Pteropus giganteus (Indian flying fox): 120599267
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Entry
120599267 CDS
T07511
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pgig
Pteropus giganteus (Indian flying fox)
Pathway
pgig00230
Purine metabolism
pgig01100
Metabolic pathways
pgig04927
Cortisol synthesis and secretion
pgig04934
Cushing syndrome
pgig05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
120599267 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
120599267 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
120599267 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
120599267 (PDE8A)
Enzymes [BR:
pgig01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
120599267 (PDE8A)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PAS
PAS_9
PAS_4
PAS_3
PAS_8
DUF5894
MiaE
Response_reg
Sina_ZnF
Motif
Other DBs
NCBI-GeneID:
120599267
NCBI-ProteinID:
XP_039714167
LinkDB
All DBs
Position
Unknown
AA seq
757 aa
AA seq
DB search
MKFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLAKHHDIIIIDH
RNPRQLDAEALCRSIRSSKFSENTVIIGVVRRPDREESSVMPLIAAGFTRRYVENPSLMA
CYNELLQLEFGEVRSQLKLRTCNSIFAALEKSQEAVEITSEDHVIQYANPAFETTMGYES
GELIGKKLAEVPINEKKADLLDTINSYIRMGKEWQGICYAKNGDNVQQNVKIIPVIGQGG
RIRHYVSIIRVCSGNNKAEKIAECVQSDRLTDNQSGKHKDKRKSSLDVRAVGHRASEVAS
QRRHSSMARIHSMTIEAPITKVINIINAAQENSPMPVTEALDRVLEILRTTELYSPQFGA
KDDDPHASDLVGGLMSDGLRRLSGNEYALSTKNFQQIASNIVTPISLHDVPPRIAQAIEN
EDYWDFDIFELEAATQNRPLIYLGLKIFARFGICELLNCSEATLRTWFQLIEANYHSSNP
YHNSTHSADVLHATAYFLCRERIKQTLDPVDEAAALIAATIHDVDHPGRTNSFLCNAGSE
LAILYNDTAVLESHHAALAFQLTIRDDKCNIFKNMERNDYRTLRQAIIDMVLATEMTKHF
EHVNKFVNSVNKPLAALEANEETDEEQAAINTVLRTPENRTLIKRMLIKCADVSNPCRPL
EQSIEWAARISEEYFSQTDEEKRQDLPVVMPVFDRNTCSIPKSQISFIDYFITGMFDAWD
AFVDLPELLQHLDNNFKYWKGLDERKLRSLRPPMESQ
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaattccatccggatcaactccaggtacttttagtgtttaccaaagaagataaccag
tgtaacggattctgtagggcatgcgaaaaggcagggtttaagtgtacagttactaaggag
gctcaggctgtccttgcctgtttcctggccaaacatcatgacatcatcatcatcgaccac
agaaacccccgacagctggatgcagaggcgctgtgcaggtctattcgatcatcaaaattt
tcagaaaacacagttattattggtgtagtacgcaggccggatagagaagagtcatctgta
atgcccctcattgctgctggcttcacaagaaggtatgtggagaaccccagcctcatggcc
tgttacaacgagctgctccagctggagtttggagaggtgcgatcgcagctgaaactcagg
acttgtaactcaatattcgctgcgttagagaaaagccaagaagcagttgaaatcacaagc
gaagaccacgtgatacagtatgcaaatcctgcatttgaaacaacaatgggctatgagtca
ggtgaattaatagggaagaagttagccgaagtgcctataaatgaaaaaaaggccgatttg
ctcgatactataaattcatacatcaggatgggcaaggagtggcaaggaatttgctatgcc
aaaaacggagataatgtacaacaaaatgtgaagataatacctgtcattggacagggagga
agaattagacactatgtgtccattatcagagtgtgcagtggcaacaacaaggccgagaaa
atagccgaatgtgttcagtctgacagactcacagataatcagtcaggcaaacataaagac
aagagaaaaagctcactagacgtcagagctgttggccatcgcgcgagcgaagtggccagc
cagagacgacactcctccatggcccggatacactccatgaccatcgaggcgcccatcacc
aaggtaatcaacatcatcaatgctgcccaggaaaacagtcccatgcctgtgacagaagcc
ttagaccgtgtgctggaaattctcagaaccactgagttatactcaccgcagttcggtgct
aaggacgatgaccctcatgccagtgacctcgtcgggggcctaatgtccgatggtttacga
agactatctgggaatgaatatgctctttcaacaaaaaactttcaacagattgcgagcaat
atagtcactcccatctcccttcacgacgtcccaccgcggatagctcaggccatagaaaac
gaggactactgggactttgatatttttgaactggaggccgccactcagaacaggccttta
atttatcttggtctcaaaatctttgctcgctttggaatctgtgaactcttaaactgctcc
gaggcaacactgagaacgtggttccagctcatcgaagccaattaccattcctctaacccg
taccacaactccacgcattctgccgacgtgcttcacgccaccgcctacttcctctgcaga
gagaggataaagcaaactctagatcccgtcgacgaggccgctgccctcattgcagccacc
attcatgacgtggaccaccccgggagaaccaactccttcctgtgtaacgctggaagcgag
ctggccattctgtacaatgacactgctgtgctggagagccatcatgcggccctggccttc
cagctgaccatcagagatgacaaatgcaatatcttcaagaacatggagaggaatgactac
cggacgctgcgccaggctatcattgacatggtcttggccacagagatgacaaagcatttc
gagcacgtcaacaagtttgtcaacagcgtcaacaagcccttggcagcactggaagcaaat
gaggaaacagatgaagagcaagcagccataaacaccgtgctcaggacgccggagaaccgg
actctgatcaagcgcatgctgattaagtgcgcggacgtgtccaacccctgccgaccgctg
gagcagagcatcgagtgggccgcccgcatctcggaggagtacttttcccagaccgatgaa
gagaagcggcaggacttacctgtggtgatgcctgtgtttgacagaaacacctgcagcatt
cccaagtctcagatctcgttcattgactacttcatcacaggcatgttcgatgcttgggac
gccttcgtggacctgccggagttgctgcagcatctcgacaacaacttcaaatactggaaa
ggactggacgagaggaagctgaggagcctccgaccaccgatggaatcccagtga
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