KEGG   PATHWAY: sbi00350
Entry
sbi00350                    Pathway                                
Name
Tyrosine metabolism - Sorghum bicolor (sorghum)
Class
Metabolism; Amino acid metabolism
Pathway map
sbi00350  Tyrosine metabolism
sbi00350

Module
sbi_M00044  Tyrosine degradation, tyrosine => homogentisate [PATH:sbi00350]
Other DBs
GO: 0006570
Organism
Sorghum bicolor (sorghum) [GN:sbi]
Gene
110433801  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
110435098  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
110434826  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
8062394  bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase [KO:K15849] [EC:2.6.1.1 2.6.1.78 2.6.1.79]
8077154  bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase [KO:K15849] [EC:2.6.1.1 2.6.1.78 2.6.1.79]
8055490  nicotianamine aminotransferase A [KO:K00815] [EC:2.6.1.5]
8059342  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
8058608  nicotianamine aminotransferase A [KO:K00815] [EC:2.6.1.5]
110435496  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
110435653  probable aminotransferase TAT2 isoform X1 [KO:K00815] [EC:2.6.1.5]
8078226  tyrosine aminotransferase isoform X1 [KO:K00815] [EC:2.6.1.5]
8073847  histidinol-phosphate aminotransferase, chloroplastic [KO:K00817] [EC:2.6.1.9]
8084603  4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
8077168  4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
8066857  homogentisate 1,2-dioxygenase [KO:K00451] [EC:1.13.11.5]
8068911  glutathione S-transferase Z1 [KO:K01800] [EC:5.2.1.2]
8058134  glutathione S-transferase [KO:K01800] [EC:5.2.1.2]
110429774  glutathione S-transferase [KO:K01800] [EC:5.2.1.2]
8076918  glutathione S-transferase zeta class [KO:K01800] [EC:5.2.1.2]
110434603  fumarylacetoacetase [KO:K01555] [EC:3.7.1.2]
8054733  polyphenol oxidase, chloroplastic [KO:K00422] [EC:1.10.3.1]
8056609  polyphenol oxidase I, chloroplastic [KO:K00422] [EC:1.10.3.1]
8071138  polyphenol oxidase I, chloroplastic [KO:K00422] [EC:1.10.3.1]
8071139  polyphenol oxidase II, chloroplastic [KO:K00422] [EC:1.10.3.1]
8067652  polyphenol oxidase, chloroplastic [KO:K00422] [EC:1.10.3.1]
8071140  polyphenol oxidase I, chloroplastic [KO:K00422] [EC:1.10.3.1]
8057594  polyphenol oxidase I, chloroplastic [KO:K00422] [EC:1.10.3.1]
8079268  polyphenol oxidase I, chloroplastic [KO:K00422] [EC:1.10.3.1]
8067813  aromatic-L-amino-acid decarboxylase [KO:K01593] [EC:4.1.1.28 4.1.1.105]
8067546  tyrosine decarboxylase 1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
8067812  aromatic-L-amino-acid decarboxylase [KO:K01593] [EC:4.1.1.28 4.1.1.105]
8057946  tyrosine decarboxylase 1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
8072418  tyrosine decarboxylase 1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
8072417  tyrosine decarboxylase 1 [KO:K01593] [EC:4.1.1.28 4.1.1.105]
8073581  uncharacterized protein LOC8073581 [KO:K00276] [EC:1.4.3.21]
8063333  uncharacterized protein LOC8063333 [KO:K00276] [EC:1.4.3.21]
8081828  primary amine oxidase 2 [KO:K00276] [EC:1.4.3.21]
8068603  primary amine oxidase 2 [KO:K00276] [EC:1.4.3.21]
8056374  primary amine oxidase 2 [KO:K00276] [EC:1.4.3.21]
8069427  primary amine oxidase [KO:K00276] [EC:1.4.3.21]
8056438  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
110432921  alcohol dehydrogenase-like 2 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
110432922  alcohol dehydrogenase-like 2 isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
8081917  alcohol dehydrogenase-like 7 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
8057637  alcohol dehydrogenase-like 7 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
8064371  alcohol dehydrogenase 2 [KO:K18857] [EC:1.1.1.1]
8064373  alcohol dehydrogenase 1 [KO:K18857] [EC:1.1.1.1]
110436814  alcohol dehydrogenase 1 isoform X1 [KO:K18857] [EC:1.1.1.1]
8061367  alcohol dehydrogenase-like 4 isoform X1 [KO:K00001] [EC:1.1.1.1]
8074802  alcohol dehydrogenase-like 6 [KO:K00001] [EC:1.1.1.1]
8083829  alcohol dehydrogenase-like 4 isoform X2 [KO:K00001] [EC:1.1.1.1]
8054147  acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
8079678  acylpyruvase FAHD1, mitochondrial [KO:K01557] [EC:3.7.1.5]
8055497  macrophage migration inhibitory factor homolog isoform X2 [KO:K07253] [EC:5.3.2.1]
8063823  macrophage migration inhibitory factor homolog isoform X2 [KO:K07253] [EC:5.3.2.1]
8079974  macrophage migration inhibitory factor homolog [KO:K07253] [EC:5.3.2.1]
Compound
C00022  Pyruvate
C00042  Succinate
C00082  L-Tyrosine
C00122  Fumarate
C00146  Phenol
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00355  3,4-Dihydroxy-L-phenylalanine
C00483  Tyramine
C00530  Hydroquinone
C00544  Homogentisate
C00547  L-Noradrenaline
C00628  2,5-Dihydroxybenzoate
C00642  4-Hydroxyphenylacetate
C00788  L-Adrenaline
C00811  4-Coumarate
C00822  Dopaquinone
C01036  4-Maleylacetoacetate
C01060  3,5-Diiodo-L-tyrosine
C01061  4-Fumarylacetoacetate
C01161  3,4-Dihydroxyphenylacetate
C01179  3-(4-Hydroxyphenyl)pyruvate
C01384  Maleic acid
C01693  L-Dopachrome
C01829  Thyroxine
C01850  Rosmarinate
C02167  Maleylpyruvate
C02442  N-Methyltyramine
C02465  Triiodothyronine
C02514  3-Fumarylpyruvate
C02515  3-Iodo-L-tyrosine
C03063  2-Oxohept-3-enedioate
C03077  4-Chlorophenylacetate
C03758  Dopamine
C03765  4-Hydroxyphenylacetaldehyde
C03964  (R)-3-(4-Hydroxyphenyl)lactate
C04043  3,4-Dihydroxyphenylacetaldehyde
C04045  3-(3,4-Dihydroxyphenyl)pyruvate
C04052  5-Carboxy-2-oxohept-3-enedioate
C04185  5,6-Dihydroxyindole-2-carboxylate
C04186  5-Carboxymethyl-2-hydroxymuconate
C04368  3-Amino-3-(4-hydroxyphenyl)propanoate
C04642  2-Hydroxy-5-carboxymethylmuconate semialdehyde
C04796  4-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C04797  5-(L-Alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde
C05338  4-Hydroxyphenylacetyl-CoA
C05350  2-Hydroxy-3-(4-hydroxyphenyl)propenoate
C05576  3,4-Dihydroxyphenylethyleneglycol
C05577  3,4-Dihydroxymandelaldehyde
C05578  5,6-Dihydroxyindole
C05579  Indole-5,6-quinone
C05580  3,4-Dihydroxymandelate
C05581  3-Methoxy-4-hydroxyphenylacetaldehyde
C05582  Homovanillate
C05583  3-Methoxy-4-hydroxyphenylglycolaldehyde
C05584  3-Methoxy-4-hydroxymandelate
C05585  Gentisate aldehyde
C05587  3-Methoxytyramine
C05588  L-Metanephrine
C05589  L-Normetanephrine
C05593  3-Hydroxyphenylacetate
C05594  3-Methoxy-4-hydroxyphenylethyleneglycol
C05595  4-Hydroxyphenylacetylglutamic acid
C05596  p-Hydroxyphenylacetylglycine
C05600  2-Hydroxyhepta-2,4-dienedioate
C05604  2-Carboxy-2,3-dihydro-5,6-dihydroxyindole
C06044  4-Hydroxyphenylethanol
C06046  Salidroside
C06047  Stizolobate
C06048  Stizolobinate
C06199  Hordenine
C06201  2,4-Dihydroxyhept-2-enedioate
C10447  3,4-Dihydroxyphenylpropanoate
C17935  Cysteinyldopa
C17936  Phaeomelanin
C17937  Eumelanin
C17938  5,6-Indolequinone-2-carboxylic acid
C22038  (R)-3-(3,4-Dihydroxyphenyl)lactate
Reference
PMID:8550403
  Authors
Prieto MA, Diaz E, Garcia JL.
  Title
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
  Journal
J Bacteriol 178:111-20 (1996)
DOI:10.1128/JB.178.1.111-120.1996
Reference
PMID:1194238
  Authors
Sparnins VL, Dagley S.
  Title
Alternative routes of aromatic catabolism in Pseudomonas acidovorans and Pseudomonas putida: gallic acid as a substrate and inhibitor of dioxygenases.
  Journal
J Bacteriol 124:1374-81 (1975)
DOI:10.1128/JB.124.3.1374-1381.1975
Reference
PMID:18435614
  Authors
Ito S, Wakamatsu K
  Title
Chemistry of mixed melanogenesis--pivotal roles of dopaquinone.
  Journal
Photochem Photobiol 84:582-92 (2008)
DOI:10.1111/j.1751-1097.2007.00238.x
Reference
PMID:11171088
  Authors
Olivares C, Jimenez-Cervantes C, Lozano JA, Solano F, Garcia-Borron JC
  Title
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.
  Journal
Biochem J 354:131-9 (2001)
DOI:10.1042/bj3540131
Related
pathway
sbi00020  Citrate cycle (TCA cycle)
sbi00360  Phenylalanine metabolism
sbi00400  Phenylalanine, tyrosine and tryptophan biosynthesis
sbi00620  Pyruvate metabolism
sbi00650  Butanoate metabolism
sbi00940  Phenylpropanoid biosynthesis
sbi00950  Isoquinoline alkaloid biosynthesis
KO pathway
ko00350   
LinkDB

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