KEGG   PATHWAY: vpo03060
Entry
vpo03060                    Pathway                                
Name
Protein export - Vanderwaltozyma polyspora
Description
The protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the general protein export system that transports newly synthesized proteins into or across the cell membrane. The translocation channel is formed from a conserved trimeric membrane protein complex, called the Sec61/SecY complex. The twin-arginine translocation (Tat) pathway is another protein transport system that transports folded proteins in bacteria, archaea, and chloroplasts. Many Tat systems comprise three functionally different membrane proteins, TatA, TatB, and TatC, but TatA and TatE seem to have overlapping functions, with TatA having by far the more important role.
Class
Genetic Information Processing; Folding, sorting and degradation
Pathway map
vpo03060  Protein export
vpo03060

Other DBs
GO: 0043952 0043953
Organism
Vanderwaltozyma polyspora [GN:vpo]
Gene
Kpol_1055p34  hypothetical protein [KO:K03217]
Kpol_538p10  hypothetical protein [KO:K03106] [EC:3.6.5.4]
Kpol_194p2  hypothetical protein [KO:K10956]
Kpol_530p15  hypothetical protein [KO:K09481]
Kpol_1030p42  hypothetical protein [KO:K09481]
Kpol_1055p46  hypothetical protein [KO:K07342]
Kpol_1055p43  hypothetical protein [KO:K07342]
Kpol_1048p44  hypothetical protein [KO:K12275]
Kpol_1072p4  hypothetical protein [KO:K09540]
Kpol_1004p11  hypothetical protein [KO:K09490] [EC:3.6.4.10]
Kpol_1043p9  hypothetical protein [KO:K03104]
Kpol_1065p2  hypothetical protein [KO:K03108]
Kpol_1060p28  hypothetical protein [KO:K03107]
Kpol_541p8  hypothetical protein [KO:K03105]
Kpol_1023p54  hypothetical protein [KO:K13431]
Kpol_1032p92  hypothetical protein [KO:K12272]
Kpol_1032p81  hypothetical protein [KO:K01551] [EC:7.3.2.7 7.3.-.-]
Kpol_1037p43  hypothetical protein [KO:K23387]
Kpol_1066p41  hypothetical protein [KO:K23388]
Kpol_1032p8  hypothetical protein [KO:K16365]
Kpol_1037p26  hypothetical protein [KO:K16365]
Kpol_1025p44  hypothetical protein [KO:K22384]
Kpol_411p4  hypothetical protein [KO:K22386]
Kpol_1030p4  hypothetical protein [KO:K27163]
Kpol_1023p20  hypothetical protein [KO:K27164]
Kpol_1065p22  hypothetical protein [KO:K27165]
Kpol_1010p35  hypothetical protein [KO:K12946] [EC:3.4.-.-]
Kpol_1014p1  hypothetical protein [KO:K12947] [EC:3.4.-.-]
Kpol_1023p16  hypothetical protein [KO:K12948] [EC:3.4.-.-]
Kpol_1043p4  hypothetical protein [KO:K09647] [EC:3.4.21.-]
Kpol_1013p19  hypothetical protein [KO:K09648] [EC:3.4.21.-]
Reference
  Authors
Dalbey RE, Robinson C.
  Title
Protein translocation into and across the bacterial plasma membrane and the plant thylakoid membrane.
  Journal
Trends Biochem Sci 24:17-22 (1999)
DOI:10.1016/S0968-0004(98)01333-4
Reference
  Authors
Berks BC, Sargent F, Palmer T.
  Title
The Tat protein export pathway.
  Journal
Mol Microbiol 35:260-74 (2000)
DOI:10.1046/j.1365-2958.2000.01719.x
Reference
  Authors
Wexler M, Sargent F, Jack RL, Stanley NR, Bogsch EG, Robinson C, Berks BC, Palmer T.
  Title
TatD is a cytoplasmic protein with DNase activity. No requirement for TatD family proteins in sec-independent protein export.
  Journal
J Biol Chem 275:16717-22 (2000)
DOI:10.1074/jbc.M000800200
Reference
  Authors
Jongbloed JD, Martin U, Antelmann H, Hecker M, Tjalsma H, Venema G, Bron S, van Dijl JM, Muller J.
  Title
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway.
  Journal
J Biol Chem 275:41350-7 (2000)
DOI:10.1074/jbc.M004887200
Reference
  Authors
Rapoport TA
  Title
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes.
  Journal
Nature 450:663-9 (2007)
DOI:10.1038/nature06384
Reference
  Authors
Flower AM
  Title
The SecY translocation complex: convergence of genetics and structure.
  Journal
Trends Microbiol 15:203-10 (2007)
DOI:10.1016/j.tim.2007.03.001
Reference
  Authors
Osborne AR, Rapoport TA, van den Berg B
  Title
Protein translocation by the Sec61/SecY channel.
  Journal
Annu Rev Cell Dev Biol 21:529-50 (2005)
DOI:10.1146/annurev.cellbio.21.012704.133214
Reference
  Authors
Paetzel M, Karla A, Strynadka NC, Dalbey RE
  Title
Signal peptidases.
  Journal
Chem Rev 102:4549-80 (2002)
DOI:10.1021/cr010166y
Reference
  Authors
Paetzel M, Dalbey RE, Strynadka NC
  Title
The structure and mechanism of bacterial type I signal peptidases. A novel antibiotic target.
  Journal
Pharmacol Ther 87:27-49 (2000)
DOI:10.1016/S0163-7258(00)00064-4
Reference
  Authors
Ng SY, Chaban B, VanDyke DJ, Jarrell KF
  Title
Archaeal signal peptidases.
  Journal
Microbiology 153:305-14 (2007)
DOI:10.1099/mic.0.2006/003087-0
Reference
  Authors
Desvaux M, Hebraud M, Talon R, Henderson IR
  Title
Secretion and subcellular localizations of bacterial proteins: a semantic awareness issue.
  Journal
Trends Microbiol 17:139-45 (2009)
DOI:10.1016/j.tim.2009.01.004
Reference
  Authors
Nakatogawa H, Murakami A, Ito K
  Title
Control of SecA and SecM translation by protein secretion.
  Journal
Curr Opin Microbiol 7:145-50 (2004)
DOI:10.1016/j.mib.2004.01.001
KO pathway
ko03060   
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