Entry
Name
ABC transporters - Salmonella enterica subsp. enterica serovar Paratyphi A ATCC9150
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Salmonella enterica subsp. enterica serovar Paratyphi A ATCC9150 [GN:
spt ]
Gene
SPA0423 cysU; sulphate transport system permease protein CysT [KO:K02046 ]
SPA0424 cysW; sulphate transport system permease protein CysW [KO:K02047 ]
SPA1971 modA; molybdate-binding periplasmic protein precursor [KO:K02020 ]
SPA1970 modB; molybdenum transport system permease protein ModB [KO:K02018 ]
SPA1974 modF; putative molybdenum transport ATP-binding protein ModF (photorepair protein PhrA) [KO:K05776 ]
SPA0110 tbpA; thiamine-binding periplasmic protein precursor [KO:K02064 ]
SPA0109 yabK; putative ABC transporter integral membrane protein [KO:K02063 ]
SPA1628 potD; spermidine/putrescine-binding periplasmic protein precursor [KO:K11069 ]
SPA1627 potC; spermidine/putrescine transport system permease protein PotC [KO:K11070 ]
SPA1625 potB; spermidine/putrescine transport system permease protein PotB [KO:K11071 ]
SPA1624 potA; spermidine/putrescine transport ATP-binding protein PotA (ABC superfamily) [KO:K11072 ] [EC:7.6.2.11 ]
SPA1885 potF; putrescine-binding periplasmic protein precursor [KO:K11073 ]
SPA1882 potI; putrescine transport system permease protein PotI [KO:K11074 ]
SPA1883 potH; putrescine transport system permease protein PotH [KO:K11075 ]
SPA2294 phnS; probable periplasmic binding component of 2-aminoethylphosphonate transporter [KO:K11081 ]
SPA2297 phnV; probable membrane component of 2-aminoethylphosphonate transporter [KO:K11082 ]
SPA2296 phnU; probable membrane component of 2-aminoethylphosphonate transporter [KO:K11083 ]
SPA2295 phnT; probable ATP-binding component of 2-aminoethylphosphonate transporter [KO:K11084 ]
SPA2669 proX; glycine betaine-binding periplasmic protein precursor [KO:K02002 ]
SPA2668 proW; glycine betaine/L-proline transport system permease protein P [KO:K02001 ]
SPA2667 proV; ABC superfamily (atp_bind), glycine/betaine/proline transport protein [KO:K02000 ] [EC:7.6.2.9 ]
SPA1361 putative ABC transporter periplasmic binding protein [KO:K05845 ]
SPA0687 yehY; putative permease transmembrane component [KO:K05846 ]
SPA0689 yehW; putative permease transmembrane component [KO:K05846 ]
SPA4045 malF; maltose transport inner membrane protein [KO:K10109 ]
SPA4044 malG; maltose transport inner membrane protein [KO:K10110 ]
SPA4047 malK; maltose/maltodextrin transport ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
SPA3180 yrbF; possible ABC-transport protein, ATP-binding component [KO:K02065 ]
SPA0661 mglB; D-galactose-binding periplasmic protein precursor [KO:K10540 ]
SPA0663 mglC; galactoside transport system permease protein MglC [KO:K10541 ]
SPA3409 ugpB; glycerol-3-phosphate-binding periplasmic protein [KO:K05813 ]
SPA3408 ugpA; glycerol-3-phosphate transport system permease protein [KO:K05814 ]
SPA3407 ugpE; sn-Glycerol-3-phosphate transport system permease protein [KO:K05815 ]
SPA3697 pstC; phosphate transport system permease protein [KO:K02037 ]
SPA3696 pstA; phosphate transport system permease protein [KO:K02038 ]
SPA0509 argT; lysine-arginine-ornithine-binding periplasmic protein precursor [KO:K10013 ]
SPA0511 hisQ; histidine transport system permease protein [KO:K10016 ]
SPA1923 glnH; glutamine-binding periplasmic protein precursor [KO:K10036 ]
SPA1924 glnP; glutamine transport system permease protein GlnP [KO:K10037 ]
SPA1872 artI; arginine-binding periplasmic protein 1 precursor [KO:K09997 ]
SPA1874 artM; arginine transport system permease protein ArtM [KO:K09998 ]
SPA1873 artQ; arginine transport system permease protein ArtQ [KO:K09999 ]
SPA2075 ybeJ; ABC transporter periplasmic binding protein [KO:K10001 ]
SPA2077 gltK; glutamate/aspartate transport system permease protein GltK [KO:K10002 ]
SPA2076 gltJ; glutamate/aspartate transport system permease protein GltJ [KO:K10003 ]
SPA0915 fliY; cystine-binding periplasmic protein precursor [KO:K02424 ]
SPA0917 yecS; putative ABC transporter membrane protein [KO:K10009 ]
SPA3418 livJ; ABC superfamily (bind_prot), branched-chain amino acid transporter, high-affinity [KO:K01999 ]
SPA3414 livH; high-affinity branched-chain amino acid transport system permease protein [KO:K01997 ]
SPA3413 livM; high-affinity branched-chain amino acid transport system permease protein [KO:K01998 ]
SPA3412 livG; high-affinity branched-chain amino acid transport ATP-binding protein [KO:K01995 ]
SPA3411 livF; high-affinity branched-chain amino acid transport ATP-binding protein [KO:K01996 ]
SPA0253 yaeE; putative ABC transporter permease protein [KO:K02072 ]
SPA2210 sfbC; ABC transporter integral membrane protein [KO:K02072 ]
SPA0254 abc; putative ABC transporter ATP-binding protein [KO:K02071 ]
SPA1131 oppA; periplasmic oligopeptide-binding protein precursor [KO:K15580 ]
SPA1205 mppA; periplasmic murein peptide-binding protein MppA [KO:K15580 ]
SPA1132 oppB; oligopeptide transport system permease protein OppB [KO:K15581 ]
SPA1133 oppC; ABC superfamily (membrane), oligopeptide transport protein [KO:K15582 ]
SPA1134 oppD; oligopeptide transport ATP-binding protein OppD [KO:K15583 ]
SPA1135 oppF; oligopeptide transport ATP-binding protein OppF [KO:K10823 ]
SPA3487 dppA; periplasmic dipeptide transport protein precursor [KO:K12368 ]
SPA3486 dppB; dipeptide transport system permease protein DppB [KO:K12369 ]
SPA3485 dppC; dipeptide transport system permease protein DppC [KO:K12370 ]
SPA3484 dppD; dipeptide transport ATP-binding protein DppD [KO:K12371 ]
SPA3483 dppF; dipeptide transport ATP-binding protein DppF [KO:K12372 ]
SPA1192 sapA; peptide transport periplasmic protein SapA precursor [KO:K19226 ]
SPA1191 sapB; peptide transport system permease protein SapB [KO:K19227 ]
SPA1182 sapC; peptide transport system permease protein SapC [KO:K19228 ]
SPA1181 sapD; peptide transport system ATP-binding protein SapD [KO:K19229 ]
SPA1180 sapF; peptide transport system ATP-binding protein SapF [KO:K19230 ]
SPA1906 yliB; putative ABC transporter periplasmic binding protein [KO:K13889 ]
SPA1905 yliC; hypothetical ABC transporter permease protein [KO:K13890 ]
SPA1904 yliD; hypothetical ABC transporter permease protein [KO:K13891 ]
SPA1907 yliA; hypothetical ABC transporter ATP-binding protein [KO:K13892 ]
SPA0635 yejA; putative transport system periplasmic binding protein [KO:K13893 ]
SPA0634 yejB; putative binding-protein-dependent transporter [KO:K13894 ]
SPA0633 yejE; putative binding-protein-dependent transporter [KO:K13895 ]
SPA0632 yejF; putative ABC-transporter ATP-binding protein [KO:K13896 ]
SPA2140 fepB; ferrienterobactin-binding periplasmic protein precursor [KO:K23185 ]
SPA2142 fepD; ferric enterobactin transport protein FepD [KO:K23186 ]
SPA2143 fepG; ferric enterobactin transport protein FepG [KO:K23187 ]
SPA0199 fhuD; ferrichrome-binding periplasmic protein precursor [KO:K23227 ]
SPA0200 fhuB; ferrichrome transport protein FhuB precursor [KO:K23228 ]
SPA0978 yebL; high-affinity zinc uptake system periplasmic binding protein [KO:K09815 ]
SPA0976 yebI; high-affinity zinc uptake system membrane protein [KO:K09816 ]
SPA2719 sitA; Iron transport protein, periplasmic-binding protein [KO:K11604 ]
SPA2721 sitC; Iron transport protein, inner membrane component [KO:K11605 ]
SPA2722 sitD; Iron transport protein, inner membrane component [KO:K11606 ]
SPA2720 sitB; Iron transport protein, ATP-binding component [KO:K11607 ]
SPA0848 cbiM; synthesis of vitamin B12 adenosyl cobalamide precursor [KO:K02007 ]
SPA0851 cbiO; putative cobalt transport ATP-binding protein CbiO [KO:K02006 ]
SPA2945 possible ABC-transport protein, ATP-binding component [KO:K16786 ] [EC:7.-.-.-]
SPA2946 possible ABC-transport protein, ATP-binding component [KO:K16787 ] [EC:7.-.-.-]
SPA3920 yneA; putative ABC transport protein, solute-binding component [KO:K10555 ]
SPA3918 ydeY; putative ABC transporter permease protein [KO:K10556 ]
SPA3919 ydeZ; putative ABC transporter, membrane component [KO:K10557 ]
SPA3917 ego; putative ABC transporter ATP-binding protein [KO:K10558 ]
SPA1633 ycfU; ABC transporter integral membrane subunit [KO:K09808 ]
SPA1631 ycfW; ABC transporter integral membrane subunit [KO:K09808 ]
SPA1632 ycfV; ABC transporter ATP-binding subunit [KO:K09810 ] [EC:7.6.2.-]
SPA2262 mdlA; putative ABC transporter ATP-binding membrane protein [KO:K18889 ]
SPA2261 mdlB; putative ABC transporter ATP-binding membrane protein [KO:K18890 ]
SPA2550 putative type I secretion protein, ATP-binding protein [KO:K12541 ]
SPA1857 ybjZ; conserved hypothetical ABC transporter [KO:K05685 ] [EC:7.6.2.-]
SPA0601 yojI; putative ABC transporter ATP-binding protein [KO:K06159 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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