Puma concolor (puma): 112851426 Help Entry 112851426         CDS       T08890                                  Symbol TGFBR1 Name (RefSeq) TGF-beta receptor type-1   KO K04674   TGF-beta receptor type-1 [EC:2.7.11.30] Organism pcoo  Puma concolor (puma) Pathway pcoo04010   MAPK signaling pathway pcoo04060   Cytokine-cytokine receptor interaction pcoo04068   FoxO signaling pathway pcoo04144   Endocytosis pcoo04218   Cellular senescence pcoo04350   TGF-beta signaling pathway pcoo04371   Apelin signaling pathway pcoo04380   Osteoclast differentiation pcoo04390   Hippo signaling pathway pcoo04520   Adherens junction pcoo04659   Th17 cell differentiation pcoo04926   Relaxin signaling pathway pcoo04933   AGE-RAGE signaling pathway in diabetic complications pcoo05142   Chagas disease pcoo05161   Hepatitis B pcoo05166   Human T-cell leukemia virus 1 infection pcoo05200   Pathways in cancer pcoo05210   Colorectal cancer pcoo05212   Pancreatic cancer pcoo05220   Chronic myeloid leukemia pcoo05225   Hepatocellular carcinoma pcoo05226   Gastric cancer pcoo05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:pcoo00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112851426 (TGFBR1)    04350 TGF-beta signaling pathway     112851426 (TGFBR1)    04390 Hippo signaling pathway     112851426 (TGFBR1)    04371 Apelin signaling pathway     112851426 (TGFBR1)    04068 FoxO signaling pathway     112851426 (TGFBR1)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     112851426 (TGFBR1)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     112851426 (TGFBR1)   09143 Cell growth and death    04218 Cellular senescence     112851426 (TGFBR1)   09144 Cellular community - eukaryotes    04520 Adherens junction     112851426 (TGFBR1)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     112851426 (TGFBR1)   09152 Endocrine system    04926 Relaxin signaling pathway     112851426 (TGFBR1)   09158 Development and regeneration    04380 Osteoclast differentiation     112851426 (TGFBR1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112851426 (TGFBR1)   09162 Cancer: specific types    05210 Colorectal cancer     112851426 (TGFBR1)    05212 Pancreatic cancer     112851426 (TGFBR1)    05225 Hepatocellular carcinoma     112851426 (TGFBR1)    05226 Gastric cancer     112851426 (TGFBR1)    05220 Chronic myeloid leukemia     112851426 (TGFBR1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112851426 (TGFBR1)    05161 Hepatitis B     112851426 (TGFBR1)   09174 Infectious disease: parasitic    05142 Chagas disease     112851426 (TGFBR1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     112851426 (TGFBR1)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     112851426 (TGFBR1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pcoo01001]     112851426 (TGFBR1) Enzymes [BR:pcoo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.30  receptor protein serine/threonine kinase      112851426 (TGFBR1) Protein kinases [BR:pcoo01001]  Receptor serine/threonine kinases (RSTK): TKL group   TGFBR1 family [OT]    112851426 (TGFBR1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH Haspin_kinase FTA2 Motif Other DBs NCBI-GeneID:  112851426 NCBI-ProteinID:  XP_025770751 UniProt:  A0A6P6H5R7 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MQISEVRVWENVHHRMEEAVAAGRYWGLEATGDQALQCFCHLCTKDNFTCVTDGLCFVSV TETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGPFS GKPSSGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEG TTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIF SSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR YTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGL AVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARR CSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMREC WYANGAARLTALRIKKTLSQLSQQEGIKM NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgcagatttcagaagtgagagtgtgggaaaatgtgcatcatagaatggaggaagctgta gctgctggtagatattggggcctggaagcaacaggtgaccaagcattacagtgtttctgc cacctttgtacaaaagacaattttacgtgtgtgacagatgggctctgctttgtctctgtc acagagaccacagacaaagttatacacaatagcatgtgtatagctgaaattgacctaatt ccccgagacaggccgtttgtgtgtgcaccgtcttcaaaaactggctctgtcactacaacg tattgctgcaatcaggaccactgcaataaaatagaactcccgactgttggccctttttca ggaaagccatcatctggccttggtcccgtcgaattggcagctgtcattgctggaccagtc tgcttcgtctgcatctcactcatgttaatggtttatatctgccataatcgtactgtcatt caccatcgagtgccaaacgaagaggatccttccttagatcgtccttttatttcagagggc actacgttgaaagatttaatttatgatatgacaacatcaggctctggatcaggtttacca ttgctcgttcagagaacaattgcaagaactattgtgttacaagaaagtattggcaaaggt cgatttggagaagtttggcggggaaaatggcgaggagaagaagttgctgtcaaaatattc tcctctagagaagaacgctcgtggttccgtgaggccgagatttatcagaccgtaatgtta cgccatgaaaacatcttgggatttatagcggcagacaataaagacaacggtacatggact cagctctggttggtgtcagattatcatgagcatggatccctttttgattatttgaacaga tacacagtgaccgtggaaggaatgataaaactcgctttgtccacagcaagtggacttgcc catcttcacatggagattgttggtacccaagggaaaccagccattgctcatagagatttg aagtccaagaatatcttagtaaagaagaatggaacttgctgcattgcagacttaggactg gcagtaagacacgattcagccacagatacgattgatattgctccaaaccacagagtggga acaaaaaggtacatggcccccgaagttctagatgattccataaacatgaaacactttgaa tccttcaaacgtgctgacatctatgcaatgggcttagtattctgggaaatagctcgacga tgttccattggtggaattcatgaagattaccagctgccttattatgatcttgtaccttct gatccatcagttgaagaaatgagaaaagttgtttgtgaacagaagttaaggccaaatatt ccaaacagatggcagagttgtgaagccttgagagtaatggctaaaattatgagagaatgt tggtatgccaacggagctgctagacttacagctttgaggattaagaaaacattgtcacaa ctcagtcaacaggaaggcatcaagatgtag

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