Phytohabitans flavus: Pflav_065460
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Entry
Pflav_065460 CDS
T06516
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
pfla
Phytohabitans flavus
Pathway
pfla00860
Porphyrin metabolism
pfla01100
Metabolic pathways
pfla01110
Biosynthesis of secondary metabolites
pfla01120
Microbial metabolism in diverse environments
pfla01240
Biosynthesis of cofactors
Module
pfla_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
pfla_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
pfla00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Pflav_065460 (hemD)
Enzymes [BR:
pfla01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Pflav_065460 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Pflav_065460 (hemD)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BCB80136
UniProt:
A0A6F8Y206
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All DBs
Position
complement(7051880..7053460)
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AA seq
526 aa
AA seq
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MSRTRKPAGRIAFVGAGPGDPGLLTRRAHAALTEADQVVYDRGVSEPLLDAIRAEAKSDT
QFSPAEGAPGDVAKVLISAARSGLQAVHLVAGDPFGHDSVVKEVQAVARTAVHFEVVPGV
GQAEGVSTYAGVPLPGVRTAADVDDVSALDFEALAAAITRGSLALAVDAGDLAAVRDGLL
AVGVDGETAVGVTGDGTGETQYTTSSTVDSFVAAALGFTGRVVLTLGQGVAHRDKLSWWE
NRPLYGWKVLVPRTKEQAGLMSEALRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVDGR
YAWVIFTSVNAVRAVWEKFGEHGLDARHFGGVKIACIGEATADAVRAFGIQPELIPAGEQ
SSEGLLAEFSPHDEVLDPVGRVLLPRADIATETLAAGLSERGWEVDDVTAYRTVRAAPPP
AEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHTRTVVAVIGPKTAETATEFGLRVDVQ
PPHASVPDLVEALAGYAVELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atgagccgcacccgtaagcccgcaggccggattgccttcgtcggggccggtcccggcgat
cctggcctgctgacccgccgggcgcacgccgcgcttacggaggccgaccaggtcgtctac
gaccggggcgtctccgagccgctgctcgacgcgatccgtgcggaagccaagagcgacacc
cagttcagcccggccgagggggcaccgggcgacgtggccaaggtcctgatctccgcggcc
cgttccggcctccaggcggtacaccttgtcgcgggcgacccgttcggccacgactccgtg
gtcaaggaggtgcaggcggtcgcgcgtaccgccgtgcacttcgaggtggtgcccggcgtc
ggccaggccgagggcgtctccacctacgccggcgtgccgctgcccggcgtgcgcacggcc
gccgacgtcgacgacgtgtccgcgttggacttcgaggcactcgccgcggcgatcacccgt
ggctcgctcgcgctcgcggtcgacgcgggcgacctcgccgccgtacgtgacggcctgctc
gccgtcggggtggatggcgagacggccgtgggcgtgaccggcgacggcaccggcgagacg
cagtacacgacgtcgtccaccgtggacagcttcgtggccgccgcgctcggcttcaccggc
cgcgtcgtgctcacgctgggccagggcgtcgcccaccgcgacaagctgagctggtgggaa
aaccgcccgttgtacgggtggaaggtgctcgtgccccgtaccaaggagcaggccggcctg
atgagcgaggcgctgcgggcgtatggggcgatcccgtgcgaggtgccgaccatcgcggtc
gagccgccgcggacgccggcccagatggagcgggcggtcaaggggcttgtcgacggccgg
tacgcgtgggtcatcttcacctccgtcaacgcggtgcgtgcggtctgggagaagttcggt
gagcacggcctcgacgcccgccacttcggcggcgtgaagatcgcctgcatcggcgaggcg
acggccgacgcggttcgtgcgttcggcatccagcccgagctaatcccggcgggcgagcag
tcgagcgagggcctgctggctgagttctcgccgcacgacgaggtgctcgacccggtcggc
cgcgtgctgctgccgcgcgccgacatcgcgaccgagacgctcgcggccggcctgagcgag
cgcggatgggaggtcgacgacgtcaccgcgtaccgcacggtgcgcgccgcgccgccaccc
gccgagatccgggacgccatcaaatcgggcggcttcgatgcggttctcttcacgtcgtcc
tccacggtgcgtaacctggtgggtatcgccggtaagccacacacccgcacagtggtcgcc
gtgatcggcccgaagacggccgagacggcgacggagtttggcctccgggtcgacgtccag
cccccacacgcgtccgtcccagaccttgtcgaggccctcgccgggtatgccgtggagctg
cgcgagaagctggccgccatgccggccaagcagcgccgtggttcgaaggtgcaggggccc
accgcccttaggttccggtga
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