Pseudonocardia broussonetiae: HOP40_11265
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Entry
HOP40_11265 CDS
T07210
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
pbro
Pseudonocardia broussonetiae
Pathway
pbro00860
Porphyrin metabolism
pbro01100
Metabolic pathways
pbro01110
Biosynthesis of secondary metabolites
pbro01120
Microbial metabolism in diverse environments
pbro01240
Biosynthesis of cofactors
Module
pbro_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
pbro_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
pbro00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HOP40_11265
Enzymes [BR:
pbro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HOP40_11265
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HOP40_11265
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QJY46312
UniProt:
A0A6M6JHW7
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All DBs
Position
2276017..2277555
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AA seq
512 aa
AA seq
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MNRAPSTGRVAFVGSGPGDPGLLTVRARDAIASAPLIITDPDVPEAILALVAEGAEVRPA
VGQPADVARDLVAEARAGRTVTRLVSGDPLTVDAVVAEAIAVSGAEVAFDVVPGVPSGTA
VPAYAGVPLGSAHIEADVRAGVDWAKLAVAPGVLVLHAGPTHLAEIASGLTEHGLAAQTP
VAVTASGSQTTQRTVQGTLATLAADASDLEGPLVVTVGDEVGLRAELSWWESRALYGWRV
LVPRTKDQAGAMSDRLAVHGASAEEVPTIAVEPPRSPTQMERAVKGLVDGRYQWVVFTST
NAVRAVWEKFAEFGLDARAFSGVKIACVGTATAEKVRSFGIVPELVPDIEESQESSSEGL
LGIFPPYDDVLDPVDRVLLPRADIATETLAAGLRDRGWEIDDVTAYRTVRAAPPPAPIRE
AIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTIVACIGPQTAETAREFGLRVDVQPDEAR
VPALVDALAAHAARLRAEGALPPPRKAKARRR
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgaaccgagcaccttccaccggacgggtcgccttcgtgggcagcggccccggcgatccc
ggcctgctcaccgtgcgggcgcgggacgcgatcgcgtccgccccgctgatcatcaccgac
ccggacgtgccggaggcgatcctcgccctcgtcgccgagggcgccgaggtgcggccggcc
gtgggccagcccgccgacgtcgcgcgcgacctggtcgccgaggcccgcgccgggcgcacc
gtgacgcggctggtcagcggggacccgctgacggtcgacgccgtggtggccgaggccatc
gcggtgtccggcgccgaggtggcgttcgacgtcgtccccggggtgccctcgggcaccgcg
gtgccggcgtacgcgggcgtgccgctgggctccgcgcacatcgaggccgacgtccgcgcg
ggcgtcgactgggccaagctcgccgtggcgcccggggtcctcgtgctgcacgccggcccg
acgcacctcgcggagatcgcgagcgggctcaccgagcacggcctcgccgcgcagacgccc
gtcgcggtcaccgcgagcgggtcgcagaccacgcagcggaccgtgcagggcacgctggcc
acgctcgcggccgacgcgtcggacctcgagggtccgctcgtcgtcaccgtcggcgacgag
gtcggcctgcgcgcggagctgtcgtggtgggagtcgcgcgcgctctacgggtggcgcgtc
ctcgtgccgcgcaccaaggaccaggccggcgcgatgagcgaccgcctcgccgtgcacggc
gcctccgccgaggaggtcccgacgatcgccgtcgagccgccgcggtcgcccacgcagatg
gagcgggccgtcaagggcctggtcgacggccgctaccagtgggtcgtcttcacctccacc
aacgcggtgcgcgcggtgtgggagaagttcgccgagttcggcctcgacgcccgcgcgttc
tccggcgtcaagatcgcctgcgtcggcacggccaccgcggagaaggtgcgcagcttcggc
atcgtgcccgagctggtgcccgacatcgaggagtcgcaggagtcctcgtccgagggcctg
ctcgggatcttcccgccctacgacgacgtgctcgacccggtcgaccgggtcctgctgccg
cgcgccgacatcgccaccgagaccctcgccgccggtctgcgcgaccgcggctgggagatc
gacgacgtcaccgcgtaccgcaccgtccgggcggcgccgccgcccgcgccgatccgtgag
gcgatcaagaccggcgggttcgacgccgtctgcttcacgagctcgtcgacggtgcgcaac
ctggtcgggatcgcgggcaagccgcacgcccgcaccatcgtggcgtgcatcggcccgcag
acggccgagacggcccgcgagttcggcctgcgggtcgacgtgcagccggacgaggcgcgg
gtgccggccctggtcgacgccctggccgcccacgcggcgcggctgcgggcggagggggcc
ctgccgcccccgcggaaggcgaaggcgcggcggcggtag
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