KEGG   PATHWAY: tmz00280
Entry
tmz00280                    Pathway                                
Name
Valine, leucine and isoleucine degradation - Thauera aminoaromatica
Class
Metabolism; Amino acid metabolism
Pathway map
tmz00280  Valine, leucine and isoleucine degradation
tmz00280

Module
tmz_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:tmz00280]
Other DBs
GO: 0006550 0006552 0006574
Organism
Thauera aminoaromatica [GN:tmz]
Gene
Tmz1t_1209  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
Tmz1t_1037  Glu/Leu/Phe/Val dehydrogenase dimerisation region [KO:K00263] [EC:1.4.1.9]
Tmz1t_1967  pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit [KO:K00166] [EC:1.2.4.4]
Tmz1t_1966  Transketolase central region [KO:K00167] [EC:1.2.4.4]
Tmz1t_1965  Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase [KO:K09699] [EC:2.3.1.168]
Tmz1t_2542  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Tmz1t_3197  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Tmz1t_0733  acyl-CoA dehydrogenase domain protein [KO:K00248] [EC:1.3.8.1]
Tmz1t_0408  acyl-CoA dehydrogenase domain protein [KO:K00249] [EC:1.3.8.7]
Tmz1t_0748  acyl-CoA dehydrogenase domain protein [KO:K00253] [EC:1.3.8.4]
Tmz1t_0876  Enoyl-CoA hydratase/isomerase [KO:K01692] [EC:4.2.1.17]
Tmz1t_0807  3-hydroxyacyl-CoA dehydrogenase NAD-binding [KO:K01782] [EC:1.1.1.35 4.2.1.17 5.1.2.3]
Tmz1t_0409  acetyl-CoA acetyltransferase [KO:K00632] [EC:2.3.1.16]
Tmz1t_0810  acetyl-CoA acetyltransferase [KO:K00632] [EC:2.3.1.16]
Tmz1t_3483  acetyl-CoA carboxylase, biotin carboxylase [KO:K01965] [EC:6.4.1.3]
Tmz1t_3484  carboxyl transferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Tmz1t_3486  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
Tmz1t_0429  4-aminobutyrate aminotransferase [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
Tmz1t_0751  Carbamoyl-phosphate synthase L chain ATP-binding [KO:K01968] [EC:6.4.1.4]
Tmz1t_0749  Methylcrotonoyl-CoA carboxylase [KO:K01969] [EC:6.4.1.4]
Tmz1t_0750  Enoyl-CoA hydratase/isomerase [KO:K13766] [EC:4.2.1.18]
Tmz1t_1507  Enoyl-CoA hydratase/isomerase [KO:K13766] [EC:4.2.1.18]
Tmz1t_0753  pyruvate carboxyltransferase [KO:K01640] [EC:4.1.3.4]
Tmz1t_1658  acetoacetyl-CoA synthase [KO:K01907] [EC:6.2.1.16]
Tmz1t_0732  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tmz1t_0806  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tmz1t_2491  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tmz1t_2659  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Compound
C00024  Acetyl-CoA
C00068  Thiamin diphosphate
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00164  Acetoacetate
C00183  L-Valine
C00233  4-Methyl-2-oxopentanoate
C00332  Acetoacetyl-CoA
C00349  2-Methyl-3-oxopropanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00407  L-Isoleucine
C00630  2-Methylpropanoyl-CoA
C00671  (S)-3-Methyl-2-oxopentanoic acid
C00683  (S)-Methylmalonyl-CoA
C01205  (R)-3-Amino-2-methylpropanoate
C01213  (R)-Methylmalonyl-CoA
C02170  Methylmalonate
C02939  3-Methylbutanoyl-CoA
C03069  3-Methylcrotonyl-CoA
C03231  3-Methylglutaconyl-CoA
C03284  L-3-Aminoisobutanoate
C03344  2-Methylacetoacetyl-CoA
C03345  2-Methylbut-2-enoyl-CoA
C03460  2-Methylprop-2-enoyl-CoA
C04405  (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA
C05996  Branched chain fatty acid
C05998  3-Hydroxyisovaleryl-CoA
C06000  (S)-3-Hydroxyisobutyryl-CoA
C06001  (S)-3-Hydroxyisobutyrate
C06002  (S)-Methylmalonate semialdehyde
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C15974  3-Methyl-1-hydroxybutyl-ThPP
C15975  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysine
C15976  2-Methyl-1-hydroxypropyl-ThPP
C15977  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine
C15978  2-Methyl-1-hydroxybutyl-ThPP
C15979  [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine
C15980  (S)-2-Methylbutanoyl-CoA
C20827  3-Hydroxyisovalerate
Related
pathway
tmz00020  Citrate cycle (TCA cycle)
tmz00240  Pyrimidine metabolism
tmz00290  Valine, leucine and isoleucine biosynthesis
tmz00640  Propanoate metabolism
tmz00900  Terpenoid backbone biosynthesis
KO pathway
ko00280   
LinkDB

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