Propithecus coquereli (Coquerel's sifaka): 105811277
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Entry
105811277 CDS
T08746
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq00310
Lysine degradation
pcoq01100
Metabolic pathways
pcoq05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
105811277 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
105811277 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pcoq03036
]
105811277 (DOT1L)
Enzymes [BR:
pcoq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
105811277 (DOT1L)
Chromosome and associated proteins [BR:
pcoq03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
105811277 (DOT1L)
HMT complexes
Dot1-containing complex
105811277 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
105811277
NCBI-ProteinID:
XP_012500887
Ensembl:
ENSPCOG00000021587
LinkDB
All DBs
Position
Unknown
AA seq
1512 aa
AA seq
DB search
MENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHVLQQV
YNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVA
AATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIAN
TSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVV
ELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNAT
TPTKVPESKAAGPTDAPVVSPTLAWPAGAAPTVFRPRPAIAPCVAQDSGAEEDKAGAAPI
KKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTANPERRPKKSQTALDLLHAQTASQTAS
PSPQDAYRSPHSPFYQLPPSVQRPSPNPLLGAPTPPALQKLLESFKIQYLQFLAYTKTPQ
YKANLQQLLDQEKERNTQLLGTAQQLFSHCQEQKEEIRRLFQQKLDELGVKALTYNDLIQ
AQKEISAHNQQLREQSEQLEKDNSQLRSQSLQLLKARCEELKLDWATLSLEKLLKEKQAL
RTQISEKQRHCLELQISIVELEKSQRQQELLQLKSCLPPDDALSTHLRGKGTLGRELEAD
PSRLHLELDCAKFSLPRFSSMSPELSMNGHATSYELCGALSRPSSKQNTPQYLASPLDHE
VVPCTPSHGSRPRLEKLSGLAVPDYTRLSPAKIVLRRHLSQDHAASSRAAASELHPRAEH
AKENGLPYQSPNTSSSLKLSPQDPRPPSPGALQLAGEKSSEKGLKERAYGSSGEAITSLP
ISIPLSTVQPSKLPVSIPLASVVLPSRAERVRSTPSPVPQPRDSASTLEKQIGANAHGAG
SKSLALAPAGFSYAGSVAISGALAGSPAPLAPGAEPSAFEESSGSGSIFAAVGSRSSTPQ
HPPLLAQPRSSHPTSPAHQLSASPRLGGAAQGPLPDASKGDLPSDTGFSDPESEAKRRIV
FTISAGMGSAKQSPSSKHSPLSAGARGDCGQSHGQDSRKRGRRKRASAGTPSLSAGVSPK
RRALPPVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPENSLKSSPIPYQDHDQPPVL
KKERPLGQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGSLAG
RKLTPASEPVNSSKWKSTFSPISDISLAKSADSPLQAGSALSQNSLFTFRPTLEEPVATD
AKLAAHPRKGFPSALAGADGLSPSTNPSHGFAFSGGLAAELNLHSFSDGASLAHKGPEAL
GSPLSFPSQRGKEATEANPFLGKRQLDGLSGLKAEGAKGKEAGESGLALCGPGEKAPPLL
GSKASKGRDRELDLKNGHNLFISAAAVPPGGLLSGPGLAPAASSAGGAAPTAQTHRPFLG
AFAPGPQFTLGPVSLQANLSSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGNF
SSGVTGGTVGGN
NT seq
4539 nt
NT seq
+upstream
nt +downstream
nt
atggagaactacgtgttgatagactatgacaccaaaagcttcgagagcatgcagaggctc
tgtgacaagtacaaccgggccatcgacagtatccaccagctgtggaagggcaccacccag
cccatgaagctgaacacgcggccgtccaacgggctcctgcggcacgtcctgcagcaggtc
tacaaccactcggtgaccgacccagagaagctcaacaactacgagcccttctcgcccgag
gtgtatggggagacgtccttcgacctggtggcccagatgattgacgagatcaagatgacc
gaggacgacctgttcgtggacttggggagcggtgtgggccaggtcgtactccaggttgct
gcagccaccaactgcaagcatcactatggcgtcgagaaagcggacatcccagccaagtac
gcggagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgca
gaatacacattggagagaggcgattttctctcggaagagtggagagagcgcatcgccaac
acgagtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaag
gagcggttcgcaaatatgaaggaaggtggcaggatcgtgtcctcgaagccctttgcacct
ctaaacttcagaataaacagtagaaacttgagtgacatcggcaccatcatgcgcgtcgtg
gagctgtcgcccctgaagggctccgtgtcgtggacggggaagccggtctcctactacttg
cacactattgaccggaccatacttgaaaactatttttctagtttgaaaaatccaaaactc
agggaggaacaagaggcagctcggcgccggcagcagcgggagaataagagcaacgcgact
actcccaccaaggtgcccgagagcaaggcggccggccccacggatgcccccgtggtaagc
cccacgctggcctggccggcaggtgcagctcccacggtattccgccctcgccctgccatc
gccccctgtgttgcgcaggattccggcgctgaggaagacaaagctggagcagcccccatc
aagaagccgtccccctccaaggcccgcaagaagaagctgaacaagaaggggcggaagatg
gccggccgcaagcgcgggcgccccaagaagatgagcactgcaaaccctgagcgaaggccc
aagaagagccaaactgcactggatctcctgcacgcccagaccgcgtcccagacagcgtcc
ccctcgccccaggatgcctacaggtcacctcacagtcccttctaccagctacctccgagc
gtgcagcggccctccccgaacccgctgctgggggcgcccaccccgcccgcgctgcagaag
ctgctagagtccttcaagattcagtacctgcagttcttggcgtacacaaagacccctcag
tataaggccaacctgcagcagctgctggaccaggagaaggagaggaacacacagctgctg
ggcacggcgcagcagctcttcagccactgccaggagcagaaggaggagatcaggaggctc
ttccagcagaaactggacgagctgggagtgaaggccctgacctacaacgacctgatccag
gcgcaaaaggagatctctgcgcacaaccagcagctgcgggagcagtcggagcagctggag
aaggacaacagtcagctgcgcagccagagcctgcagctgctcaaggcccggtgtgaggag
ctgaagctggactgggccacgctgtccctggagaagctgctgaaggagaagcaggccctg
cggacccagatctcggagaagcagcggcactgtctggagctgcagataagcattgtggag
ctggagaagagccagcggcagcaggagctgctgcagctcaagtcctgcctgccgcccgat
gacgccctatccacgcacctgcgcgggaaaggcaccctgggccgcgagttggaggctgac
cccagcaggctgcacctcgagctggactgcgccaaattctcactgccccgcttcagcagc
atgagcccggaactctccatgaacggtcacgccaccagctacgagctctgcggcgccctg
agccggccctcgtccaagcagaacaccccccagtacctggcctcccccctagaccacgag
gtggtgccctgcacgcccagccacggcagccggccacggctggagaagctgtccggcctg
gccgtgcccgactacaccagactctcccctgccaagatcgtgctgcggcggcacctgagc
caggaccacgcagcatccagcagggcggctgccagcgagctgcacccacgagccgagcac
gccaaggagaatggccttccctaccagagccccaacacgtccagcagcctgaagctgagc
cctcaggatccccgtcccccgtcccccggggccttgcagcttgctggggagaagagcagc
gagaagggtctgaaggagcgcgcctacggcagcagcggggaggccatcaccagcctgccc
atcagcatcccgctgagcacggtgcagcccagcaagctgcccgtcagcatcccgctggcc
agcgtggtgctgcccagccgcgcggaaagagtgaggagcaccccgagccctgtgccgcag
ccccgagactccgcatccacacttgaaaagcagatcggtgctaacgcccacggtgctggg
agcaagagcctcgccctggcccctgcaggcttctcctacgccggctcagtggccatcagt
ggggccctggctggcagccctgcgccactggccccaggagccgagccgtccgccttcgaa
gagtcctctggctcggggagcatctttgccgccgtggggtcccgcagctcgacaccacag
cacccgcccctgctggcgcagccccgcagctcccacccaacatctcctgcccaccagctt
tccgccagcccccgactaggtggggctgcccagggccccctccctgatgctagtaagggg
gacctgccctctgacaccggcttctcggatccggagagcgaggccaagcggaggatcgtc
ttcaccatttctgccggcatgggcagcgccaagcagtcgccttccagcaagcacagtcct
ctgagcgcaggtgcccgcggggactgcgggcagagccacgggcaggacagccgcaagcgg
ggccggaggaagcgggcgtcggctgggacccccagcctgagtgcgggcgtgtcccccaag
cgccgggccttgccacctgtggctggcctcttcacgcagccgtcgggatcccccctcaac
ctcaactccatggtcagtaacatcaaccagcccttggagatcacggccatctcgtccccc
gagaactccctgaagagctcccccatcccctaccaggaccatgaccagccccccgtgctc
aaaaaggagcggcccctgggccagaccaacggagcacactactccccactgacctcggac
gaggaacctggctcggaggacgagcctagcagtgcccgaattgagagaaaaattgcaacg
atttccctagaaagcaagtctccccccaaaactttggagaatggtggcagcttggcggga
aggaagctgacgcccgcgagcgagcccgtcaacagcagcaagtggaaatccaccttctct
cccatctccgacatcagcctggccaagtccgcggacagcccgctacaggccggctccgcc
ctgagccagaactccctgttcacgttccggcctaccctggaggagcccgtcgccacggac
gccaagctcgctgctcaccccaggaaaggctttcccagtgccctggcaggggccgatgga
ctcagcccaagcaccaacccctcccatggctttgccttcagcgggggcctggccgcggaa
ctcaacttacacagcttcagcgacggtgcttctctcgcccacaagggccctgaggctctg
ggatccccgctgagcttcccctcgcagcggggcaaggaggccacggaggccaaccccttc
ctcggcaagaggcagctggatggcctgtccggcctgaaggccgagggcgccaaaggcaag
gaggcgggcgagagcggcctggccctgtgcgggcctggggagaaggcgcccccgctgttg
ggcagcaaggccagcaagggccgggaccgggagcttgacctcaagaacggccacaacctc
ttcatctccgcggcagccgtgcctcccgggggtctcctcagcgggcccggcctggccccg
gcggcgtcctctgcaggcggcgcagcccccaccgcccagactcaccggcccttcctgggc
gccttcgccccgggcccacagttcacgctggggcccgtgtccctgcaggccaacctcagc
tcggtggccggctcgtctgtgctgcagtccttgttcagctcagtgccggccgccgcgggc
ctggtccacgtgtcctccgccgccaccagactgaccaactcgcacgccatgggcaacttc
tcctccggggtgacaggcggaacagttggaggtaactag
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integrated database retrieval system
