KEGG   Phyllostomus discolor (pale spear-nosed bat): 114492341
Entry
114492341         CDS       T07739                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04010  MAPK signaling pathway
pdic04020  Calcium signaling pathway
pdic04022  cGMP-PKG signaling pathway
pdic04114  Oocyte meiosis
pdic04218  Cellular senescence
pdic04310  Wnt signaling pathway
pdic04360  Axon guidance
pdic04370  VEGF signaling pathway
pdic04380  Osteoclast differentiation
pdic04625  C-type lectin receptor signaling pathway
pdic04650  Natural killer cell mediated cytotoxicity
pdic04658  Th1 and Th2 cell differentiation
pdic04659  Th17 cell differentiation
pdic04660  T cell receptor signaling pathway
pdic04662  B cell receptor signaling pathway
pdic04720  Long-term potentiation
pdic04724  Glutamatergic synapse
pdic04728  Dopaminergic synapse
pdic04921  Oxytocin signaling pathway
pdic04922  Glucagon signaling pathway
pdic04924  Renin secretion
pdic05010  Alzheimer disease
pdic05014  Amyotrophic lateral sclerosis
pdic05020  Prion disease
pdic05022  Pathways of neurodegeneration - multiple diseases
pdic05031  Amphetamine addiction
pdic05152  Tuberculosis
pdic05163  Human cytomegalovirus infection
pdic05166  Human T-cell leukemia virus 1 infection
pdic05167  Kaposi sarcoma-associated herpesvirus infection
pdic05170  Human immunodeficiency virus 1 infection
pdic05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pdic05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114492341 (PPP3CA)
   04310 Wnt signaling pathway
    114492341 (PPP3CA)
   04370 VEGF signaling pathway
    114492341 (PPP3CA)
   04020 Calcium signaling pathway
    114492341 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    114492341 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    114492341 (PPP3CA)
   04218 Cellular senescence
    114492341 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    114492341 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    114492341 (PPP3CA)
   04660 T cell receptor signaling pathway
    114492341 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    114492341 (PPP3CA)
   04659 Th17 cell differentiation
    114492341 (PPP3CA)
   04662 B cell receptor signaling pathway
    114492341 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    114492341 (PPP3CA)
   04921 Oxytocin signaling pathway
    114492341 (PPP3CA)
   04924 Renin secretion
    114492341 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    114492341 (PPP3CA)
   04728 Dopaminergic synapse
    114492341 (PPP3CA)
   04720 Long-term potentiation
    114492341 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    114492341 (PPP3CA)
   04380 Osteoclast differentiation
    114492341 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    114492341 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114492341 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    114492341 (PPP3CA)
   05163 Human cytomegalovirus infection
    114492341 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114492341 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    114492341 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114492341 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    114492341 (PPP3CA)
   05020 Prion disease
    114492341 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    114492341 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    114492341 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114492341 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pdic01009]
    114492341 (PPP3CA)
Enzymes [BR:pdic01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     114492341 (PPP3CA)
Protein phosphatases and associated proteins [BR:pdic01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     114492341 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 114492341
NCBI-ProteinID: XP_028362379
EnsemblRapid: ENSPDIG00005004381
UniProt: A0A6J2L657
LinkDB
Position
1:88571106..88883945
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgatcccaagttgtcgacgaccgacagggtggtaaaagct
gtcccatttcctccaagtcaccggcttacagcaaaagaagtatttgataatgatgggaaa
cctcgagtggatatcttaaaggcacatctcatgaaggagggcaggttggaagagagtgtt
gcattgagaataataacagagggggcttcaattctccgacaggaaaaaaatttgctggat
atcgatgcaccagtcactgtttgtggggacatccatggacaattctttgacttgatgaag
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtatcgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttactccgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaatcaagtattcagaacgtgtctatgacgcctgtatggac
gcctttgactgcctgcctctggccgccctgatgaaccagcagttcctgtgtgtgcatggt
ggtctgtccccagagattaacactttagatgacatcagaaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgcgacatcctgtggtcagaccccctggaagactttggc
aatgagaagactcaggaacacttcactcacaacacagtcaggggatgttcgtacttctac
agttaccccgctgtttgtgaattcttacagcacaataacttgttatctatactccgagcc
catgaagcccaggatgcagggtatcgcatgtacaggaagagccaaacaacaggcttccct
tctctaattacgattttctccgcaccaaattacttagatgtgtacaataacaaagctgca
gtattaaagtatgagaacaacgtcatgaatatcaggcagttcaactgttctcctcatcca
tactggcttccaaatttcatggatgtgttcacttggtctttgccatttgttggggagaaa
gtgactgagatgctggtaaatgttcttaacatctgctcagatgatgaactggggtcagaa
gaagatggatttgatggagccacagctgcagcccggaaggaggtgataaggaacaagatc
cgagcaataggcaaaatggccagagtgttctccgttctcagagaagagagtgagagtgtg
ctgacgctgaaaggcctgacgcccaccggcatgctccccagcggagtgctctctggaggg
aagcagaccctgcaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcaccagcttcgaggaggccaagggcttagaccgaattaac
gagaggatgccgcctcgcagagacgccatgccctctgatgccaacctcaactccatcaac
aaggctctcgcctcagagactaacggcacagacagcaatggcagcaatagcagcaatatt
cagtga

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