Phyllostomus discolor (pale spear-nosed bat): 114502661
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Entry
114502661 CDS
T07739
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic00310
Lysine degradation
pdic01100
Metabolic pathways
pdic05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
114502661 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
114502661 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pdic03036
]
114502661 (DOT1L)
Enzymes [BR:
pdic01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
114502661 (DOT1L)
Chromosome and associated proteins [BR:
pdic03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
114502661 (DOT1L)
HMT complexes
Dot1-containing complex
114502661 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
114502661
NCBI-ProteinID:
XP_028375554
EnsemblRapid:
ENSPDIG00005016330
UniProt:
A0A6J2M8B1
LinkDB
All DBs
Position
8:38115513..38174520
Genome browser
AA seq
1732 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTAAPSPQDAYKSPQSPFYQLPPSVQRQPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDSTSLHLRGKGGLGRELEAEPGRLHLELDCSKFSLPHFSSMSPELSMNGHVAGY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASVKASAGELHPRAEHTKENGLPYQSPGLTNGIKLSPQDPQPSSPMALQM
TGEKGSEKGLKERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESSSTLEKQMGANGHGAGSNAAGSKGLALAPTAGFSYTGSVAISGALAGSPA
PLAAGAEPSAFDESSSSGSLFTTMSSRSSTPQHHQLLVQPRNSGPASPTHQLCVSPRLSA
AQGPLPDSSKGDLPPEAGFSDPENEAKRRIIFTISAGAGSAKQSPSNKHSPLPGGARGDS
SQSHGQDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNIN
QPLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEQ
GSTRIERKIATISLESKSPPKTLENGGSLIGRKPVPSSEPINSSKWKSTFSPIADLSLAK
AADSPLQASSALSQNSLFAFRPALEELGSVDAKLAAHPRKSFPGALSGAGGLSPVSNPPN
GFAFSGGLAADLSLHSFSDGASLPHKAPEAASLGAPLSFSAPRGKEGSTEPGTFVNKRQL
DVLGGPKGEGVKGREAEGGLPMCTPSDKASSHGKVGKGRDREPDFKNGHNLFISAAAVPT
GGLLSGPGLTTAVSSAGGTAPSSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFS
SVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHAVPSSSTHPFGTSFGSGA
ACRSTTLSLTPMQAVASTPASSFQALSSVETRQPPPQPPLPMSRPPAGPPAHHEPPPPNV
ALPPTPVMLPANSEPVVLQKLAPLPSNQAFLPASSAASLPPANASLSIKLASLPHKVSRP
SFMVHHQSLPGLALAQASPMIPQASSTGPSAMWVSLGMPPPYAARLAGVKPR
NT seq
5199 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccatgatgctgctcatgaaatcattgagacc
atccgatgggtctgtgaggaaatcccagacctcaagcttgctatggagaattatgtccta
attgactatgacaccaaaagctttgaaagcatgcagaggctctgtgacaagtacaaccgg
gccattgacagcatccaccagttgtggaagggaaccacacagcctatgaagctgaacacg
cggccatccaacgggctcctgcggcacatcctgcagcaggtttacaaccactcagtgacg
gaccctgagaagctcaacaactacgagcccttctccccagaggtgtatggggagacctcc
ttcgacctggtcgcgcagatgattgacgaaatcaagatgacagaggatgacctatttgtg
gacctgggaagtggagtgggccaggtcgtgctgcaggtcgcggcagccaccaactgcaaa
catcactacggagtcgagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgatttcctctcggaggagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaatatg
aaggaaggtggcagaattgtgtcctcgaagccctttgctcctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactacttttctagtttgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgagaaaataagagtaatacaaccacccccacgaaggtgccc
gagagcaaggcagctgtgcctgcagacacctctgtggattctggtgctgaggaagagaaa
gcagcgacaaccgctatcaagaagccgtccccttccaaagcacggaagaagaaactgaac
aagaagggacggaagctggctggccggaagcgtggacgtccgaagaagatgagcactgcg
aaccccgagcgtaagcccaagaagaaccctactgcactggacctgctgcacgcccagact
gtgtcccagacggccgcaccctcaccgcaggatgcgtacaagtcacctcaaagtccgttt
tatcagctacctcccagcgtgcagcggcagccccctgaccaactgctgctggcacccacc
ccacccgcactgcagaagctgctagagtccttcaagatccagtacctgcagttcctagca
tacacgaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaatgcccggttgctgggggccgcacagcagctatttggccactgtcaagcccagaaa
gaagaaataaagagactcttccagcagaaactggatgagttgggagtgaaggctctgacc
tacagtgacctgatccaagcgcagaaggagatctcagctcacaaccagcagctccgagag
cagacagagcagctggagaaggacaacagggagctaaggagccagagcctgcagctgctg
aaggctcggtgtgaggaactgaagctggactggtccacactgtcgctggaaaacctgctg
aaggagaagcaggccctgaagagccagatctctgaaaaacagaggcactgtctagagctg
cagataagcattgtggagctggaaaagagccagcggcagcaggaactcctacagctcaag
tcctgcgtgccaccagacgactccacgtctttgcacctgcgagggaaaggtggcctgggc
cgggaactggaggcggagcctggtcggctgcaccttgagctagactgctctaagttctca
ctgccccacttcagtagcatgagcccagagctctccatgaatggccacgtggccggctat
gagctctgcaacacgctgagccggccctcatccaaacagaacaccccccagtacttggcc
tccccactggaccaggaggttgtgccctgtacccccagccatagcagccggccccggctt
gagaaactgtctggcttggccttgccagactacaccaggctctccccagccaagctggtg
ctgagacgccacctaagtcaggaccacacagccagtgtcaaggcatctgctggcgagctg
catccacgagctgagcacaccaaggagaatggccttccgtaccagagtccaggcctcacc
aacggcatcaagctgagccctcaggatccacagccctcatcccccatggccttacagatg
acaggagaaaagggcagtgagaagggtctgaaggagcgcacctacgccagcagcggtgag
gccatcaccagcctacctgtcagcatcccactcagtactgtgcagcccagcaagctgccc
gtcagcatccccctggccagcgtggtattgcccagccgcgccgagaaggtgagaagcacc
cccagccctgtgcctcagacccgagagtcctcatccacacttgaaaagcagatgggtgct
aatggccatggtgctgggagcaacgctgctggaagcaaaggcctcgccctggcccccaca
gcaggtttctcctacactggctcagtggccatcagtggggccctggcaggcagcccagcc
ccgcttgctgctggagctgagccctctgccttcgatgagtcctccagttcggggagcctc
ttcactaccatgagctcccgcagctccaccccacagcaccatcaactactagtgcagccc
cggaactccggtccggcctcaccgactcaccagctctgtgttagcccccggctgagtgct
gcccagggcccactccctgattccagcaaaggagaccttccccctgaggctggcttctca
gatccagagaacgaggccaagaggaggatcatcttcaccatctcagctggtgctggcagc
gccaagcagtcgccttctaacaagcacagccctctgccagggggcgcccgcggagacagc
agccagagccatggacaggacagccgaaagcggggcaggaggaagcgggcatcagcaggg
actcctagcctgagctcgggtgtgtcccccaagcgccgggccttgccatctgtcgccggt
ctcttcacacagtcttcagggtcccccctcaacctgaactccatggtcaacaacattaac
cagcctttggaaatcacagccatctcgtcccctgagagctccctgaagagctcccctgtc
ccttaccaggacaatgaccagccgcccgtgctcaagaaggagaagcccctgagccaaacc
aatggggcccactactccccactgacctccgacgaggagccgggctctgaggacgagcaa
ggcagcaccagaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccg
aaaaccttagaaaatggtggcagtctgataggaaggaagccggtgccctccagcgagccc
atcaacagcagcaagtggaagtccaccttctcgcccatcgccgacctcagcctggccaag
gctgccgacagcccactacaggccagctccgctctgagccagaactccctgttcgctttc
cggcccgccctagaggagcttggctcagttgatgccaagctggccgcccaccccaggaag
agcttcccgggtgcactgtcaggggctggcgggctgagtcccgtcagcaaccctcccaac
ggctttgccttcagcgggggcctggctgccgacctcagtttacacagcttcagtgatggt
gcttctctcccccacaaggcccctgaggcggccagcctgggtgcccccctgagcttttcc
gcccctagaggcaaggagggcagcacagagcctggcacctttgtgaacaagaggcagctg
gatgtattgggtggcccaaaaggcgagggggtcaagggcagggaggcagaggggggcctg
cccatgtgcacaccctcagacaaggcctcgtcgcatggcaaggtgggcaagggccgggac
cgtgagcctgacttcaagaatggccacaatctcttcatttccgcggctgccgtgcctact
gggggtctcctcagcggtccaggcctcaccacagcagtgtcctcagcaggcggcacagcc
ccctcctcccagacacaccggcccttcctgggcactttcgcacctggcccacagtttgcc
ttgggccccatgtccctgcaggccaacctaggctcgtctgtgctgcagtccttgttcagc
tctgtgccggctgccgctggcctagtgcacgtctcatcagctgcaacaagactgaccaac
tcgcatgccatgggcagcttttcctctggtgtggcaggcggtgcagttggaggtatcttt
aaccacgcggtgccttcctcctccactcatccgtttggaaccagtttcggcagcggggct
gcttgtcgcagcaccacgctgagcttaacccccatgcaggcggtggccagtacccccgcc
tcttcctttcaggccctgtcctctgtggagacgaggcagcccccaccccagcctcctctg
cccatgagtcgtccccctgcggggccaccagcacaccacgagcccccccctcctaacgtc
gccttgcctcctactcccgtgatgctccctgctaactctgagcccgtggtcctacagaaa
cttgcgcccctcccgtctaaccaagctttcttacctgcttcctctgctgcttctctgcct
cctgctaacgcctctctgtccatcaagctcgcctccctcccacacaaggtctcccgcccc
tcttttatggtgcaccaccagtccctgccagggctggccctggcccaggcctcgcccatg
atcccgcaggccagctccacggggccatccgccatgtgggtttcccttggcatgccgcct
ccttatgccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
