KEGG   Propithecus coquereli (Coquerel's sifaka): 105824710
Entry
105824710         CDS       T08746                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04010  MAPK signaling pathway
pcoq04015  Rap1 signaling pathway
pcoq04218  Cellular senescence
pcoq04380  Osteoclast differentiation
pcoq04620  Toll-like receptor signaling pathway
pcoq04664  Fc epsilon RI signaling pathway
pcoq04668  TNF signaling pathway
pcoq04750  Inflammatory mediator regulation of TRP channels
pcoq04912  GnRH signaling pathway
pcoq04935  Growth hormone synthesis, secretion and action
pcoq04936  Alcoholic liver disease
pcoq05014  Amyotrophic lateral sclerosis
pcoq05022  Pathways of neurodegeneration - multiple diseases
pcoq05132  Salmonella infection
pcoq05135  Yersinia infection
pcoq05145  Toxoplasmosis
pcoq05161  Hepatitis B
pcoq05163  Human cytomegalovirus infection
pcoq05167  Kaposi sarcoma-associated herpesvirus infection
pcoq05169  Epstein-Barr virus infection
pcoq05170  Human immunodeficiency virus 1 infection
pcoq05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcoq05417  Lipid and atherosclerosis
pcoq05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105824710 (MAP2K6)
   04015 Rap1 signaling pathway
    105824710 (MAP2K6)
   04668 TNF signaling pathway
    105824710 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    105824710 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105824710 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    105824710 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105824710 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    105824710 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105824710 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105824710 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105824710 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105824710 (MAP2K6)
   05161 Hepatitis B
    105824710 (MAP2K6)
   05163 Human cytomegalovirus infection
    105824710 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105824710 (MAP2K6)
   05169 Epstein-Barr virus infection
    105824710 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105824710 (MAP2K6)
   05135 Yersinia infection
    105824710 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105824710 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105824710 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    105824710 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105824710 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    105824710 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105824710 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcoq01001]
    105824710 (MAP2K6)
Enzymes [BR:pcoq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105824710 (MAP2K6)
Protein kinases [BR:pcoq01001]
 Serine/threonine kinases: STE group
  STE7 family
   105824710 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase DUF4344 Choline_kinase APH
Other DBs
NCBI-GeneID: 105824710
NCBI-ProteinID: XP_012517700
Ensembl: ENSPCOG00000025057
UniProt: A0A2K6GHB9
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccgaaagaagcattt
gaacaacctcaaaccagttccacgccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcctataatggaactggga
cgaggtgcgtacggtgtggtggagaagatgcggcatgtacccagtgagcagatcatggca
gtgaagcggatccgggccacggtaaatagccaggagcagaaacggctactgatggattta
gatatttccatgaggacagtggattgtccgtttaccgtcaccttctatggcgcactcttc
cgggagggtgatgtgtggatctgcatggagcttatggacacatcgctagataaattctac
aaacaagtcattgacaaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctttctgtcattcatcgagacgtc
aagccttccaacgtgctcattaatgctctgggccaagtgaagatgtgcgattttggaatc
agtggctacctggtggactctgttgctaaaacaattgatgcaggttgcaaaccatacatg
gccccggaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgaattggccatccttcggtttccctatgattcgtgg
ggaactccatttcagcagctcaaacaggtggtagaagagccatcgccacagctgccagca
gacaagttctctgcagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggcctacgtatccagagcttatgcaacatccatttttcaccctacatgaatccaaa
gcaacagatgtggcatcttttgtaaaactgattcttggagactaa

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