KEGG   PATHWAY: rlg00230
Entry
rlg00230                    Pathway                                
Name
Purine metabolism - Rhizobium leguminosarum bv. trifolii WSM1325
Class
Metabolism; Nucleotide metabolism
Pathway map
rlg00230  Purine metabolism
rlg00230

Module
rlg_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rlg00230]
rlg_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rlg00230]
rlg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rlg00230]
rlg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rlg00230]
rlg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rlg00230]
rlg_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rlg00230]
rlg_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rlg00230]
Other DBs
GO: 0006163 0042278
Organism
Rhizobium leguminosarum bv. trifolii WSM1325 [GN:rlg]
Gene
Rleg_0055  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Rleg_6067  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Rleg_4469  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
Rleg_3653  phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I [KO:K01835] [EC:5.4.2.2]
Rleg_3026  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Rleg_1187  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Rleg_0578  phosphoribosylamine/glycine ligase [KO:K01945] [EC:6.3.4.13]
Rleg_1240  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Rleg_2144  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
Rleg_2136  phosphoribosylformylglycinamidine synthase, purS [KO:K23264] [EC:6.3.5.3]
Rleg_2138  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
Rleg_1241  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Rleg_3574  phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
Rleg_3573  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
Rleg_3443  Phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Rleg_2135  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Rleg_2128  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Rleg_4239  phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Rleg_3039  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Rleg_3605  5'-Nucleotidase domain protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Rleg_1689  stationary-phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Rleg_4463  purine nucleotide phosphorylase [KO:K03783] [EC:2.4.2.1]
Rleg_3023  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Rleg_3863  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Rleg_0477  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Rleg_1224  Nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Rleg_0004  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Rleg_1591  Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
Rleg_3133  xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
Rleg_3135  xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
Rleg_4658  aldehyde oxidase and xanthine dehydrogenase molybdopterin binding [KO:K11177] [EC:1.17.1.4]
Rleg_4659  molybdopterin dehydrogenase FAD-binding [KO:K11178] [EC:1.17.1.4]
Rleg_4660  (2Fe-2S)-binding domain protein [KO:K13483]
Rleg_4025  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Rleg_4571  GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
Rleg_3142  guanine deaminase [KO:K01487] [EC:3.5.4.3]
Rleg_1205  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Rleg_3793  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
Rleg_1589  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
Rleg_3792  Ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
Rleg_1679  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Rleg_1164  putative hydrolase protein [KO:K06952] [EC:3.1.3.89]
Rleg_1146  (p)ppGpp synthetase I, SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Rleg_1245  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Rleg_0472  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Rleg_0018  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_7122  putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_2702  adenylate/guanylate cyclase with Chase sensor [KO:K01768] [EC:4.6.1.1]
Rleg_3663  adenylate/guanylate cyclase with Chase sensor [KO:K01768] [EC:4.6.1.1]
Rleg_2024  adenylate/guanylate cyclase with Chase sensor [KO:K01768] [EC:4.6.1.1]
Rleg_1248  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_0956  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_0831  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_3642  adenylate/guanylate cyclase with TPR repeats [KO:K01768] [EC:4.6.1.1]
Rleg_3770  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_3791  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_7104  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_2375  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_2493  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_2399  conserved hypothetical protein [KO:K01768] [EC:4.6.1.1]
Rleg_2682  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_3418  adenylate/guanylate cyclase with TPR repeats [KO:K01768] [EC:4.6.1.1]
Rleg_6629  adenylate/guanylate cyclase with TPR repeats [KO:K01768] [EC:4.6.1.1]
Rleg_1960  adenylate/guanylate cyclase with TPR repeats [KO:K01768] [EC:4.6.1.1]
Rleg_2490  adenylate/guanylate cyclase with TPR repeats [KO:K01768] [EC:4.6.1.1]
Rleg_3419  adenylate/guanylate cyclase with TPR repeats [KO:K01768] [EC:4.6.1.1]
Rleg_2817  putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Rleg_3346  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Rleg_4468  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Rleg_1114  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Rleg_1650  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
Rleg_3101  adenine deaminase [KO:K01486] [EC:3.5.4.2]
Rleg_3451  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
Rleg_4006  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
Rleg_1605  5'-Nucleotidase domain protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Rleg_3506  metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
Rleg_1451  adenylate kinase [KO:K00939] [EC:2.7.4.3]
Rleg_1821  MazG family protein [KO:K04765] [EC:3.6.1.9]
Rleg_6761  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
Rleg_0880  sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
Rleg_0881  sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
Rleg_0669  FAD-dependent pyridine nucleotide-disulphide oxidoreductase [KO:K22879] [EC:1.14.13.113]
Rleg_3148  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
Rleg_2916  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
Rleg_4635  Allantoinase [KO:K01466] [EC:3.5.2.5]
Rleg_3152  urate catabolism protein [KO:K16842] [EC:3.5.2.5]
Rleg_6664  allantoin catabolism protein [KO:K14977] [EC:3.5.3.26]
Rleg_3149  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Rleg_3307  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Rleg_3310  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
Rleg_3312  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rlg00030  Pentose phosphate pathway
rlg00220  Arginine biosynthesis
rlg00250  Alanine, aspartate and glutamate metabolism
rlg00260  Glycine, serine and threonine metabolism
rlg00340  Histidine metabolism
rlg00630  Glyoxylate and dicarboxylate metabolism
rlg00730  Thiamine metabolism
rlg00740  Riboflavin metabolism
rlg00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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