PATHWAY: sme02010 Help
Entry
Name
ABC transporters - Sinorhizobium meliloti 1021
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
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Organism
Sinorhizobium meliloti 1021 [GN:
sme ]
Gene
SMa2069 cysP1; ABC-type sulfate transport system, periplasmic component [KO:K02048 ]
SM_b21131 cysP2; ABC-type sulfate transport system, periplasmic component [KO:K02047 ]
SMa0585 nrtA; Nitrate transporter, periplasmic nitrate binding protein [KO:K15576 ]
SM_b21526 tauA; ABC transporter, periplasmic solute-binding protein [KO:K15551 ]
SM_b21528 tauC; putative taurine uptake ABC transporter permease protein [KO:K15552 ]
SMc03196 modA; Putative molybdate-binding periplasmic ABC transporter [KO:K02020 ]
SMc03197 modB; Putative molybdenum transport system permease ABC transporter [KO:K02018 ]
SM_b21540 putative iron uptake ABC transporter periplasmic solute-binding protein precursor [KO:K02012 ]
SM_b20158 hypothetical ABC transporter periplasmic solute-binding protein [KO:K02012 ]
SM_b20157 hypothetical ABC transporter periplasmic solute-binding protein [KO:K02012 ]
SMa0522 ABC transporter, periplasmic solute-binding protein [KO:K02012 ]
SM_b20723 putative iron ABC transporter periplasmic solute-binding protein precursor [KO:K02012 ]
SMc00775 fbpB; ABC-type Fe3+ transport system, permease component [KO:K02011 ]
SM_b21542 putative iron uptake ABC transporter permease protein [KO:K02011 ]
SMc03869 thiB; Thiamine-binding periplasmic protein precursor [KO:K02064 ]
SM_b20284 putative ABC transporter periplasmic spermidineputrescine-binding protein [KO:K11069 ]
SM_b20282 probable spermidineputrescine ABC transporter permease protein [KO:K11070 ]
SM_b20283 probable spermidineputrescine ABC transporter permease protein [KO:K11071 ]
SMc00770 potF; Probable putrescine-binding periplasmic protein [KO:K11073 ]
SMc00773 potI; Probable putrescine transport system permease [KO:K11074 ]
SMc00772 potH; Probable putrescine transport system permease [KO:K11075 ]
SMa0950 ABC transporter, periplasmic solute-binding protein [KO:K11077 ]
SMc00672 hisX; Histidine ABC transporter, periplasmic solute-binding protein [KO:K02002 ]
SMc02737 choX; Putative choline ABC transporter, periplasmic solute-binding component [KO:K02002 ]
SM_b21572 putative amino acid uptake ABC transporter periplasmic solute-binding protein precursor [KO:K02002 ]
SMa1729 proX; ABC transporter, periplasmic solute-binding protein [KO:K02002 ]
SMc02378 Probable glycine betaine ABC transporter, periplasmic substrate-binding component [KO:K02002 ]
SMc02738 choW; Putative choline ABC transporter, permease component [KO:K02001 ]
SMc02379 Probable glycine betaine ABC transporter, permease [KO:K02001 ]
SM_b21144 putative choline uptake ABC transporter periplasmic solute-binding protein precursor [KO:K05845 ]
SMa1462 ABC transporter, periplasmic solute-binding protein [KO:K05845 ]
SM_b21145 putative choline uptake ABC transporter permease protein [KO:K05846 ]
SM_b21147 putative choline uptake ABC transporter permease protein [KO:K05846 ]
SMc01499 smoK; Putative C6 polyol ABC transporter, ATP-binding component [KO:K10111 ] [EC:7.5.2.-]
SMc04140 Putative amino acid or peptide ABC transporter, ATP-binding component [KO:K10111 ] [EC:7.5.2.-]
SMa2311 ABC transporter, ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
SM_b21460 putative sugar uptake ABC transporter ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
SMc02869 Putative ATP-binding ABC transporter [KO:K10111 ] [EC:7.5.2.-]
SM_b20328 thuK; ThuK ABC transporter, ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
SM_b20630 putative sugar uptake ABC transporter ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
SM_b21605 putative sugar uptake ABC transporter ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
SMc04256 Putative gentiobiose, salicin, and cellobiose ABC transporter, ATP-binding component [KO:K10112 ] [EC:7.5.2.-]
SMc04393 Putative dextrin ABC sugar transporter, ATP-binding component [KO:K10112 ] [EC:7.5.2.-]
SM_b21106 putative sugar uptake ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
SMc01625 Putative polyol ABC transporter, ATP-binding component [KO:K10112 ] [EC:7.5.2.-]
SMc01624 Putative polyol ABC transporter, ATP-binding component [KO:K10112 ] [EC:7.5.2.-]
SMa0714 ABC transporter, ATP-binding protein, carboxyl terminus [KO:K10112 ] [EC:7.5.2.-]
SM_b20661 putative sugar uptake ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
SM_b20235 putative sugar ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
SMc02474 Putative ATP-binding ABC transporter [KO:K10112 ] [EC:7.5.2.-]
SMa1345 ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
SM_b21592 putative sugar uptake ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
SMa1344 ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
SMa0713 ABC transporter, ATP-binding protein, amino terminus [KO:K10112 ] [EC:7.5.2.-]
SMc02472 Putative transport system permease ABC transporter [KO:K10118 ]
SMc02473 Putative transport system permease ABC transporter [KO:K10119 ]
SM_b21652 lacE; ABC transporter, periplasmic solute-binding protein [KO:K10188 ]
SMc01496 smoE; Putative C6 polyol ABC transporter, periplasmic solute-binding component [KO:K10227 ]
SMc01497 smoF; Putative C6 polyol ABC transporter, permease component [KO:K10228 ]
SMc01498 smoG; Putative C6 polyol ABC transporter, permease component [KO:K10229 ]
SMc03061 aglE; Alpha-glucosides ABC transporter, periplasmic substrate-binding component [KO:K10232 ]
SMc03062 aglF; Alpha-glucosides ABC transporter, permease component [KO:K10233 ]
SMc03063 aglG; Alpha-glucosides ABC transporter, permease component [KO:K10234 ]
SMc03065 aglK; Alpha-glucosides ABC transporter, ATP binding component [KO:K10235 ]
SM_b20325 thuE_OR_Smb20325; ThuE, ABC transporter, periplasmic solute-binding protein [KO:K10236 ]
SM_b21461 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor [KO:K10236 ]
SM_b21459 putative sugar uptake ABC transporter permease protein [KO:K10237 ]
SM_b21458 putative sugar uptake ABC transporter permease protein [KO:K10238 ]
SM_b20895 araA; ABC transporter, periplasmic solute-binding protein [KO:K10546 ]
SM_b20894 araB; ABC transporter, ATP-binding protein [KO:K10548 ] [EC:7.5.2.-]
SMc00243 Putative transport system permease ABC transporter [KO:K23535 ]
SMc00244 Putative transport system permease ABC transporter [KO:K23536 ]
SMc04259 Putative gentiobiose, salicin, and cellobiose ABC transporter, periplasmic solute-binding component [KO:K17315 ]
SMc04396 Putative dextrin ABC transporter, periplasmic solute-binding component [KO:K17315 ]
SMc04258 Putative gentiobiose, salicin, and cellobiose ABC transporter, permease component [KO:K17316 ]
SMc04395 Putative dextrin ABC sugar transporter, permease component [KO:K17316 ]
SMc04257 Putative gentiobiose, salicin, and cellobiose ABC transporter, permease component [KO:K17317 ]
SMc04394 Putative dextrin ABC sugar transporter, permease component [KO:K17317 ]
SM_b20720 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor [KO:K10439 ]
SMc02774 Putative D-fucose, pyruvic acid or L-fucose ABC transporter, periplasmic substrate-binding component [KO:K10439 ]
SM_b20504 putative ABC transporter periplasmic sugar-binding protein [KO:K10439 ]
SMa0203 ABC transporter, periplasmic solute-binding protein [KO:K10439 ]
SMa1427 ABC transporter, periplasmic solute-binding protein [KO:K10439 ]
SMc02021 Putative organic acid ABC transporter, periplasmic solute-binding component [KO:K10439 ]
SMa2000 ABC transporter, periplasmic solute-binding protein [KO:K10439 ]
SM_b20671 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor [KO:K10439 ]
SMa0273 ABC transporter, periplasmic solute-binding protein [KO:K10439 ]
SMc02772 Putative D-fucose, pyruvic acid or L-fucose ABC transporter, permease component [KO:K10440 ]
SMc02019 Putative organic acid ABC transporter, permease component [KO:K10440 ]
SMc02773 Putative D-fucose, pyruvic acid or L-fucose ABC transporter, ATP-binding component [KO:K10441 ] [EC:7.5.2.7 ]
SM_b21587 Sugar ABC transporter, periplasmic solute-binding protein [KO:K23508 ]
SMc02171 frcB; Putative fructose ABC-type transport system, periplasmic component [KO:K10552 ]
SMc02170 frcC; Putative fructose ABC-type transport system, permease component [KO:K10553 ]
SMc02169 frcA; Putative fructose ABC-type transport system, ATPase component [KO:K10554 ]
SMc02324 rhaS; ABC transporter, periplasmic rhamnose binding protein [KO:K10559 ]
SMc02325 rhaT; ATP-binding component of rhamnose transport system [KO:K10562 ] [EC:7.5.2.-]
SMc02514 Putative glycerol-3-phosphate and glycerol ABC transporter, periplasmic solute-binding component [KO:K17321 ]
SMc02517 Putative glycerol-3-phosphate and glycerol ABC transporter, permease component [KO:K17322 ]
SMc02516 Putative glycerol-3-phosphate and glycerol ABC transporter, permease component [KO:K17323 ]
SMc02519 Putative glycerol-3-phosphate and glycerol ABC transporter, ATP-binding component [KO:K17324 ]
SMc02518 Putative glycerol-3-phosphate and glycerol ABC transporter, ATP-binding component [KO:K17325 ]
SM_b20416 ugpB; probable ABC transporter periplasmic glycerol-3-phosphate-binding protein precursor [KO:K05813 ]
SM_b20417 ugpA; probable glycerol-3-phosphate ABC transporter permease protein [KO:K05814 ]
SM_b20418 ugpE; probable glycerol-3-phosphate ABC transporter permease protein [KO:K05815 ]
SMc02143 pstA; Putative phosphate transport system permease ABC transporter [KO:K02038 ]
SM_b21176 phoD; phosphate uptake ABC transporter periplasmic solute-binding protein precursor [KO:K02044 ]
SM_b21175 phoE; phosphate uptake ABC transporter permease protein [KO:K02042 ]
SM_b21174 phoT; phosphate uptake ABC transporter permease protein [KO:K02042 ]
SMc02118 aapJ; Probable general L-amino acid-binding periplasmic ABC transporter [KO:K09969 ]
SMc00676 Putative amino acid-binding periplasmic signal peptide protein [KO:K09969 ]
SMc02119 aapQ; Probable general L-amino acid transport permease ABC transporter [KO:K09970 ]
SMc02120 aapM; Probable general L-amino acid transport permease ABC transporter [KO:K09971 ]
SMc02121 aapP; Probable general L-amino acid transport ATP-binding ABC transporter [KO:K09972 ] [EC:7.4.2.1 ]
SMc03891 Putative amino acid-binding periplasmic ABC transporter [KO:K02424 ]
SMc03893 Putative amino-acid transport system permease ABC transporter [KO:K10009 ]
SMa0495 ABC transporter, periplasmic solute-binding protein [KO:K10022 ]
SM_b20263 putative ABC transporter periplasmic amino acid-binding protein [KO:K23061 ]
SMc01946 livK; Putative leucine-specific binding protein precursor [KO:K01999 ]
SMc03121 Putative methionine ABC transporter, periplasmic solute-binding component [KO:K01999 ]
SMc00078 Putative methionine ABC transporter, periplasmic solute-binding protein [KO:K01999 ]
SMc02356 Putative branched chain amino acid binding periplasmic ABC transporter [KO:K01999 ]
SMa0576 ABC transporter, periplasmic solute-binding protein [KO:K01999 ]
SMc00598 Putative branched-chain amino acid transport permease [KO:K01997 ]
SMc03118 Putative methionine ABC transporter, permease component [KO:K01997 ]
SMc01951 livH; Probable high-affinity branched-chain amino acid transport permease ABC transporter [KO:K01997 ]
SMc02359 Putative high-affinity branched-chain amino acid transport permease ABC transporter [KO:K01997 ]
SMc03117 Putative methionine ABC transporter, permease component [KO:K01998 ]
SMc01950 livM; ABC-type branched-chain amino acid transport system, permease component [KO:K01998 ]
SMc02360 Putative branched chain amino acid transport system permease ABC transporter [KO:K01998 ]
SMc03120 Putative methionine ABC transporter, ATP-binding component [KO:K01995 ]
SMc01949 livG; Probable high-affinity branched-chain amino acid transport ATP-binding ABC transporter [KO:K01995 ]
SMc02357 Putative high-affinity branched-chain amino acid transport ATP-binding ABC transporter [KO:K01995 ]
SMc02358 Putative high-affinity branched-chain amino acid transport ATP-binding ABC transporter [KO:K01996 ]
SMc03119 Putative methionine ABC transporter, ATP-binding component [KO:K01996 ]
SMc01948 livF; Probable high-affinity branched-chain amino acid transport ATP-binding ABC transporter [KO:K01996 ]
SM_b20784 putative branched-chain amino acid uptake ABC transporter ATP-binding protein [KO:K01996 ]
SMc03157 metQ; Probable D-methionine-binding lipoprotein MetQ [KO:K02073 ]
SMc03158 metI; Probable D-methionine transport system permease protein MetI [KO:K02072 ]
SMc00786 dppA1; Putative amino acid or peptide ABC transporter, periplasmic solute-binding component [KO:K12368 ]
SMc00787 dppB1; Putative amino acid or peptide ABC transporter, permease component [KO:K12369 ]
SMc00788 dppC1; Putative amino acid or peptide ABC transporter, permease component [KO:K12370 ]
SMc00789 dppD1; Putative amino acid or peptide ABC transporter, ATP-binding component [KO:K12371 ]
SMc00790 dppF1; Putative amino acid or peptide ABC transporter, ATP-binding component [KO:K12372 ]
SMc02832 Putative taurine, valine, isoleucine and leucine ABC transporter, periplasmic solute-binding component [KO:K13893 ]
SMc02831 Putative taurine, valine, isoleucine and leucine ABC transporter, permease component [KO:K13894 ]
SMc02830 Putative taurine, valine, isoleucine and leucine ABC transporter, permease component [KO:K13895 ]
SMc02829 Putative taurine, valine, isoleucine and leucine ABC transporter, ATP-binding component [KO:K13896 ]
SMa1746 ABC transporter, periplasmic solute-binding protein [KO:K25286 ]
SMa1745 ABC transporter, permease, Fe3+-siderophore transport system [KO:K23186 ]
SMa1742 ABC transporter, permease, Fe3+-siderophore transport system [KO:K23187 ]
SMc04245 znuA; Probable high-affinity zinc uptake system ABC transporter [KO:K09815 ]
SMc04243 znuB; Probable high-affinity zinc uptake system membrane ABC transporter [KO:K09816 ]
SMc04244 znuC; Probable high-affinity zinc uptake system ATP-binding ABC transporter [KO:K09817 ] [EC:7.2.2.20 ]
SMc02509 sitA; Manganese ABC transporter periplasmic substrate binding protein [KO:K11604 ]
SMc00962 bioM; Biotin ABC transporter, ATP-binding component [KO:K16784 ] [EC:7.6.2.-]
SM_b20822 rkpT2; putative cell surface polysaccharide export ABC-2 transporter permease protein, close relative to wzm1Y20833 [KO:K09688 ]
SMa0864 nodI; NodI ABC transporter, ATP-binding protein [KO:K09695 ]
SMc01376 ABC transport system ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
SMc03850 ccmD; Putative heme exporter D (cytochrome C-type biogenesis protein) transmembrane [KO:K02196 ]
SMc03849 ccmC; Putative heme exporter C (cytochrome C-type biogenesis protein) transmembrane [KO:K02195 ]
SMc03848 ccmB; Putative heme exporter B (cytochrome C-type biogenesis protein) transmembrane [KO:K02194 ]
SMc03847 ccmA; Putative heme exporter A (cytochrome C-type biogenesis ATP-binding protein) ABC transporter [KO:K02193 ] [EC:7.6.2.5 ]
SMc02661 Putative toxin secretion ATP-binding ABC transporter [KO:K11004 ]
SMc00550 Probable ABC transporter ATP-binding transmembrane protein [KO:K24821 ]
SMc00186 Putative ABC transporter ATP-binding transmembrane protein [KO:K18893 ]
SMc00185 Putative ABC transporter ATP-binding transmembrane transmembrane protein [KO:K18893 ]
SM_b21316 wgdA; ABC-type multidrug transport system protein WgdA (formerly ExpD1) [KO:K12536 ]
SMc04351 macB; Probable macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
SM_b20937 exsE; putative ABC transporter protein consisting of fused ATP-binding and permease components [KO:K02471 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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