KEGG   PATHWAY: sfj00230
Entry
sfj00230                    Pathway                                
Name
Purine metabolism - Serratia ficaria
Class
Metabolism; Nucleotide metabolism
Pathway map
sfj00230  Purine metabolism
sfj00230

Module
sfj_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sfj00230]
sfj_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sfj00230]
sfj_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sfj00230]
sfj_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sfj00230]
sfj_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sfj00230]
sfj_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sfj00230]
sfj_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:sfj00230]
Other DBs
GO: 0006163 0042278
Organism
Serratia ficaria [GN:sfj]
Gene
SAMEA4384070_4238  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SAMEA4384070_4571  nudE; ADP compounds hydrolase nudE [KO:K08312] [EC:3.6.1.-]
SAMEA4384070_0691  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SAMEA4384070_1293  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
SAMEA4384070_2057  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SAMEA4384070_3453  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
SAMEA4384070_0282  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
SAMEA4384070_3654  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SAMEA4384070_2850  purT; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
SAMEA4384070_3766  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
SAMEA4384070_3653  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
SAMEA4384070_1191  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
SAMEA4384070_1192  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
SAMEA4384070_3631  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
SAMEA4384070_2096  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SAMEA4384070_0283  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SAMEA4384070_1161  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SAMEA4384070_1174  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
SAMEA4384070_0857  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
SAMEA4384070_1279  nagD; UMP phosphatase [KO:K02566] [EC:3.1.3.5]
SAMEA4384070_4573  (S)-2-haloacid dehalogenase [KO:K20881] [EC:3.1.3.-]
SAMEA4384070_1171  gsk; Inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
SAMEA4384070_0692  deoD; Purine nucleoside phosphorylase deoD-type [KO:K03784] [EC:2.4.2.1]
SAMEA4384070_1061  Uncharacterized protein conserved in bacteria [KO:K09913] [EC:2.4.2.1 2.4.2.2]
SAMEA4384070_0909  yfiH_1; Laccase domain protein yfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SAMEA4384070_4366  rihB; Pyrimidine-specific ribonucleoside hydrolase rihB [KO:K25589] [EC:3.2.2.2 3.2.2.3]
SAMEA4384070_4118  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SAMEA4384070_3714  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SAMEA4384070_3731  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SAMEA4384070_0705  yjjX; Non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
SAMEA4384070_4151  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
SAMEA4384070_0994  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
SAMEA4384070_2372  hcrC_1; 4-hydroxybenzoyl-CoA reductase subunit gamma [KO:K13481] [EC:1.17.1.4]
SAMEA4384070_2373  hcrA; 4-hydroxybenzoyl-CoA reductase subunit alpha [KO:K13482] [EC:1.17.1.4]
SAMEA4384070_2610  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
SAMEA4384070_3713  guaA_1; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
SAMEA4384070_4280  guaA_2; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
SAMEA4384070_0799  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
SAMEA4384070_2371  guaD; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
SAMEA4384070_4785  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
SAMEA4384070_3387  nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
SAMEA4384070_3836  nrdE; Ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
SAMEA4384070_3388  nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta [KO:K00526] [EC:1.17.4.1]
SAMEA4384070_3837  nrdF; Ribonucleoside-diphosphate reductase 2 subunit beta [KO:K00526] [EC:1.17.4.1]
SAMEA4384070_0552  nrdD; Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SAMEA4384070_0812  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
SAMEA4384070_3427  yfbR; 5'-nucleotidase yfbR [KO:K08722] [EC:3.1.3.89]
SAMEA4384070_4787  spoT_2; Bifunctional (p)ppGpp synthase/hydrolase SpoT [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SAMEA4384070_0122  gppA; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SAMEA4384070_3662  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SAMEA4384070_0824  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
SAMEA4384070_0148  adenylate cyclase [KO:K05851] [EC:4.6.1.1]
SAMEA4384070_1303  Low-affinity cAMP phosphodiesterase [KO:K01120] [EC:3.1.4.17]
SAMEA4384070_0456  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SAMEA4384070_2320  Adenine deaminase [KO:K01488] [EC:3.5.4.4]
SAMEA4384070_3190  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
SAMEA4384070_3919  ygdH; LOG family protein ygdH [KO:K06966] [EC:3.2.2.10 3.2.2.-]
SAMEA4384070_1142  ade2; Adenine deaminase 2 [KO:K01486] [EC:3.5.4.2]
SAMEA4384070_0472  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SAMEA4384070_1321  yfkN; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SAMEA4384070_1166  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
SAMEA4384070_0825  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
SAMEA4384070_4235  cpdA_1; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
SAMEA4384070_4236  cpdA_2; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
SAMEA4384070_0744  apaH; Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
SAMEA4384070_0848  cysC; Adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
SAMEA4384070_0847  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
SAMEA4384070_0846  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
SAMEA4384070_2390  xlnD; 3-hydroxybenzoate 6-hydroxylase 1 [KO:K16839] [EC:1.14.13.113]
SAMEA4384070_0969  hiuH; 5-hydroxyisourate hydrolase precursor [KO:K07127] [EC:3.5.2.17]
SAMEA4384070_0968  uao; Uric acid degradation bifunctional protein [KO:K16840] [EC:4.1.1.97]
SAMEA4384070_0948  Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
SAMEA4384070_0949  putative urate catabolism protein [KO:K16842] [EC:3.5.2.5]
SAMEA4384070_0967  hyuC; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
SAMEA4384070_0966  pucG; Purine catabolism protein PucG [KO:K00839] [EC:2.6.1.112]
SAMEA4384070_0958  gatA_1; Glutamyl-tRNA(Gln) amidotransferase subunit A [KO:K22601] [EC:2.1.3.5]
SAMEA4384070_0960  ywrD; Putative gamma-glutamyltransferase ywrD [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sfj00030  Pentose phosphate pathway
sfj00220  Arginine biosynthesis
sfj00250  Alanine, aspartate and glutamate metabolism
sfj00260  Glycine, serine and threonine metabolism
sfj00340  Histidine metabolism
sfj00630  Glyoxylate and dicarboxylate metabolism
sfj00730  Thiamine metabolism
sfj00740  Riboflavin metabolism
sfj00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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