Pteropus giganteus (Indian flying fox): 120599285 Help Entry 120599285         CDS       T07511                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism pgig  Pteropus giganteus (Indian flying fox) Pathway pgig04010   MAPK signaling pathway pgig04014   Ras signaling pathway pgig04015   Rap1 signaling pathway pgig04022   cGMP-PKG signaling pathway pgig04066   HIF-1 signaling pathway pgig04068   FoxO signaling pathway pgig04072   Phospholipase D signaling pathway pgig04150   mTOR signaling pathway pgig04151   PI3K-Akt signaling pathway pgig04152   AMPK signaling pathway pgig04211   Longevity regulating pathway pgig04213   Longevity regulating pathway - multiple species pgig04520   Adherens junction pgig04910   Insulin signaling pathway pgig04913   Ovarian steroidogenesis pgig04923   Regulation of lipolysis in adipocytes pgig04930   Type II diabetes mellitus pgig04931   Insulin resistance pgig04932   Non-alcoholic fatty liver disease pgig04960   Aldosterone-regulated sodium reabsorption pgig05010   Alzheimer disease pgig05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:pgig00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     120599285 (INSR)    04014 Ras signaling pathway     120599285 (INSR)    04015 Rap1 signaling pathway     120599285 (INSR)    04066 HIF-1 signaling pathway     120599285 (INSR)    04068 FoxO signaling pathway     120599285 (INSR)    04072 Phospholipase D signaling pathway     120599285 (INSR)    04022 cGMP-PKG signaling pathway     120599285 (INSR)    04151 PI3K-Akt signaling pathway     120599285 (INSR)    04152 AMPK signaling pathway     120599285 (INSR)    04150 mTOR signaling pathway     120599285 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     120599285 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     120599285 (INSR)    04923 Regulation of lipolysis in adipocytes     120599285 (INSR)    04913 Ovarian steroidogenesis     120599285 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     120599285 (INSR)   09149 Aging    04211 Longevity regulating pathway     120599285 (INSR)    04213 Longevity regulating pathway - multiple species     120599285 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     120599285 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     120599285 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     120599285 (INSR)    04932 Non-alcoholic fatty liver disease     120599285 (INSR)    04931 Insulin resistance     120599285 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pgig01001]     120599285 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:pgig04090]     120599285 (INSR) Enzymes [BR:pgig01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      120599285 (INSR) Protein kinases [BR:pgig01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    120599285 (INSR) CD molecules [BR:pgig04090]  Proteins   120599285 (INSR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Kinase-like DUF4476 Motif Other DBs NCBI-GeneID:  120599285 NCBI-ProteinID:  XP_039714206 LinkDB All DBs Position Unknown AA seq 1378 aa AA seqDB search MGAAGGRGLAAAPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL GNCSEPGDPTKCTACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCLHLHNKCKNSRRQG CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC TVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLAFFRKLRLIRGDTL EVGNYSFYALDNQNLRQLWDWSKHHLTISQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSNIRTSFDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQSHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPSESEGSQKHNQSEYDDAAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRKSSAGPGAEDSRPSRKRRALGDVENVTTVAPTAPSF PNTSWTSVPTSLEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYV SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCV SRRHFALERGCRLRGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG PLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR EKITLLRELGQGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKG FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMVQMA AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV RWMAPESLKDGVFTASSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN CPERLTELMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME FEDMESVPLDRSSHSQREEDGGSTLGLKRNYEDHVPYTHMNGGKKNGRVLTLPRSSPS NT seq 4137 nt NT seq  +upstreamnt  +downstreamnt atgggcgctgcgggcgggcggggcttggccgcggcgccgctgctggtggccgtggccgcg ctgctggtgggcgccgccggccatctgtaccccggagaggtgtgtcccggcatggatatc cggaacaacctcacgaggctgcacgagctggccaactgctcggtcatcgaaggacatttg cagatactgttgatgttcaaaacgaggcctgaggacttccgagacctcagtttccccaaa ctcatcatgatcactgattacttgctgctgttccgggtctatgggctggagagcctgaag gacctgttccccaacctcacggtcatccggggctcccgtctcttcttcaactacgcgctg gtcatcttcgagatggttcacctgaaggagcttggcctctacagcctgatgaacattacc cggggctctgtccgcattgagaagaataatgagctctgttacctggccaccatcgactgg tcacgcatcttggattcggtggaggataattacatcgtgctgaacaaggacgacaacgag gagtgtggggacatctgtccaggcactgcgaagggcaagaccaactgccctgccaccgtc atcaacgggcagtttgtggagcggtgttggactcacagccattgccagaaagtctgcccg accatctgtaaatcgcacggctgcaccgccgaaggcctctgctgccacagcgagtgcctg ggcaactgctccgagcccggtgaccccaccaagtgcacggcctgccgcaacttctacctg gacggccggtgtgtggagacctgcccgcccccatactaccacttccaagactggcgttgt gtgaacttcagcttctgcctgcacctgcacaacaaatgcaagaactctcggaggcagggc tgtcaccagtatgtcattcacaataataagtgcatccctgaatgtccctccggatacacg atgaattccagcaacctgatgtgtactccgtgtctaggcccttgtcccaaggtctgtcac ctcctggaaggagagaagaccatcgactcggtgacatccgcccaggagctccgaggctgc accgtcatcaatgggagccttatcatcaacattcgagggggcaacaatctggcagctgag ctagaggccaacctcggcctcattgaagaaatttcagggtatctgaaaatccgccgttcc tacgccctcgtgtctcttgccttcttccggaagctacgtctgattcggggggataccttg gaagtcgggaactactctttctatgccttggacaaccagaacctgaggcagctgtgggac tggagcaaacaccacctcaccatctctcaggggaaactcttcttccactataatcccaaa ctctgcttgtcggaaattcacaagatggaggaagtttcaggaaccaaggggcgccaggag aggaatgacatcgccctgaagaccaatggggaccaggcatcctgtgaaaatgaattactt aaattttctaacattcggacgtcttttgacaagatcttgctgaaatgggagccgtactgg ccccccgacttccgagacctcctaggcttcatgctgttctacaaagaggccccttatcag aatgtgacagagttcgatgggcaggatgcatgcggctccaacagctggacggtggtggac attgacccacctttgaggtccaacgaccctaagtcacagagccaccccgggtggctgatg cggggtctgaagccgtggacccagtatgccatcttcgtcaagaccttggtcaccttttct gatgaacgtcgcacatatggggccaagagcgacatcatctatgtccagacagatgccacc aatccttctgtccccctggaccccatctcggtttccaactcctcatcccagatcatcctg aagtggaagcctccttctgaccccaacggcaacatcactcactacctggttttctgggag aggcaggcagaggacagtgagctgtacgagctggattattgcctcaaagggctgaagctg ccctcccggacctggtctccgccatcggagtcggagggttcccagaagcacaaccagagt gagtacgatgatgccgccggcgaatgctgctcctgccccaagaccgactctcagatcctg aaggagctggaggagtcgtcgttccggaagacattcgaggactacctgcacaatgtggtt tttgtccccagaaaatcctctgcaggccctggtgctgaggacagtaggccatcgaggaag cgcagggcccttggcgacgtggagaatgtgacgacggtcgcacccacggccccgagtttt cccaacacctcctggaccagcgtgcccacgagcttggaggagcaccggcccttcgagaaa gtggtgaacaaagagtcgctggtcatctccggcctgcgccacttcaccggctatcgcatc gagctgcaggcttgcaaccaggatgcgcccgaggaaaggtgcagtgtggcagcctacgtc agcgccaggaccatgccggaagccaaggcagatgacatcgttggccccgtgacccacgag atcttcgagaacaacgttgttcacttgatgtggcaggagccgaaggaacccaacggtctg attgtgctgtacgaagtgagctatcgacgatacggcgatgaggagctgcacctctgtgtc tctcgcaggcatttcgctctggagcggggctgcaggctgcgtgggctgcccccggggaat tacagcgtgcgagtgcgggccacctccctggcaggcaatggctcctggacggaagccacc tatttctacgtgacagactacctagacgtcccatcaaatattgcaaaaattatcatcggt cccctcatctttgtcttcctcttcagcgttgtgatcggaagtatttatctgttcctgagg aagaggcagccagatgggcccctgggaccgctgtatgcttcttcaaaccctgagtacctc agtgccagcgatgtgttcccctgttctgtgtatgtgccggacgagtgggaggtgcctcgg gagaagatcaccctcctgcgagagctggggcagggctccttcggcatggtgtatgagggc aacgccaaggacatcatcaagggcgaggcagagacccgggtggcggtgaagacggtcaac gagtcggccagcctgcgtgagcgcatcgagtttctcaacgaggcctcggtcatgaagggc ttcacctgccatcacgtggtccgcctcctgggggtggtgtccaaggggcagccgacactg gtggtgatggagctgatggcccacggagacctgaagagctaccttcgttccctgcggcct gaggctgagaacaaccctggccgccctcccccgaccctgcaagagatggtccagatggcg gcggagatcgcggacgggatggcgtacctgaacgccaagaagttcgtgcaccgggacctc gcagctcggaactgcatggttgcccatgatttcaccgtcaaaatcggagactttggaatg accagagacatctacgagacggattactaccggaaagggggcaagggcctgctccccgtg cggtggatggcgccggaatccctgaaggacggggtcttcactgcttcttcagacatgtgg tccttcggcgtggtcctctgggaaatcaccagcttggcagaacagccttaccaaggcctg tctaatgagcaggtgttgaaatttgtcatggatggagggtatctggatcaacccgacaat tgtccagagagactcaccgagctgatgcgcatgtgctggcagttcaaccccaagatgcgg ccgaccttcctggagatcgtcgacctgctcaaggacgacctgcaccccagctttccggaa gtttccttcttccacagtgaggagaacaaggcgcccgagagcgaggagttggagatggag tttgaggacatggagagcgtccccctggaccggtcctcacactctcagagggaagaggac ggagggtccacgctgggcctgaagcggaattacgaggatcacgtcccctacacccacatg aacgggggcaagaaaaatgggcgggtcctgactctgccacggtctagtccttcctaa

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