substrate-binding protein [KO:K02044]
DA70_13520  phosphonate ABC transporter, permease protein PhnE [KO:K02042]
DA70_13535  phosphonate ABC transporter ATP-binding protein [KO:K02041] [EC:7.3.2.2]
DA70_12315  ABC transporter [KO:K10001]
DA70_14810  ABC transporter [KO:K10001]
DA70_12305  amino acid ABC transporter permease [KO:K10002]
DA70_12310  amino acid ABC transporter permease [KO:K10003]
DA70_12300  artP; arginine transporter ATP-binding subunit [KO:K10004] [EC:7.4.2.1]
DA70_06220  cysteine ABC transporter substrate-binding protein [KO:K02424]
DA70_06225  ABC transporter permease [KO:K10009]
DA70_14185  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_15740  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_15125  ABC transporter substrate-binding protein [KO:K01999]
DA70_08350  ABC transporter permease [KO:K01999]
DA70_11655  ethanolamine utilization protein EutN [KO:K01999]
DA70_08125  ABC transporter permease [KO:K01999]
DA70_07645  ABC transporter substrate-binding protein [KO:K01999]
DA70_10745  leucine ABC transporter subunit substrate-binding protein LivK [KO:K01999]
DA70_10400  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_03440  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_04755  amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_23525  ABC transporter substrate-binding protein [KO:K01999]
DA70_01315  ABC transporter permease [KO:K01999]
DA70_00520  ABC transporter substrate-binding protein [KO:K01999]
DA70_23990  ABC transporter substrate-binding protein [KO:K01999]
DA70_17035  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_16550  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_16525  ABC transporter permease [KO:K01999]
DA70_21495  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_20085  ABC transporter permease [KO:K01999]
DA70_22925  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_01440  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_01760  ABC transporter permease [KO:K01999]
DA70_15120  ABC transporter permease [KO:K01997]
DA70_15745  ABC transporter permease [KO:K01997]
DA70_11660  ABC transporter permease [KO:K01997]
DA70_08105  ABC transporter permease [KO:K01997]
DA70_07640  ABC transporter permease [KO:K01997]
DA70_10750  branched-chain amino acid transporter permease subunit LivH [KO:K01997]
DA70_04750  ABC transporter permease [KO:K01997]
DA70_23520  ABC transporter permease [KO:K01997]
DA70_01305  ABC transporter permease [KO:K01997]
DA70_00525  branched-chain amino acid ABC transporter permease [KO:K01997]
DA70_23980  ABC transporter permease [KO:K01997]
DA70_16560  ABC transporter permease [KO:K01997]
DA70_16530  ABC transporter permease [KO:K01997]
DA70_21500  ABC transporter permease [KO:K01997]
DA70_22930  ABC transporter permease [KO:K01997]
DA70_04745  ABC transporter [KO:K01995 K01998]
DA70_16565  hypothetical protein [KO:K01995 K01998]
DA70_22935  hypothetical protein [KO:K01995 K01998]
DA70_11665  ABC transporter [KO:K01995 K01996 K01998]
DA70_15115  ABC transporter permease [KO:K01998]
DA70_15750  ABC transporter permease [KO:K01998]
DA70_08100  ABC transporter permease [KO:K01998]
DA70_07635  amino acid ABC transporter [KO:K01998]
DA70_10755  livM; branched-chain amino acid ABC transporter permease [KO:K01998]
DA70_02935  ABC transporter permease [KO:K01998]
DA70_01310  ABC transporter permease [KO:K01998]
DA70_23975  ABC transporter permease [KO:K01998]
DA70_21505  ABC transporter ATP-binding protein [KO:K01998]
DA70_16535  ABC transporter permease [KO:K01998]
DA70_15110  ABC transporter ATP-binding protein [KO:K01995]
DA70_24685  ABC transporter ATP-binding protein [KO:K01995]
DA70_08115  ABC transporter ATP-binding protein [KO:K01995]
DA70_07630  ABC transporter ATP-binding protein [KO:K01995]
DA70_10760  livG; ABC transporter ATP-binding protein [KO:K01995]
DA70_02940  ABC transporter ATP-binding protein [KO:K01995]
DA70_23510  ABC transporter ATP-binding protein [KO:K01995]
DA70_01300  ABC transporter ATP-binding protein [KO:K01995]
DA70_00535  ABC transporter ATP-binding protein [KO:K01995]
DA70_23970  ABC transporter ATP-binding protein [KO:K01995]
DA70_16515  ABC transporter ATP-binding protein [KO:K01995]
DA70_21510  ABC transporter ATP-binding protein [KO:K01995]
DA70_15105  ABC transporter ATP-binding protein [KO:K01996]
DA70_15760  ABC transporter ATP-binding protein [KO:K01996]
DA70_08110  ABC transporter ATP-binding protein [KO:K01996]
DA70_07625  ABC transporter ATP-binding protein [KO:K01996]
DA70_10765  livF; ABC transporter ATP-binding protein [KO:K01996]
DA70_04740  ABC transporter ATP-binding protein [KO:K01996]
DA70_02945  ABC transporter ATP-binding protein [KO:K01996]
DA70_22940  ABC transporter ATP-binding protein [KO:K01996]
DA70_23505  ABC transporter ATP-binding protein [KO:K01996]
DA70_01320  ABC transporter ATP-binding protein [KO:K01996]
DA70_00540  livF; ABC transporter ATP-binding protein [KO:K01996]
DA70_23965  ABC transporter ATP-binding protein [KO:K01996]
DA70_21515  ABC transporter ATP-binding protein [KO:K01996]
DA70_16570  ABC transporter ATP-binding protein [KO:K01996]
DA70_16520  ABC transporter ATP-binding protein [KO:K01996]
DA70_10825  metal ABC transporter substrate-binding protein [KO:K02073]
DA70_01035  metal ABC transporter substrate-binding protein [KO:K02073]
DA70_10830  DL-methionine transporter permease subunit [KO:K02072]
DA70_10835  phosphate ABC transporter ATP-binding protein [KO:K02071]
DA70_14880  urea ABC transporter substrate-binding protein [KO:K11959]
DA70_14885  urea ABC transporter permease subunit UrtB [KO:K11960]
DA70_14890  urea ABC transporter permease subunit UrtC [KO:K11961]
DA70_14895  ABC transporter ATP-binding protein [KO:K11962]
DA70_14900  ABC transporter ATP-binding protein [KO:K11963]
DA70_14990  peptide ABC transporter substrate-binding protein [KO:K12368]
DA70_01000  peptide ABC transporter substrate-binding protein [KO:K12368]
DA70_14985  peptide ABC transporter permease [KO:K12369]
DA70_14980  peptide transporter [KO:K12370]
DA70_14975  dppD; peptide ABC transporter ATP-binding protein [KO:K12371]
DA70_14970  peptide ABC transporter ATP-binding protein [KO:K12372]
DA70_08615  glutathione ABC transporter substrate-binding protein [KO:K13889]
DA70_08610  glutathione ABC transporter permease [KO:K13890]
DA70_08605  glutathione ABC transporter permease [KO:K13891]
DA70_08620  glutathione ABC transporter ATP-binding protein [KO:K13892]
DA70_06575  peptide ABC transporter substrate-binding protein [KO:K13893]
DA70_06570  microcin ABC transporter permease [KO:K13894]
DA70_06565  peptide ABC transporter permease [KO:K13895]
DA70_06560  microcin ABC transporter ATP-binding protein [KO:K13896]
DA70_08200  hypothetical protein [KO:K23227]
DA70_08195  Fe3+-hydroxamate ABC transporter permease FhuB [KO:K23228]
DA70_08185  iron-hydroxamate transporter ATP-binding subunit [KO:K10829] [EC:7.2.2.16]
DA70_13685  nodulation protein NodJ [KO:K09694]
DA70_13680  nodulation factor ABC transporter ATP-binding protein NodI [KO:K09695]
DA70_07195  cell division protein FtsX [KO:K09808]
DA70_07190  lipoprotein ABC transporter ATP-binding protein [KO:K09810] [EC:7.6.2.-]
DA70_10345  LPS export ABC transporter permease LptF [KO:K07091]
DA70_10350  LPS export ABC transporter permease LptG [KO:K11720]
DA70_13580  ABC transporter ATP-binding protein [KO:K06861] [EC:7.5.2.5]
DA70_21800  lipid ABC transporter permease/ATP-binding protein [KO:K11085] [EC:7.5.2.6]
DA70_12330  metal ABC transporter permease [KO:K24821]
DA70_09245  macrolide ABC transporter permease/ATP-binding protein MacB [KO:K05685] [EC:7.6.2.-]
DA70_08190  cyclic peptide transporter [KO:K06160]
DA70_18150  ABC transporter ATP-binding protein [KO:K02471]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
PMID:18424520
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
PMID:18375759
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
PMID:10557362
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
PMID:11731493
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
PMID:16135226
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
PMID:11929526
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
PMID:18326572
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
PMID:16109926
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
PMID:17873039
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
PMID:17214741
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
PMID:18805970
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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