Phascolarctos cinereus (koala): 110216590
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Entry
110216590 CDS
T05867
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00230
Purine metabolism
pcw01100
Metabolic pathways
pcw04927
Cortisol synthesis and secretion
pcw04934
Cushing syndrome
pcw05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110216590 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
110216590 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110216590 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
110216590 (PDE8B)
Enzymes [BR:
pcw01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
110216590 (PDE8B)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PAS_9
PAS
PAS_3
PAS_4
PAS_8
MBR1
Motif
Other DBs
NCBI-GeneID:
110216590
NCBI-ProteinID:
XP_020854098
UniProt:
A0A6P5L7T6
LinkDB
All DBs
Position
Unknown
AA seq
974 aa
AA seq
DB search
MRGCGSGSQAGGAETAAASSCRRAAPGSPSSLQPRTVPGEGISSPALRSALGSPASAGMH
EPGAREGRRYSSKEGTATTLHGLFIKTDAADAIPSVLAYQSRQAGAPSTRRERRELGSGS
SSSAGTASSAPTTCRVRTHYCCSSAEAETQTSYTSVKQVSTAEVRIGPMRLTQDPIQVLL
IFAKEDSQSDGFWWACDRAGYRCNIARTPESAIECFLDKHHEIIVIDHRQDQHFDAEAVC
RSIRATNPSEHTVILAVVSHISGEREETSVLPLLHAGFNRRFMENSSITACYNELIQIEH
GEVRSQFKLRACNSIFTALDHCHEAIEITSDDHVIQYVNPAFERMMGYHKGELIGKELTE
LPKSDQNRADLLDTINTCIKKGKEWQGVYYARRKSGDSVQQHVKITPVIGQGGPSLLRKP
KQRTYCFQPESSRKIRHFVSLKKLCCTADSNKQIHKIHRDSGDKSQTESHSFRYKNRRKE
SIDVKSITSRSSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALD
RVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFSKNMHHSHSHLSL
PITINDVPPCIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFARFGVCEFLNCSEAT
LRAWLQVIEANYHSSNSYHNSTHAADVLHATAFFLGKERVKGSLDHLDEVAALIAATVHD
VDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTAKDNKCNIFKNIDRTHYRTL
RQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEESNSHGEGSDCECNPIGKNFPENQIL
IKRMMIKCADVANPCRPLEMCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPK
SQISFIDYFITDMFDAWDGKEVCVFFFSKKHLVRLRFQLARKELLLPYYNNSTRTQGTQL
IRSFSKNSLSIYVL
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgcgggggtgtgggtccgggtcccaggcgggcggcgcggagactgcagcagcgtcaagc
tgccgccgagctgctccggggagcccgagcagtctgcagcccagaaccgtcccgggggaa
gggatctcctcacccgctctgcgatcagcactgggctctcctgcctctgccgggatgcat
gagccgggcgctcgcgagggacggcggtacagcagcaaagaggggacggcgaccacctta
cacggcctcttcatcaagaccgacgccgccgacgccatcccttcggtgctagcctaccag
agccgccaggccggggccccgagcactcgccgggagcggagggagctggggagcggcagc
agcagcagcgcgggcaccgcatcctctgccccgaccacctgcagggtgcgcacccattac
tgctgcagcagcgccgaggccgagacccagaccagctacaccagcgtcaagcaggtttca
accgcggaagtacgaattgggccgatgagactgacacaggatcctattcaggttttgctg
atttttgcaaaggaagacagtcaaagtgatggattctggtgggcctgtgatagagctggc
tacagatgtaatattgcccgaactccagaatctgccattgagtgctttttagataagcac
catgaaatcattgtaatcgaccacagacaagaccaacactttgatgcagaagccgtctgc
agatcaatccgagctacgaatccatcagaacacacggttatacttgcagttgtttcacat
atatcgggtgaacgtgaagaaacatcagtccttcctcttctccatgcaggcttcaatagg
agatttatggagaatagcagtatcactgcttgttacaatgaactgattcaaatagaacat
ggggaagttcgatcacaattcaaattacgggcatgtaactcaatttttacggcacttgac
cactgtcatgaagccatagaaataaccagcgatgatcatgtcattcagtatgtcaacccc
gccttcgaaaggatgatgggctatcacaagggagagctcataggtaaagaactcactgaa
ctgcccaaaagcgaccaaaaccgtgcagatctgctggataccatcaacacgtgcatcaag
aagggaaaggagtggcaaggggtttactatgccagaagaaaatcaggagacagtgtgcaa
cagcatgtgaagatcacaccagtgattggccaaggagggcccagtctacttagaaaacca
aagcaaagaacctattgtttccaacctgaatcatctaggaaaattagacattttgtgtct
ctcaagaaactgtgttgtacagctgacagcaataaacagatacacaagattcaccgtgat
tcaggagacaagtctcagacagagtctcactcatttagatacaagaacaggaggaaagaa
tctattgatgttaaatcaataacatctcgaagtagtgatgcaccaagtttgcagaatcgt
cgttatccttctatggcgaggatccactccatgaccattgaagctccgatcacaaaggtc
attaatataatcaatgctgcccaagagaatagcccagtaactgtagcagaagccttggac
agagttttggagattttacgaaccacagaactctactctcctcaactgggcactaaagat
gaagatccccacactagtgatctagttggagggctgatgactgatggcttgagaaggtta
tcggggaatgagtacgtgttttctaaaaacatgcaccacagtcacagtcatctttcactg
ccaatcacgatcaatgatgttccaccttgtattgcacaattactcgataatgaagaaagc
tgggacttcaacatctttgaattagaagctgtcacacataaaaggccgttggtttacctg
gggttaaaagtctttgcccgctttggggtctgtgagtttttgaactgttcagaagccact
cttcgggcgtggctgcaggtgattgaggccaactaccactcatcaaactcataccacaac
tctacccatgctgcagatgtcctgcatgcaacggcattcttccttggaaaagagagagtg
aagggaagcctggatcacctggatgaagtggctgccttgatagcagccactgtccacgat
gtggatcaccctggacggaccaactctttcctgtgcaatgcgggcagtgagctagctgta
ctctacaatgacacagctgtcctggagagtcaccacactgccctggctttccagctcaca
gccaaggacaacaaatgcaacattttcaagaacattgacaggacccactatcgaacactg
cgccaggcaatcattgacatggtcttggcgacagagatgacaaagcactttgagcacgtg
aacaagtttgtgaacagtatcaacaagcccatggccgctgaggagagcaactcccacggt
gaaggcagtgactgtgaatgtaaccccattgggaagaacttccctgaaaaccaaatcctg
atcaaacgcatgatgattaaatgtgcagatgtggccaacccgtgccgccctctggagatg
tgcatcgaatgggctggaaggatctcagaagagtattttgcacagacggatgaagagaag
agacaagggctaccagtggtgatgccagtatttgatcgaaatacttgcagcatcccaaag
tcccagatctccttcattgactatttcataacagatatgtttgatgcttgggatggtaag
gaagtttgtgttttctttttctccaagaaacacctggttagattgagatttcaattagcc
agaaaggaattgttattgccttactataataacagtacaagaacacaaggaacccagctc
attcgttcattcagcaaaaattcactaagcatatatgtgttgtag
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