KEGG   PATHWAY: rbb04612
Entry
rbb04612                    Pathway                                
Name
Antigen processing and presentation - Rhinopithecus bieti (black snub-nosed monkey)
Class
Organismal Systems; Immune system
Pathway map
rbb04612  Antigen processing and presentation
rbb04612

Other DBs
GO: 0019885 0019886 0042591
Organism
Rhinopithecus bieti (black snub-nosed monkey) [GN:rbb]
Gene
108532274  IFNG; LOW QUALITY PROTEIN: interferon gamma [KO:K04687]
108520255  TNF; tumor necrosis factor isoform X1 [KO:K03156]
108540932  PSME1; proteasome activator complex subunit 1 isoform X1 [KO:K06696]
108540935  PSME2; proteasome activator complex subunit 2 isoform X1 [KO:K06697]
108526776  PSME3; proteasome activator complex subunit 3 isoform X1 [KO:K06698]
108520227  heat shock 70 kDa protein 1 [KO:K03283]
108520228  heat shock 70 kDa protein 1-like [KO:K03283]
108531954  HSPA8; LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein [KO:K03283]
108528791  heat shock cognate 71 kDa protein [KO:K03283]
108542584  HSPA6; LOW QUALITY PROTEIN: heat shock 70 kDa protein 6 [KO:K03283]
108542412  HSPA2; LOW QUALITY PROTEIN: heat shock-related 70 kDa protein 2 [KO:K26598]
108529570  HSPA4; LOW QUALITY PROTEIN: heat shock 70 kDa protein 4 [KO:K09489]
108542298  HSP90AA1; LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha [KO:K04079]
108533442  HSP90AB1; LOW QUALITY PROTEIN: heat shock protein HSP 90-beta [KO:K04079]
108537061  LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha-like [KO:K04079]
108543093  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like [KO:K06751]
108543097  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1 [KO:K06751]
108525667  HLA class I histocompatibility antigen, B-38 alpha chain isoform X1 [KO:K06751]
108528429  mamu class I histocompatibility antigen, alpha chain F [KO:K06751]
108528432  saoe class I histocompatibility antigen, C alpha chain-like isoform X1 [KO:K06751]
108528436  HLA class I histocompatibility antigen, A-11 alpha chain isoform X1 [KO:K06751]
108522562  popy class I histocompatibility antigen, alpha chain E isoform X1 [KO:K06751]
108531361  HSPA5; 78 kDa glucose-regulated protein [KO:K09490] [EC:3.6.4.10]
108523361  CANX; calnexin [KO:K08054]
108521289  B2M; beta-2-microglobulin isoform X1 [KO:K08055]
108521293  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
108544097  CALR; calreticulin [KO:K08057]
108531812  LOW QUALITY PROTEIN: calreticulin-like [KO:K08057]
108540276  TAPBP; tapasin isoform X1 [KO:K08058]
108512976  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
108512981  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
108518880  CD8A; T-cell surface glycoprotein CD8 alpha chain isoform X1 [KO:K06458]
108518881  CD8B; T-cell surface glycoprotein CD8 beta chain isoform X1 [KO:K06459]
108522013  killer cell immunoglobulin-like receptor 3DS1 isoform X1 [KO:K07980]
108522014  killer cell immunoglobulin-like receptor 3DL2 [KO:K07980]
108518726  killer cell immunoglobulin-like receptor 3DL3 isoform X1 [KO:K07980]
108521201  putative killer cell immunoglobulin-like receptor-like protein KIR3DX1 [KO:K07980]
108521206  putative killer cell immunoglobulin-like receptor-like protein KIR3DX1 [KO:K07980]
108542130  NKG2-A/NKG2-B type II integral membrane protein-like [KO:K06541]
108542146  LOW QUALITY PROTEIN: NKG2-C type II integral membrane protein-like [KO:K24233]
108542145  NKG2-F type II integral membrane protein-like [KO:K24234]
108542154  KLRD1; natural killer cells antigen CD94 isoform X1 [KO:K06516]
108534224  IFI30; gamma-interferon-inducible lysosomal thiol reductase [KO:K08059]
108519101  LGMN; legumain [KO:K01369] [EC:3.4.22.34]
108536689  CTSB; cathepsin B isoform X1 [KO:K01363] [EC:3.4.22.1]
108540290  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
108540291  HLA class II histocompatibility antigen, DP beta 1 chain [KO:K06752]
108540294  HLA class II histocompatibility antigen, DP alpha 1 chain [KO:K06752]
108512973  HLA class II histocompatibility antigen, DM beta chain isoform X1 [KO:K06752]
108512974  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
108512982  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
108512983  HLA class II histocompatibility antigen, DQ beta 1 chain [KO:K06752]
108512984  HLA class II histocompatibility antigen, DQ alpha 1 chain [KO:K06752]
108512985  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
108519881  mamu class II histocompatibility antigen, DR alpha chain [KO:K06752]
108519884  HLA class II histocompatibility antigen, DRB1-13 beta chain isoform X1 [KO:K06752]
108519885  HLA class II histocompatibility antigen, DR beta 5 chain [KO:K06752]
108532043  CD74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
108521156  CTSL; cathepsin L1 [KO:K01365] [EC:3.4.22.15]
108543421  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
108521151  LOW QUALITY PROTEIN: putative inactive cathepsin L-like protein CTSL3P [KO:K01365] [EC:3.4.22.15]
108533262  CTSS; cathepsin S [KO:K01368] [EC:3.4.22.27]
108542050  CD4; T-cell surface glycoprotein CD4 isoform X1 [KO:K06454]
108541217  CIITA; LOW QUALITY PROTEIN: MHC class II transactivator [KO:K08060] [EC:2.7.11.1]
108533234  RFX5; DNA-binding protein RFX5 [KO:K08061]
108515646  RFXANK; DNA-binding protein RFXANK isoform X1 [KO:K08062]
108516591  RFXAP; regulatory factor X-associated protein [KO:K08063]
108540349  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
108528378  NFYA; nuclear transcription factor Y subunit alpha isoform X1 [KO:K08064]
108544257  NFYB; nuclear transcription factor Y subunit beta [KO:K08065]
108530393  NFYC; nuclear transcription factor Y subunit gamma isoform X1 [KO:K08066]
Reference
PMID:15771591
  Authors
Trombetta ES, Mellman I.
  Title
Cell biology of antigen processing in vitro and in vivo.
  Journal
Annu Rev Immunol 23:975-1028 (2005)
DOI:10.1146/annurev.immunol.22.012703.104538
Reference
PMID:15814328
  Authors
Inaba K, Inaba M.
  Title
Antigen recognition and presentation by dendritic cells.
  Journal
Int J Hematol 81:181-7 (2005)
DOI:10.1532/IJH97.04200
Reference
PMID:11905820
  Authors
Heath WR, Carbone FR.
  Title
Cross-presentation in viral immunity and self-tolerance.
  Journal
Nat Rev Immunol 1:126-34 (2001)
DOI:10.1038/35100512
Reference
PMID:15304636
  Authors
Abele R, Tampe R.
  Title
The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing.
  Journal
Physiology (Bethesda) 19:216-24 (2004)
DOI:10.1152/physiol.00002.2004
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:12776207
  Authors
Honey K, Rudensky AY.
  Title
Lysosomal cysteine proteases regulate antigen presentation.
  Journal
Nat Rev Immunol 3:472-82 (2003)
DOI:10.1038/nri1110
Reference
PMID:12974477
  Authors
Sercarz EE, Maverakis E.
  Title
Mhc-guided processing: binding of large antigen fragments.
  Journal
Nat Rev Immunol 3:621-9 (2003)
DOI:10.1038/nri1149
Reference
PMID:15224093
  Authors
Ackerman AL, Cresswell P.
  Title
Cellular mechanisms governing cross-presentation of exogenous antigens.
  Journal
Nat Immunol 5:678-84 (2004)
DOI:10.1038/ni1082
Reference
PMID:16181333
  Authors
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA.
  Title
Mechanisms of MHC class I-restricted antigen processing and cross-presentation.
  Journal
Immunol Rev 207:145-57 (2005)
DOI:10.1111/j.0105-2896.2005.00316.x
Reference
PMID:15653312
  Authors
Zika E, Ting JP.
  Title
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
  Journal
Curr Opin Immunol 17:58-64 (2005)
DOI:10.1016/j.coi.2004.11.008
Reference
PMID:11244040
  Authors
Reith W, Mach B.
  Title
The bare lymphocyte syndrome and the regulation of MHC expression.
  Journal
Annu Rev Immunol 19:331-73 (2001)
DOI:10.1146/annurev.immunol.19.1.331
Reference
PMID:15745856
  Authors
Lizee G, Basha G, Jefferies WA.
  Title
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation.
  Journal
Trends Immunol 26:141-9 (2005)
DOI:10.1016/j.it.2005.01.005
Reference
PMID:15224094
  Authors
Watts C.
  Title
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.
  Journal
Nat Immunol 5:685-92 (2004)
DOI:10.1038/ni1088
Reference
PMID:15653315
  Authors
Kaufmann SH, Schaible UE.
  Title
Antigen presentation and recognition in bacterial infections.
  Journal
Curr Opin Immunol 17:79-87 (2005)
DOI:10.1016/j.coi.2004.12.004
Reference
PMID:20010787
  Authors
Groettrup M, Kirk CJ, Basler M
  Title
Proteasomes in immune cells: more than peptide producers?
  Journal
Nat Rev Immunol 10:73-8 (2010)
DOI:10.1038/nri2687
Related
pathway
rbb03050  Proteasome
rbb04650  Natural killer cell mediated cytotoxicity
rbb04660  T cell receptor signaling pathway
KO pathway
ko04612   
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