KEGG   PATHWAY: zof00480
Entry
zof00480                    Pathway                                
Name
Glutathione metabolism - Zingiber officinale (ginger)
Class
Metabolism; Metabolism of other amino acids
Pathway map
zof00480  Glutathione metabolism
zof00480

Module
zof_M00118  Glutathione biosynthesis, glutamate => glutathione [PATH:zof00480]
Other DBs
GO: 0006749
Organism
Zingiber officinale (ginger) [GN:zof]
Gene
121976862  glutathione hydrolase 3-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
122032230  glutathione hydrolase 1-like isoform X1 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
122034940  glutathione hydrolase 1-like isoform X1 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
121971815  glutathione hydrolase 3-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
122017718  gamma-glutamylcyclotransferase 2-2-like [KO:K22596] [EC:4.3.2.9]
122006697  gamma-glutamylcyclotransferase 2-3 isoform X1 [KO:K22596] [EC:4.3.2.9]
122009310  gamma-glutamylcyclotransferase 2-2-like [KO:K22596] [EC:4.3.2.9]
122032180  gamma-glutamylcyclotransferase 2-1-like [KO:K22596] [EC:4.3.2.9]
122020038  gamma-glutamylcyclotransferase 2-2-like [KO:K22596] [EC:4.3.2.9]
122034775  gamma-glutamylcyclotransferase 2-1-like [KO:K22596] [EC:4.3.2.9]
122034776  gamma-glutamylcyclotransferase 2-2-like [KO:K22596] [EC:4.3.2.9]
122022609  gamma-glutamylcyclotransferase 2-2-like [KO:K22596] [EC:4.3.2.9]
122002445  gamma-glutamylcyclotransferase 2-3-like isoform X1 [KO:K22596] [EC:4.3.2.9]
122047430  5-oxoprolinase-like [KO:K01469] [EC:3.5.2.9]
122015773  5-oxoprolinase-like [KO:K01469] [EC:3.5.2.9]
122019803  glutamate--cysteine ligase A, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
122023656  glutamate--cysteine ligase A, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
122020776  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
122024469  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
122031208  leucine aminopeptidase 1-like [KO:K01255] [EC:3.4.11.1]
121972385  leucine aminopeptidase 1-like [KO:K01255] [EC:3.4.11.1]
122043099  puromycin-sensitive aminopeptidase-like isoform X1 [KO:K01256] [EC:3.4.11.2]
122047602  puromycin-sensitive aminopeptidase-like isoform X1 [KO:K01256] [EC:3.4.11.2]
122041382  glutathione S-transferase U18-like [KO:K00799] [EC:2.5.1.18]
122041383  glutathione S-transferase U15-like [KO:K00799] [EC:2.5.1.18]
122041395  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
122041400  glutathione S-transferase U15-like [KO:K00799] [EC:2.5.1.18]
122041401  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
122056657  protein IN2-1 homolog B-like [KO:K00799] [EC:2.5.1.18]
122004796  glutathione S-transferase F10-like [KO:K00799] [EC:2.5.1.18]
122026213  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
122042260  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122042515  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
121989071  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
121989187  protein IN2-1 homolog B-like [KO:K00799] [EC:2.5.1.18]
122005180  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
122026498  uncharacterized protein LOC122026498 [KO:K00799] [EC:2.5.1.18]
122027129  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122027145  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122027154  probable glutathione S-transferase parC [KO:K00799] [EC:2.5.1.18]
122027155  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
122027194  glutathione S-transferase U25-like isoform X1 [KO:K00799] [EC:2.5.1.18]
121989418  protein IN2-1 homolog B-like [KO:K00799] [EC:2.5.1.18]
122005663  glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
122027576  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
122027799  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
122044464  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
122028162  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
122028570  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122028577  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
122045442  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
122007887  glutathione S-transferase U15-like [KO:K00799] [EC:2.5.1.18]
122007893  probable glutathione S-transferase GSTU6 isoform X1 [KO:K00799] [EC:2.5.1.18]
122007894  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
122029537  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
122029565  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122029773  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122029793  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
122029814  glutathione S-transferase U25-like [KO:K00799] [EC:2.5.1.18]
122029864  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
122045880  glutathione S-transferase U15-like [KO:K00799] [EC:2.5.1.18]
122045893  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
122045898  glutathione S-transferase U15-like [KO:K00799] [EC:2.5.1.18]
122045899  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
121977511  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
122030234  probable glutathione S-transferase parC [KO:K00799] [EC:2.5.1.18]
122030330  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122046783  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
121979323  glutathione S-transferase U19-like [KO:K00799] [EC:2.5.1.18]
122008977  glutathione S-transferase F8, chloroplastic-like [KO:K00799] [EC:2.5.1.18]
122008984  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
122009110  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
121980625  glutathione S-transferase F8, chloroplastic-like [KO:K00799] [EC:2.5.1.18]
121980691  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
121981429  glutathione S-transferase T1-like isoform X1 [KO:K00799] [EC:2.5.1.18]
122049184  glutathione S-transferase U18-like [KO:K00799] [EC:2.5.1.18]
122049517  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
122011537  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
122011538  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
122011539  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
122011540  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
122011609  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
121982577  glutathione S-transferase F10-like [KO:K00799] [EC:2.5.1.18]
121982587  glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
121982888  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
121982951  glutathione S-transferase U9-like [KO:K00799] [EC:2.5.1.18]
121998022  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
121998134  protein IN2-1 homolog B-like [KO:K00799] [EC:2.5.1.18]
122052168  protein IN2-1 homolog B-like [KO:K00799] [EC:2.5.1.18]
121998368  protein IN2-1 homolog B-like [KO:K00799] [EC:2.5.1.18]
122020922  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
122021452  glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
121971313  glutathione S-transferase F10-like [KO:K00799] [EC:2.5.1.18]
121985307  glutathione S-transferase T1-like [KO:K00799] [EC:2.5.1.18]
122001366  glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
122015584  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
122023641  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
122038196  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
122055147  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122055148  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
122015876  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
122015886  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
121973279  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
121987203  glutathione S-transferase F10-like [KO:K00799] [EC:2.5.1.18]
121987463  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
121987527  glutathione S-transferase U9-like [KO:K00799] [EC:2.5.1.18]
122002887  glutathione S-transferase F10-like [KO:K00799] [EC:2.5.1.18]
122016598  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
122016649  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
122016712  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
122016982  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
122016984  glutathione S-transferase U15-like isoform X1 [KO:K00799] [EC:2.5.1.18]
121989275  probable glutathione S-transferase DHAR2, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
122006961  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
122038808  probable glutathione S-transferase DHAR2, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
122002718  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
122056082  glutathione reductase, cytosolic-like [KO:K00383] [EC:1.8.1.7]
121975802  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
122006420  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
122051555  glutathione reductase, cytosolic-like [KO:K00383] [EC:1.8.1.7]
121970719  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
122002171  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
122045248  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
121991882  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
121980045  isocitrate dehydrogenase [NADP] [KO:K00031] [EC:1.1.1.42]
121993147  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
121995788  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
121997111  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
122020347  cytosolic isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
122051877  cytosolic isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
121984118  isocitrate dehydrogenase [NADP] [KO:K00031] [EC:1.1.1.42]
122040707  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
122056719  6-phosphogluconate dehydrogenase, decarboxylating 2 isoform X1 [KO:K00033] [EC:1.1.1.44 1.1.1.343]
121989114  6-phosphogluconate dehydrogenase, decarboxylating 1-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
122006864  6-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
121981572  6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
121998075  6-phosphogluconate dehydrogenase, decarboxylating 1 [KO:K00033] [EC:1.1.1.44 1.1.1.343]
122052231  6-phosphogluconate dehydrogenase, decarboxylating 2-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
121985452  6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
122002622  6-phosphogluconate dehydrogenase, decarboxylating 1, chloroplastic-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
122041726  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122017303  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122025597  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122005345  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122026902  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122045616  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122046248  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122048897  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122021834  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122001060  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122041113  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
122056756  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
122002990  probable glutathione peroxidase 5 isoform X1 [KO:K00432] [EC:1.11.1.9]
122017625  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
121988959  probable glutathione peroxidase 2 [KO:K00432] [EC:1.11.1.9]
121989331  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
121991290  probable glutathione peroxidase 4 [KO:K00432] [EC:1.11.1.9]
122007241  probable glutathione peroxidase 5 isoform X1 [KO:K00432] [EC:1.11.1.9]
121992578  putative glutathione peroxidase 7, chloroplastic [KO:K00432] [EC:1.11.1.9]
122008539  probable glutathione peroxidase 2 [KO:K00432] [EC:1.11.1.9]
121996535  phospholipid hydroperoxide glutathione peroxidase 1, chloroplastic-like [KO:K00432] [EC:1.11.1.9]
122050443  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
121997399  probable glutathione peroxidase 4 [KO:K00432] [EC:1.11.1.9]
121997904  probable glutathione peroxidase 2 [KO:K00432] [EC:1.11.1.9]
122012672  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
122052268  probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial [KO:K00432] [EC:1.11.1.9]
121998278  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
122015881  probable glutathione peroxidase 2 isoform X1 [KO:K00432] [EC:1.11.1.9]
122005156  1-Cys peroxiredoxin PER1-like [KO:K11188] [EC:1.11.1.7 1.11.1.27 3.1.1.-]
121999897  1-Cys peroxiredoxin PER1-like [KO:K11188] [EC:1.11.1.7 1.11.1.27 3.1.1.-]
121991916  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121993106  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121980597  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121995822  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
122010257  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
121997084  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
121984508  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
122016491  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
121988513  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
121988808  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
121988809  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
122005309  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
122019986  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
121976899  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
122007419  L-ascorbate peroxidase 2, cytosolic-like [KO:K00434] [EC:1.11.1.11]
122008331  L-ascorbate peroxidase 2, cytosolic-like [KO:K00434] [EC:1.11.1.11]
121997389  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
122051428  L-ascorbate peroxidase, cytosolic-like [KO:K00434] [EC:1.11.1.11]
121968459  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
121982423  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
122052343  probable L-ascorbate peroxidase 4, peroxisomal isoform X1 [KO:K00434] [EC:1.11.1.11]
122021044  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
122014382  L-ascorbate peroxidase 2, cytosolic-like [KO:K00434] [EC:1.11.1.11]
122001029  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
121971860  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
122024395  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
121986318  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
121988619  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
121991862  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
121992211  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
121996149  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
121997500  ribonucleoside-diphosphate reductase large subunit-like isoform X1 [KO:K10807] [EC:1.17.4.1]
122038993  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
121987902  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
122026089  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
122026146  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
122028565  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
122028587  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
122050308  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
121982222  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
121982234  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
121983346  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
122054747  ribonucleoside-diphosphate reductase small chain C-like [KO:K10808] [EC:1.17.4.1]
122055332  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
121986119  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
Compound
C00005  NADPH
C00006  NADP+
C00024  Acetyl-CoA
C00025  L-Glutamate
C00037  Glycine
C00051  Glutathione
C00072  Ascorbate
C00077  L-Ornithine
C00097  L-Cysteine
C00127  Glutathione disulfide
C00134  Putrescine
C00151  L-Amino acid
C00315  Spermidine
C00669  gamma-L-Glutamyl-L-cysteine
C00750  Spermine
C01322  RX
C01419  Cys-Gly
C01672  Cadaverine
C01879  5-Oxoproline
C02090  Trypanothione
C02320  R-S-Glutathione
C03170  Trypanothione disulfide
C03646  Bis-gamma-glutamylcystine
C03740  (5-L-Glutamyl)-L-amino acid
C05422  Dehydroascorbate
C05726  S-Substituted L-cysteine
C05727  S-Substituted N-acetyl-L-cysteine
C05729  R-S-Cysteinylglycine
C05730  Glutathionylspermidine
C16562  Glutathionylspermine
C16563  Bis(glutathionyl)spermine
C16564  Bis(glutathionyl)spermine disulfide
C16565  Aminopropylcadaverine
C16566  Glutathionylaminopropylcadaverine
C16567  Homotrypanothione
C16568  Homotrypanothione disulfide
C16663  Tryparedoxin
C16664  Tryparedoxin disulfide
Reference
PMID:12675513
  Authors
Josch C, Klotz LO, Sies H.
  Title
Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver.
  Journal
Biol Chem 384:213-8 (2003)
DOI:10.1515/BC.2003.023
Reference
PMID:18482986
  Authors
Chu L, Lai Y, Xu X, Eddy S, Yang S, Song L, Kolodrubetz D.
  Title
A 52-kDa leucyl aminopeptidase from treponema denticola is a cysteinylglycinase that mediates the second step of glutathione metabolism.
  Journal
J Biol Chem 283:19351-8 (2008)
DOI:10.1074/jbc.M801034200
Reference
PMID:14583094
  Authors
Cappiello M, Lazzarotti A, Buono F, Scaloni A, D'Ambrosio C, Amodeo P, Mendez BL, Pelosi P, Del Corso A, Mura U.
  Title
New role for leucyl aminopeptidase in glutathione turnover.
  Journal
Biochem J 378:35-44 (2004)
DOI:10.1042/BJ20031336
Reference
PMID:11157967
  Authors
Suzuki H, Kamatani S, Kim ES, Kumagai H.
  Title
Aminopeptidases A, B, and N and dipeptidase D are the four cysteinylglycinases of Escherichia coli K-12.
  Journal
J Bacteriol 183:1489-90 (2001)
DOI:10.1128/JB.183.4.1489-1490.2001
Reference
PMID:15610825
  Authors
Oza SL, Shaw MP, Wyllie S, Fairlamb AH.
  Title
Trypanothione biosynthesis in Leishmania major.
  Journal
Mol Biochem Parasitol 139:107-16 (2005)
DOI:10.1016/j.molbiopara.2004.10.004
Reference
PMID:12049631
  Authors
Oza SL, Ariyanayagam MR, Fairlamb AH.
  Title
Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculata.
  Journal
Biochem J 364:679-86 (2002)
DOI:10.1042/BJ20011370
Reference
PMID:9677355
  Authors
Tetaud E, Manai F, Barrett MP, Nadeau K, Walsh CT, Fairlamb AH.
  Title
Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata.
  Journal
J Biol Chem 273:19383-90 (1998)
DOI:10.1074/jbc.273.31.19383
Reference
PMID:12750367
  Authors
Ariyanayagam MR, Oza SL, Mehlert A, Fairlamb AH.
  Title
Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi.
  Journal
J Biol Chem 278:27612-9 (2003)
DOI:10.1074/jbc.M302750200
Reference
PMID:12967709
  Authors
Oza SL, Ariyanayagam MR, Aitcheson N, Fairlamb AH.
  Title
Properties of trypanothione synthetase from Trypanosoma brucei.
  Journal
Mol Biochem Parasitol 131:25-33 (2003)
DOI:10.1016/S0166-6851(03)00176-2
Reference
PMID:12121990
  Authors
Oza SL, Tetaud E, Ariyanayagam MR, Warnon SS, Fairlamb AH.
  Title
A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.
  Journal
J Biol Chem 277:35853-61 (2002)
DOI:10.1074/jbc.M204403200
Reference
PMID:15537651
  Authors
Comini M, Menge U, Wissing J, Flohe L.
  Title
Trypanothione synthesis in crithidia revisited.
  Journal
J Biol Chem 280:6850-60 (2005)
DOI:10.1074/jbc.M404486200
Reference
PMID:7813456
  Authors
Hunter KJ, Le Quesne SA, Fairlamb AH.
  Title
Identification and biosynthesis of N1,N9-bis(glutathionyl)aminopropylcadaverine (homotrypanothione) in Trypanosoma cruzi.
  Journal
Eur J Biochem 226:1019-27 (1994)
DOI:10.1111/j.1432-1033.1994.t01-1-01019.x
Reference
PMID:12751784
  Authors
Krauth-Siegel RL, Meiering SK, Schmidt H.
  Title
The parasite-specific trypanothione metabolism of trypanosoma and leishmania.
  Journal
Biol Chem 384:539-49 (2003)
DOI:10.1515/BC.2003.062
Reference
PMID:18395526
  Authors
Krauth-Siegel RL, Comini MA.
  Title
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism.
  Journal
Biochim Biophys Acta 1780:1236-48 (2008)
DOI:10.1016/j.bbagen.2008.03.006
Reference
PMID:8892297
  Authors
Krauth-Siegel RL, Ludemann H.
  Title
Reduction of dehydroascorbate by trypanothione.
  Journal
Mol Biochem Parasitol 80:203-8 (1996)
DOI:10.1016/0166-6851(96)02689-8
Reference
PMID:11150302
  Authors
Dormeyer M, Reckenfelderbaumer N, Ludemann H, Krauth-Siegel RL.
  Title
Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase.
  Journal
J Biol Chem 276:10602-6 (2001)
DOI:10.1074/jbc.M010352200
Reference
PMID:12949079
  Authors
Schmidt H, Krauth-Siegel RL.
  Title
Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei.
  Journal
J Biol Chem 278:46329-36 (2003)
DOI:10.1074/jbc.M305338200
Reference
PMID:9851611
  Authors
Tetaud E, Fairlamb AH.
  Title
Cloning, expression and reconstitution of the trypanothione-dependent peroxidase system of Crithidia fasciculata.
  Journal
Mol Biochem Parasitol 96:111-23 (1998)
DOI:10.1016/S0166-6851(98)00120-0
Reference
PMID:12446213
  Authors
Castro H, Sousa C, Santos M, Cordeiro-da-Silva A, Flohe L, Tomas AM.
  Title
Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum.
  Journal
Free Radic Biol Med 33:1552-62 (2002)
DOI:10.1016/S0891-5849(02)01089-4
Reference
PMID:10713147
  Authors
Wilkinson SR, Temperton NJ, Mondragon A, Kelly JM.
  Title
Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi.
  Journal
J Biol Chem 275:8220-5 (2000)
DOI:10.1074/jbc.275.11.8220
Reference
PMID:17922848
  Authors
Konig J, Fairlamb AH.
  Title
A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major.
  Journal
FEBS J 274:5643-58 (2007)
DOI:10.1111/j.1742-4658.2007.06087.x
Reference
PMID:12466271
  Authors
Hillebrand H, Schmidt A, Krauth-Siegel RL.
  Title
A second class of peroxidases linked to the trypanothione metabolism.
  Journal
J Biol Chem 278:6809-15 (2003)
DOI:10.1074/jbc.M210392200
Reference
PMID:14982633
  Authors
Soksawatmaekhin W, Kuraishi A, Sakata K, Kashiwagi K, Igarashi K.
  Title
Excretion and uptake of cadaverine by CadB and its physiological functions in Escherichia coli.
  Journal
Mol Microbiol 51:1401-12 (2004)
DOI:10.1046/j.1365-2958.2003.03913.x
Reference
PMID:6798961
  Authors
Pegg AE, Shuttleworth K, Hibasami H.
  Title
Specificity of mammalian spermidine synthase and spermine synthase.
  Journal
Biochem J 197:315-20 (1981)
DOI:10.1042/bj1970315
Related
pathway
zof00220  Arginine biosynthesis
zof00250  Alanine, aspartate and glutamate metabolism
zof00270  Cysteine and methionine metabolism
zof00430  Taurine and hypotaurine metabolism
zof00460  Cyanoamino acid metabolism
KO pathway
ko00480   
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