Pseudomonas frederiksbergensis: PFAS1_21345
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Entry
PFAS1_21345 CDS
T04786
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
pfk
Pseudomonas frederiksbergensis
Pathway
pfk00790
Folate biosynthesis
pfk01100
Metabolic pathways
pfk01240
Biosynthesis of cofactors
Module
pfk_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pfk00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
PFAS1_21345
Enzymes [BR:
pfk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
PFAS1_21345
6.3.2.17 tetrahydrofolate synthase
PFAS1_21345
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
APV41771
UniProt:
A0A1P8EZX2
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All DBs
Position
4602086..4603393
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AA seq
435 aa
AA seq
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MIERTLGEWLAYLEQLHPSAIDMGLERSQQVASRMGLGKPAPRVITVTGTNGKGSTCAFV
ASLLRAQGLNVGVYNSPHLLRYNERVQVNGVEATDAELCEAFAAVEAGRGDTSLTYFEMG
TLAAFWLFQHASLDAVVLEVGLGGRLDTVNVVDADMALVTSIGVDHADYLGDTRESVAFE
KAGIFRQSAPALCGDLNPPQPLLDKARELNCPFFLRGRDFDLGITDHNWQWRGLDAQGRA
VELHDLPLLDLPMENAALALQAYLLLGLPWVDAQIIAALKATRVVGRLDRRQFDWQGKRL
NLLLDVGHNPHAAEYLARRLASRPPAGKRLAVFGLLADKDLDGVVGELSASVQHWAVAPL
DSPRARPVADLHAALHNLGASVTSYDSVAAALEGQCALATSDDEILLFGSFYCVAEALEW
LSRRSTEEAANGIAG
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgatcgaacgtacccttggcgagtggctcgcctaccttgagcagttgcacccttcggcc
atcgacatgggcctggagcgctcgcagcaggtagcgtcccgcatgggactgggcaagccg
gcgcctcgggtgatcacggtcaccggcaccaacggcaaaggttctacctgcgcattcgtg
gcttcgttgctgcgggcgcagggcctgaacgtaggtgtctacaattctccgcacctgctg
cgttataacgagcgggtgcaggtcaatggcgtcgaagccactgacgccgagctgtgcgaa
gcctttgctgcggtcgaggcgggtcgtggcgatacttcgctgacgtacttcgaaatgggc
accttggcggcgttctggctgtttcaacacgccagtctcgatgcggtggtgctggaagtc
gggttgggcgggcgtctggacacggtcaatgtggtcgacgccgatatggcgctggtcacc
agcattggtgtcgatcacgcggactatctgggcgatacccgagaatccgtcgcgttcgaa
aaggccggcatcttccgccagagcgcgcctgcgctgtgtggcgacctgaatcctccacaa
cccctgctggataaagcgcgcgagctcaattgcccgtttttcctgcgtgggcgcgatttc
gacctcggtatcaccgatcacaactggcaatggcgcggtcttgacgctcaagggcgtgct
gtcgagctgcatgatctgccgttgctcgatctgccgatggaaaacgccgcgctggcgttg
caggcttacctgttgctcgggttgccgtgggtggatgcgcaaattattgctgcgctgaaa
gccactcgggtggtcggtcgcctcgatcgccgtcaattcgactggcagggcaagcgtctg
aatttgttgctggacgtggggcataacccccatgcggcagagtatctggctcgtcgcctg
gccagccgtccaccggccggcaagcgtttggcagtgttcggactgttggcagacaaggat
ctggatggtgtcgtcggtgaattgagtgctagtgtccagcactgggccgtcgcgccgctg
gattcgccacgagcacgcccggttgccgatttgcacgcagcgttgcataaccttggcgcc
tcggtaacatcttatgacagcgtggccgccgccctggaagggcagtgcgcgctggcgacg
agcgacgacgagattctgttgttcggatcattttattgtgtcgccgaggccctagaatgg
ctgtcccggcgctccacggaggaagcggcaaatggcattgctggataa
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