Pteropus giganteus (Indian flying fox): 120594235
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Entry
120594235 CDS
T07511
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pgig
Pteropus giganteus (Indian flying fox)
Pathway
pgig00010
Glycolysis / Gluconeogenesis
pgig00020
Citrate cycle (TCA cycle)
pgig00620
Pyruvate metabolism
pgig00785
Lipoic acid metabolism
pgig01100
Metabolic pathways
pgig01200
Carbon metabolism
pgig01210
2-Oxocarboxylic acid metabolism
pgig04066
HIF-1 signaling pathway
pgig04922
Glucagon signaling pathway
pgig05230
Central carbon metabolism in cancer
pgig05415
Diabetic cardiomyopathy
Module
pgig_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
120594235 (PDHA1)
00020 Citrate cycle (TCA cycle)
120594235 (PDHA1)
00620 Pyruvate metabolism
120594235 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
120594235 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
120594235 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
120594235 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
120594235 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
120594235 (PDHA1)
Enzymes [BR:
pgig01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
120594235 (PDHA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
120594235
NCBI-ProteinID:
XP_039708166
LinkDB
All DBs
Position
Unknown
AA seq
440 aa
AA seq
DB search
MTSLRHCHVALWLRRAVRSRPVKETWRHLGRAVCVGGSRRRCSCSYCPQSMRKMLAAVSR
VLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRTMQT
VRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLS
VREILTELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVC
LTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIP
GLRVDGMDVLCVREATKFAAAHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEV
RSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATSDPEPPLEELGYHIYS
NDPPFEVRGANQWIKFKSVS
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgacgtctctccgtcactgtcacgtagcgctgtggttaaggcgtgccgtccgctcccgg
ccggtgaaggagacttggagacatctgggtcgcgcggtttgtgtcggtggtagtcgccgc
cgctgcagctgttcttactgccctcagtccatgaggaagatgctcgccgccgtctcccgc
gtgttgtcgggcgccgcccagaagccggcaagcagagtgctggtggcatcccgtaatttt
gcaaacgatgctacatttgaaattaagaagtgtgatctccaccggctggaagagggccct
cctgtcacaacagtgctcaccagagaggatgggctcaaatactacaggacgatgcagact
gttcgccgaatggagttaaaggcagatcagctgtataaacagaaaatcattcgtggtttc
tgtcacttgtgtgacggtcaagaagcttgttgtgtgggcctggaggctggcataaatccc
acagatcatctgatcacagcctatcgagctcatggctttacctttactcgtgggctttct
gtccgagaaattctcacagagcttacagggcgaagaggaggttgtgctaaaggcaaaggt
ggatcaatgcatatgtatgccaagaacttctacggaggcaatggcatcgttggagctcag
gtgcccctgggagctgggattgctctggcctgtaagtataatggaaaagatgaagtctgt
ttgactttatatggcgatggtgctgctaatcagggtcagatattcgaagcttacaatatg
gcagccttgtggaaattaccttgtattttcatctgtgaaaataaccgctatgggatggga
acatctgttgagagagcagcagccagcactgattactacaagagaggtgacttcattcct
gggctgagggtggatggaatggatgtcctgtgtgtccgggaggcgacgaagtttgcagct
gcccattgtagatctggaaaggggcccatactgatggagctgcagacttaccgttaccat
ggacacagcatgagtgatcctggagtcagttatcgtacacgagaagaaattcaggaagta
agaagtaagagcgaccctatcatgctcctcaaggatagaatggtgaacaacaatcttgcc
agtgtcgaagaattaaaggaaattgacgttgaagtgaggaaagaaatcgaagatgccgcc
cagtttgccacatctgatcctgaaccacctttggaagaactaggctatcacatctactcc
aacgatccaccttttgaagttcggggtgcaaatcagtggatcaagtttaagtccgtcagt
taa
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