Prionailurus bengalensis (leopard cat): 122488640
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Entry
122488640 CDS
T07574
Symbol
INSR
Name
(RefSeq) LOW QUALITY PROTEIN: insulin receptor
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg04010
MAPK signaling pathway
pbg04014
Ras signaling pathway
pbg04015
Rap1 signaling pathway
pbg04022
cGMP-PKG signaling pathway
pbg04066
HIF-1 signaling pathway
pbg04068
FoxO signaling pathway
pbg04072
Phospholipase D signaling pathway
pbg04150
mTOR signaling pathway
pbg04151
PI3K-Akt signaling pathway
pbg04152
AMPK signaling pathway
pbg04211
Longevity regulating pathway
pbg04213
Longevity regulating pathway - multiple species
pbg04520
Adherens junction
pbg04910
Insulin signaling pathway
pbg04913
Ovarian steroidogenesis
pbg04923
Regulation of lipolysis in adipocytes
pbg04930
Type II diabetes mellitus
pbg04931
Insulin resistance
pbg04932
Non-alcoholic fatty liver disease
pbg04960
Aldosterone-regulated sodium reabsorption
pbg05010
Alzheimer disease
pbg05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122488640 (INSR)
04014 Ras signaling pathway
122488640 (INSR)
04015 Rap1 signaling pathway
122488640 (INSR)
04066 HIF-1 signaling pathway
122488640 (INSR)
04068 FoxO signaling pathway
122488640 (INSR)
04072 Phospholipase D signaling pathway
122488640 (INSR)
04022 cGMP-PKG signaling pathway
122488640 (INSR)
04151 PI3K-Akt signaling pathway
122488640 (INSR)
04152 AMPK signaling pathway
122488640 (INSR)
04150 mTOR signaling pathway
122488640 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
122488640 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
122488640 (INSR)
04923 Regulation of lipolysis in adipocytes
122488640 (INSR)
04913 Ovarian steroidogenesis
122488640 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
122488640 (INSR)
09149 Aging
04211 Longevity regulating pathway
122488640 (INSR)
04213 Longevity regulating pathway - multiple species
122488640 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
122488640 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
122488640 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
122488640 (INSR)
04932 Non-alcoholic fatty liver disease
122488640 (INSR)
04931 Insulin resistance
122488640 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122488640 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pbg04090
]
122488640 (INSR)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122488640 (INSR)
Protein kinases [BR:
pbg01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
122488640 (INSR)
CD molecules [BR:
pbg04090
]
Proteins
122488640 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
B2
DUF4476
Motif
Other DBs
NCBI-GeneID:
122488640
NCBI-ProteinID:
XP_043446161
LinkDB
All DBs
Position
A2:6351865..6494909
Genome browser
AA seq
1369 aa
AA seq
DB search
MGAGAGRGAATAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLVMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHGHCQKVCPTICKSHGCTADGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCRDLHNKCKNXRRQG
CHQYVIHNNRCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC
TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFVPRPSRKRRALADAGNVTAAVPTVPGFPNTSSSVPTSPE
EHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVSARTMPEAKADDI
VGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRL
RGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIG
SIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGS
FGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVV
SKGQPTLVVMELMVHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAK
KFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVF
TTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMHMCW
QFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLDRAS
HSQREEAGGRDGVSSLGLKRNYEDHIPYTHMNGGKKNGRILTLPRSNPS
NT seq
4109 nt
NT seq
+upstream
nt +downstream
nt
atgggcgccggggctgggcggggggcggccaccgcgccgctgctggtggcggtggccgcg
ctgctgctgggcgccgcgggccacctgtaccccggagaggtctgccctggcatggatatc
cggaacaacctgacgaggctgcacgaactggccaactgctcggtcattgaaggtcatttg
cagatactgctcatgttcaaaacgaggcccgaggacttccgagacctcagtttccccaaa
ctcgtcatgatcactgattacctgctgctcttccgggtgtacgggctggagagcctgaag
gacctcttccccaacctcacggtcatccggggctcgcgcctcttcttcaactacgcgctg
gtcatcttcgagatggtgcacctgaaggagcttggcctctacagcttgatgaacattacc
cggggctccgtccgcatcgagaagaataatgagctgtgctacctggccaccatcgactgg
tcgcgcatcctggattcggtggaggataattacattgtgttgaacaaagacgacaacgag
gagtgtggggacatttgtccaggcactgcaaagggcaagaccaactgccctgccactgtc
atcaacgggcagtttgtggagcgttgttggacacacggccattgccagaaagtttgtccg
accatctgcaagtcgcacggctgcacggccgacggcctctgctgccacagcgagtgtttg
ggcaactgctctgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg
gacggcaggtgcgtggagacctgcccgcccccctactaccacttccaagactggcgctgc
gtgaacttcagcttctgccgggacctgcacaataaatgcaagaactccggagacagggtt
gccaccagtatgtcattcacaacaacaggtgcatccctgagtgcccctcggggtacacga
tgaattccagcaacctcatgtgtactccctgcctgggcccctgtcccaaggtctgccaca
tcctggaaggcgagaagaccatcgactcggtgacatctgcccaggagctccgaggctgca
ccgtcgtcaacggaagcctaatcatcaacattcgagggggcaacaacctggcagctgagc
tggaggccaacctcggactcattgaagaaatttctgggtatctgaagatccgaagatcct
atgctcttgtgtcactttcctttttccggaagttacggctgattcggggagagaccttgg
aaatcgggaactactctttctatgccttggacaaccagaacctgaggcagctatgggact
ggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataatcccaaac
tctgcttgtcggaaattcacaagatggaggaggtttcaggaaccaaggggcgccaggagc
ggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaatgaactactta
aattttcttacattcggacatcttacgacaagatcttgctgaaatgggagccgtactggc
cccctgacttccgagacctccttggcttcatgctcttctacaaagaggccccttaccaga
atgtgaccgagttcgacgggcaggacgcgtgtggctccaacagctggacggtggtggaca
ttgacccgcctctgaggtccaatgaccccaagtcgcagaaccacccagggtggctgatgc
ggggtctcaagccctggacccagtatgccatctttgtcaagaccttggtcaccttttctg
atgagcgccgcacgtatggggccaagagtgacatcatctatgtccagaccgatgccacca
acccttccgtccccctggatcctatctcggtttcgaattcctcctctcagatcattctga
agtggaagcctccctcggaccccaatggcaacatcacgcactacctggtgttctgggaga
ggcaggcggaggacagcgagctgtatgagttggattattgcctcaaagggttgaagctgc
cttcccggacctggtccccgccgttcgagtccgagggctcccagaagcacaatcagagtg
aatacgaggagtccgctggcgaatgctgctcatgtcccaaaaccgactctcagatcctga
aggagctggaggagtcctctttcaggaagacgttcgaggattacctgcacaatgtggttt
tcgtgcccaggccgtcgcggaagcgcagggccctcgccgacgctgggaacgtgacggccg
ccgtgcccacggtgcctggtttccccaacacttccagcagcgtgcccacgagcccggaag
agcacaagcccttcgagaaggtggtgaacaaagagtcgctggtcatctccggcctgcgtc
acttcaccggctaccgcatcgagctgcaggcttgcaaccaagatgcccccgaggagaggt
gcagcgtggctgcctacgtcagcgccaggaccatgcccgaagccaaggcagacgacattg
ttggccctgtgacccatgaaatcttcgagaacaacgtggttcacctgatgtggcaagagc
ctaaagaacccaatggattgatcgtgctgtatgaagtgagttaccgacggtatggtgatg
aggagctgcacctctgtgtctcccgtagacactttgctctggagcgaggctgcaggctgc
gaggtctgccgccggggaattacagtgtgcgagttcgggccacctccctggcgggcaacg
gctcctggacagaagccacttatttctatgtgacagactatttagatgtcccatcgaaca
ttgcaaaaattatcatcgggcctctcatctttgtctttctcttcagtgttgtgattggaa
gtatttatctattcctgagaaagaggcagccggatggcccactggggccgctgtatgctt
cttcaaaccctgagtacctcagtgccagtgatgtgtttccctgctctgtgtatgtgccgg
acgagtgggaggtgcctcgggagaagatcactctcctgcgcgagctggggcagggctcct
tcggcatggtgtacgagggcaatgccagggacatcgtcaagggcgaggcggagacccgcg
tggcggtgaagacggtcaacgagtccgccagtctgcgagagaggatcgagtttctcaacg
aggcctcagtcatgaagggcttcacctgtcatcacgtggtccgcctcctgggggtggtgt
ccaaaggccagccgacgctggtggtgatggagctgatggttcacggagacctgaagagct
acctccgctccctgcggccggaggctgagaataaccctggccgccctccccctactctgc
aagagatgattcagatggcggcggagatcgccgacgggatggcgtacctgaatgccaaga
agtttgtgcaccgggatctcgcagctcgaaattgcatggtggcccacgacttcaccgtca
aaattggagacttcggaatgaccagagacatctatgaaacggattactaccggaaaggag
gcaagggtctgctccccgtgcggtggatggcaccggaatccctgaaggacggggtcttca
ccacttcttctgacatgtggtcctttggtgtggtcctttgggaaatcaccagcttggcgg
aacaaccttaccaaggcctgtctaatgaacaggtgttgaaatttgtcatggacggaggat
atttggaccaacctgacaactgtccggagagagtcaccgacctgatgcacatgtgctggc
agttcaatcccaagatgcggcccaccttcctggagatcgttgacctgctcaaggacgacc
tgcaccccagctttccggaagtttccttcttccacagcgaggagaacaaggcgcctgaga
gcgaggagttggaaatggagtttgaggacatggagagcgtccccctggatcgggcctcac
actcacagagggaagaggccgggggccgggatggagtgtcctcgctgggcctcaagcgca
actacgaggaccacatcccctacacccacatgaacgggggcaagaagaacgggcggatcc
tgaccctgccgaggtcgaatccttcctaa
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