Prionailurus bengalensis (leopard cat): 122468215
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Entry
122468215 CDS
T07574
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg00230
Purine metabolism
pbg01100
Metabolic pathways
pbg04927
Cortisol synthesis and secretion
pbg04934
Cushing syndrome
pbg05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122468215 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
122468215 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122468215 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
122468215 (PDE8A)
Enzymes [BR:
pbg01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
122468215 (PDE8A)
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GFIT
Motif
Pfam:
PDEase_I
PAS
PAS_9
PAS_4
PDE8
PAS_3
PAS_8
DUF5894
Sina_ZnF
Response_reg
Motif
Other DBs
NCBI-GeneID:
122468215
NCBI-ProteinID:
XP_043410604
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Position
B3:complement(4612413..4767014)
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AA seq
836 aa
AA seq
DB search
MGCAPSIHISEGRAAYHGGKEAEDAPGAAAAPPPPAGPRLPPGQKTTASPGARGAGLAES
EPRDGSGRKVAIADVQFGPMRFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEA
QAVLACFLDKHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTIIIGVVRRTDREESSVM
PLIAAGFTRRYVENPSLMACYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAVEITSE
DRVIQYANPAFETTMGYQAGELIGKELAEVPVNEKKAELLDTINSCIRIGKEWQGIYHAK
KKNGDNVQQNVKIVPVVGQGGKIRHYVSIIRVCNGNNKAEKRTESVQSDPHTDNQSGKHK
DRRKSSLDVRAVASRASEVSSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTE
ALDRVLEILRTTELYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKSLQQVPG
SVVTPISLHDIPPRIARAMENEEYWDFDIFELEAATHKRPLIYLGLKMFARFGICEFLNC
SEATLRSWLQIIEANYHSCNPYHNSTHSADVLHATAYFLCKERIKQTLDPVDEVAALIAA
TIHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTRDDTCNIFKNMERND
YRTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLAALEENEETNKDEEAINTMLRTPEN
RTLIKRMLIKCADVSNPCRPLEQCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCS
IPKSQISFIDYFITDMFDAWDAFVDLPELMQHLDNNFKYWKGLDEMQLRSLRPPPE
NT seq
2511 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcaccgagcatccacatttccgagggccgggcggcttaccacggcggcaag
gaggccgaggacgcgccgggcgccgccgccgcgccgccgccgcccgccgggccgcgcctc
ccacccggccagaagaccaccgcctcgcccggggcccgcggtgccggcctcgcggagtcc
gagcctcgcgacggcagcggcaggaaggtagccattgctgacgtgcagtttggccccatg
agatttcatccagatcaactccaggtacttttagtgtttaccaaagaagataaccagtgt
aatggattctgcagggcgtgtgaaaaagcagggtttaagtgcacagttaccaaggaggcc
caggctgtccttgcctgtttcctggacaagcatcacgacatcatcatcatagaccacaga
aacccccgacagctggacgcggaggccctgtgcaggtctatcaggtcatcaaaactctcc
gaaaacacaattatcattggtgtagtacgcaggacggatagagaagagtcctctgtgatg
cccctcattgctgctggctttacaaggaggtatgtggaaaaccccagcctcatggcgtgt
tacaacgaactgctccagctggagttcggagaggtgcggtcccagctgaaactcagggct
tgtaactcaatattcactgcactggagaaaagtcaagaagcagttgaaattacaagtgaa
gaccgtgttatacagtatgcaaatcctgcgtttgaaacaaccatgggctatcaagcaggc
gaactaataggcaaggagttagcggaagtgcctgtaaatgaaaaaaaggctgagttgctc
gataccataaattcatgcatcaggataggcaaggagtggcaaggaatttaccacgccaaa
aagaaaaatggagacaacgtacaacagaacgtgaagatagtacctgtcgtcggacaggga
ggaaaaattagacactatgtgtccattatcagagtgtgcaacggcaacaataaggccgag
aaaagaactgaaagtgttcagtctgaccctcacacagataatcagtcaggcaaacacaaa
gacagaaggaaaagctcgctcgatgtcagagctgttgcctctcgagcaagtgaagtcagc
agccagagacggcactcctccatggcccggatacattccatgacgatcgaggcgcccatc
accaaggtaatcaacattatcaacgccgcccaggaaagcagccccatgcctgtgacagaa
gccttagaccgtgtgctggagattctgagaaccactgaattgtattcgccacagttcggt
gctaaggacgatgatcctcatgccaatgaccttgttggaggcttaatgtctgatggtttg
cgaagactatccgggaatgaatatgttctttcaacaaaaagcctgcagcaggtgcccggc
agtgttgtcacccccatctcccttcacgacatccctccccggatagctcgggctatggaa
aatgaagagtactgggactttgatatttttgaactggaggccgccacacataaaaggcct
ctgatctatcttggtctcaaaatgtttgcgcgctttggaatctgtgaattcttgaactgc
tctgaggcgacgctgagatcgtggctgcagattattgaagccaattaccattcttgtaac
ccctaccacaattccacacactctgccgacgtgcttcatgccactgcctatttcctctgc
aaagagaggataaagcaaacattagatccggtcgacgaggtcgccgccctcattgcagcc
accatccacgacgtggaccaccccgggaggaccaactccttcctgtgcaatgccggcagc
gagctggccatcctgtacaacgacactgccgtgctggagagccaccacgcggccctggcc
ttccagctgaccacccgcgatgacacatgcaatatcttcaaaaacatggagaggaatgac
tatcggacgctgcgccagggtattatcgacatggtcttggccacggaaatgacaaaacac
ttcgagcacgtcaacaaatttgtcaacagcatcaacaagcccctggcggcactagaagaa
aacgaggaaacgaataaagacgaagaagccataaacactatgctccggactccagagaac
cggactctgattaaacggatgctcatcaagtgtgcggacgtgtccaacccctgccgaccg
ctggagcagtgcatcgagtgggccgcacgcatatcagaagaatatttttctcagacggat
gaggagaagcagcaggacttgcccgtggtgatgccggtttttgacagaaacacctgcagc
atccccaaatcccagatctctttcattgactacttcatcacggacatgtttgatgcctgg
gacgcctttgtcgacctgcctgagctaatgcagcatcttgacaacaacttcaaatactgg
aaaggactggacgagatgcagctgcggagcctccggccgccccccgaatag
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