Pyrococcus furiosus COM1: PFC_10210
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Entry
PFC_10210 CDS
T02183
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
pfi
Pyrococcus furiosus COM1
Pathway
pfi00290
Valine, leucine and isoleucine biosynthesis
pfi00660
C5-Branched dibasic acid metabolism
pfi01100
Metabolic pathways
pfi01110
Biosynthesis of secondary metabolites
pfi01210
2-Oxocarboxylic acid metabolism
pfi01230
Biosynthesis of amino acids
Module
pfi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pfi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PFC_10210
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PFC_10210
Enzymes [BR:
pfi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
PFC_10210
4.2.1.35 (R)-2-methylmalate dehydratase
PFC_10210
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Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AFN04961
UniProt:
I6USF4
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All DBs
Position
complement(1842009..1843151)
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AA seq
380 aa
AA seq
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MTLIEEILGGKSGESVVRRVDLVYAHDGTMPLIIEAFNKVFATVRARAYIFFDHVYPAPT
VKIANLQKEIRDFAKRHRIPVIEGQGISHQLVVEMGLTENSKIVVGADSHTPTLGALGVF
AVGMGATDVAVILGLGKTWFRIPESVGVILEGNPSRYVMATDVILHLLSLLKDYDMNYRA
VEFFNVPFSLDERLTLTNFVVEANAKTGIIGEEYTGDGYVKELEIELNSLNPLVAKPHNP
ANVVPVEEVEGTKIDQVFIGSCTNGRFEQISKAAEILEGEKVAVRTIVGPASMNVYKRMI
EEGVARKLIEAGAVILPPGCGPCLGRHMGVVGDGEIVLSTTNRNFRGRMGSPNAQIYLSN
PITAAVSALYGEITNPEGAI
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgacattaattgaagaaattctcggtggaaaatctggagaaagtgttgttagaagagtg
gatttagtatacgctcatgatgggacaatgcccttaataatagaggcattcaacaaggtc
tttgccactgtaagagcaagagcatatatcttctttgaccacgtgtatccagcgcctaca
gtaaagattgcaaacttgcaaaaagagattagagatttcgcaaaaaggcatagaattcca
gtaatagaaggtcaaggaattagccatcaactcgtcgttgaaatgggattaacagaaaac
tcaaagatagttgtgggagcagattcccatactccaactctcggagcacttggagttttt
gcagtagggatgggagcaacggatgttgctgtaatcttagggctaggaaagacatggttt
agaattccagagagcgttggagtaatcctagagggcaatccttcaagatacgttatggca
actgatgtgatacttcatctcctctcactactaaaagactacgacatgaactacagggcc
gtagaattcttcaacgttcctttttcccttgatgagcgtctaacgctaacgaactttgta
gtggaagctaatgcaaaaacgggaataataggggaagagtacacaggagatgggtatgta
aaagagctggagattgaattaaattctctcaatccccttgttgcaaagccgcataatcca
gcaaacgttgttccagtggaagaagtagagggaacaaagatagatcaggttttcataggc
tcgtgcacaaatgggaggtttgaacaaatttccaaagctgccgagattttagagggagag
aaagtagcagttagaaccatcgtaggtcctgcctctatgaatgtatacaagagaatgata
gaggagggagtagcaagaaaactcattgaagctggagcagttattcttcccccaggatgc
gggccttgcttagggaggcatatgggcgtagttggagatggggagatagtcctaagcaca
acaaacaggaacttcagaggaagaatgggatctcccaatgcccaaatttacctttctaat
ccaataactgcagctgtaagcgccttgtatggagagataacgaacccggagggagctata
tga
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