Puma concolor (puma): 112854256 Help Entry 112854256         CDS       T08890                                  Symbol HKDC1 Name (RefSeq) putative hexokinase HKDC1   KO K00844   hexokinase [EC:2.7.1.1] Organism pcoo  Puma concolor (puma) Pathway pcoo00010   Glycolysis / Gluconeogenesis pcoo00051   Fructose and mannose metabolism pcoo00052   Galactose metabolism pcoo00500   Starch and sucrose metabolism pcoo00520   Amino sugar and nucleotide sugar metabolism pcoo01100   Metabolic pathways pcoo01200   Carbon metabolism pcoo01250   Biosynthesis of nucleotide sugars pcoo04066   HIF-1 signaling pathway pcoo04910   Insulin signaling pathway pcoo04930   Type II diabetes mellitus pcoo04973   Carbohydrate digestion and absorption pcoo05230   Central carbon metabolism in cancer Module pcoo_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate pcoo_M00549   Nucleotide sugar biosynthesis, glucose => UDP-glucose pcoo_M00892   UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc Brite KEGG Orthology (KO) [BR:pcoo00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     112854256 (HKDC1)    00051 Fructose and mannose metabolism     112854256 (HKDC1)    00052 Galactose metabolism     112854256 (HKDC1)    00500 Starch and sucrose metabolism     112854256 (HKDC1)    00520 Amino sugar and nucleotide sugar metabolism     112854256 (HKDC1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     112854256 (HKDC1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     112854256 (HKDC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112854256 (HKDC1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     112854256 (HKDC1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     112854256 (HKDC1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     112854256 (HKDC1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pcoo04131]     112854256 (HKDC1) Enzymes [BR:pcoo01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      112854256 (HKDC1) Membrane trafficking [BR:pcoo04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     112854256 (HKDC1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 VPS13_mid_rpt Motif Other DBs NCBI-GeneID:  112854256 NCBI-ProteinID:  XP_025773496 UniProt:  A0A6P6HDZ9 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MFAVHLMAFYFTKLKEDQIKKVDRFLYHMRLSDETLLDIMARFQAEMQKGLGKDTNPTAS VKMLPTFVRAIPDGSEKGEFLSLDLGGSKFRVLKVQVSEEGKRNVQMESQFYPTPNEIIR GNGSELFEYVADCLADFMKTKGLKHKKLPLGLTFSFPCRQTKLEEGILISWTKKFKARGV QDTDVVDCLAKAIKKHKDIDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL YLGELVRIILLKMAKAGLLFDGKKSSALHTKGKIETRHVAAMEKYKEGLANTREILTDLG LEPSEADCIAVQHICTIVSFRSANLCAAALAAILTRLRENKKLVRLRTTVGMDGTVYKIH PQYPKRLHKVVRKLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT QEQLKAVQGKMRTEFEYGLKRDTHLLATVKMLPTYVCGMPDGTEKGKFLALDLGGTNFRV LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFT FSFPCRQTSIDKGTLIEWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGT MMTCGHEDPNCEIGLIAGTGSNMCYMEEMKNIELVEGDEGKMCINTEWGGFGDNGCIDDI RTQYDEKVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKHGLLFRGQISERLRTRGI FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLYGAGLAAI VEKRREDQGLENLKVTVGVDGTLYKLHPHFSRILQETVKELAPRCDVTLMLSEDGSGKGA ALITAVAKRLQQAQKEK NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgtttgccgtacacttgatggcattttacttcaccaagctgaaggaggatcagatcaag aaggtggacagattcctgtatcacatgcggctctccgatgagacccttttggacatcatg gctcggttccaggctgaaatgcagaagggcctggggaaggacaccaaccccacagcctcc gtgaagatgctgcccacctttgtcagggccattccagatggctcagaaaaaggggagttt ctttccctggatcttggagggtccaagtttcgagtcttgaaggtgcaggtctctgaagag gggaaaagaaacgtccagatggagagtcagttctacccaacacccaatgaaattatccga ggaaacggctcagagctgtttgaatatgtagctgactgtctggcagatttcatgaagacc aaagggttgaagcataagaaattgccccttggcctaaccttttcttttccctgcagacag actaaactggaagagggcatcctgatttcatggaccaagaagtttaaggcacgtggagtt caagacactgatgtggtggattgtctggccaaagctataaaaaaacacaaggacatagac gtggacatcctggccttggtcaatgacaccgtggggaccatgatgacgtgcgcctatgat gatccctactgtgaagttggtgtcatcattggcactggcaccaacgcgtgctacatggag gacatgagcaacattgacctggtggaaggcgacgagggcaggatgtgcatcaacacggag tggggggcctttggggacgacggggctctggaagacatccgcaccgagttcgaccgggag ctggaccttggctctctcaaccctgggaagcagctgtttgagaagatgatcagcggcctg tacctgggtgaacttgtcaggatcatcttgctgaagatggccaaggcaggcctcctgttt gacggcaagaaatcctctgctctccacactaagggcaagattgaaacacggcatgtggct gccatggagaagtataaagaaggcctggccaatacaagagagatcctgacagatctgggc ctggagccttcggaggccgactgcatcgcagttcagcacatctgcaccatcgtgtccttc cgttcagccaatctctgtgcagcggccctggcagccatcctgacacgcctccgggagaac aagaagctggtgcggctccggaccaccgtgggcatggatggcacggtctacaagatacat cctcaatacccaaaacgcctgcacaaggtggtgaggaaactggttccgaactgtgatgtc cgcttcctcttgtcggagagtggaagcaccaagggggctgccatggtgacagcggtggcc tcccgtgtgcaggcccaacggaagcagattgacaaggtgctggctttgttccagctgact caagagcaacttaaggctgtgcagggcaagatgcggactgaattcgagtacgggctgaaa agagacacccacctgctggccacggtcaagatgctgcccacctacgtttgcgggatgccg gatggtacagagaaaggcaagttccttgccctggatctggggggaaccaacttccgggtc ctcctggtaaagatcagaagtgggcggaggtcggtgcgaatgtacaacaagatcttcgcc atccccttggagatcatgcagggcaccggcgaggagctgtttgaccacattgtgcagtgc atcgctgacttcctggactacatgggcctcaagggagcccagctgcccctgggcttcaca ttctcatttccctgcaggcagacgagcattgacaagggaacactcattgagtggaccaaa ggcttcaaggccactgactgtgaaggggaagatgtggtggacatgctcagggaagccatc aagaggagaaatgagtttgacctggacatagttgcgatcgtgaatgacacagtggggacc atgatgacctgtggacatgaagatcctaattgtgagattggcctgattgcaggaacaggc agcaacatgtgctacatggaggaaatgaagaacatcgagctggtggaaggagacgaaggg aagatgtgcattaacaccgagtggggagggtttggagataatggctgcatagatgacatc cggacgcaatatgacgagaaggtggatgaggggtctttgaaccctggcaaacagagatat gagaaaatgaccagcgggatgtacctgggggagattgtgcggcagatcctgattgacctc accaagcacggtctccttttccgtgggcagatttcagagcgtctccggaccaggggcatc tttgaaaccaagttcctgtcccagattgaaagcgatcggctggccctcctccaggtcagg aggatcctgcagcagcttggcctggacagcacgtgtgaggacagcattgtggtgaaggag gtgtgcggagctgtgtcccggcgggcagcccagctctatggcgctggcctggcagccatc gtggagaagaggagggaagaccaggggcttgagaacctgaaggtcaccgtgggtgtggat ggcaccctgtacaagctgcaccctcacttttctcggatattgcaggaaaccgtgaaagaa ctagctcctcgatgtgatgtgacactcatgctgtcagaagatgggagtggaaagggagct gctctgatcactgctgtggccaagaggttacagcaggcacagaaggagaaatag

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