Pteropus giganteus (Indian flying fox): 120612453
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Entry
120612453 CDS
T07511
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pgig
Pteropus giganteus (Indian flying fox)
Pathway
pgig00230
Purine metabolism
pgig01100
Metabolic pathways
pgig04927
Cortisol synthesis and secretion
pgig04934
Cushing syndrome
pgig05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
120612453 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
120612453 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
120612453 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
120612453 (PDE8B)
Enzymes [BR:
pgig01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
120612453 (PDE8B)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
Motif
Other DBs
NCBI-GeneID:
120612453
NCBI-ProteinID:
XP_039730814
LinkDB
All DBs
Position
Unknown
AA seq
884 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPTAPLHGLFVQTDAADAVPQSRASG
PPGAVRIRRARAELGSGSSEGSAAPTTTTCRGRRRHCCSSAEAETQTSYSSVKVSSAEVR
IGPMRLTQDPIQVLLIFAKEDNQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIV
IDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQALGDHEEASVLPLLHAGFNRRFMEN
SSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFERM
MGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKI
TPVIGQGGKIRHFVSLKKLCCTTDHNKQIHKVHRDSGDNSQTESHSFRYKNRRKESIDVK
SISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEI
LRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITIN
DVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLRCSETTLRAWL
QVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPG
RTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAII
DMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPVGKNFPENQTLIKRMMIKCAD
VANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFI
TDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDN
NT seq
2655 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactca
gatgagtccaactcgccccggcagaccaccagcgtgtcgcagggccccacggccccgctg
cacggcctcttcgtccagaccgacgccgccgacgccgtcccccagagccgcgcgtcggga
ccccccggcgctgtccgcatccgccgggcccgcgctgagctgggcagcggcagcagcgag
ggctctgcagcccccaccacgaccacctgcaggggccggaggcgccactgctgcagcagt
gccgaggccgagacccagaccagctactccagcgtcaaggtttcttctgcggaggtacgc
attgggcccatgagactgacacaggatcctattcaggttttgctgatctttgcaaaggaa
gataatcagagtgatggattctggtgggcctgtgacagagctggttatagatgcaatatc
gctcgaactccggagtcagcccttgaatgctttctagataaacatcatgaaattattgta
attgatcacagacaaactcgaaattttgatgcagaagcagtgtgcaggtctatccgggcc
acaaatccctctgagcacacggtgatcctcgcagtggtttcacaagcattgggtgaccat
gaagaggcctcagttctccctcttctgcatgcaggcttcaacaggagatttatggagaat
agcagcataattgcttgctataatgaactgattcaaatagaacatggagaagttcgctca
cagttcaaattacgggcctgtaattcagtgtttacagcattagaccactgtcatgaagcc
atagaaataaccagcgatgaccatgtgattcagtatgtcaacccagctttcgaaaggatg
atgggctatcacaaaggtgaactcctggggaaagaactcgcagagctgcccaaaagcgat
aagaaccgggcagacctccttgacaccattaacacgtgcatcaagaagggcaaggagtgg
cagggggtttactatgccagacggaaatccggggacagcatccagcagcatgtgaagatc
accccagtgatcggccaaggagggaaaattaggcattttgtctccctcaagaaactgtgt
tgtaccactgaccataataagcagattcacaaggttcatcgtgattcaggagacaattct
cagacagagtctcattcattcagatacaagaacaggaggaaagagtccattgatgtgaaa
tcgatatcatctcgaggcagtgatgcaccgagcctacagaatcgtcgctatccatccatg
gcaaggatccactccatgaccatcgaggctcccatcacaaaggttataaatataatcaat
gcagcccaagaaaacagccccgtcacagtagcagaagccttggacagagttttagaaatt
ttacggaccacggaactgtactcccctcagctgggtaccaaagatgaagatcctcacacc
agtgatctcgttggaggcctgatgactgatggcttgagaaggttgtcaggaaatgagtat
gtgttcactaagaatgtgcaccagagtcacagtcaccttgcaatgccaataaccatcaat
gatgtccccccttgtattgctcaattacttgataatgaggaaagttgggagttcaacatc
tttgaactggaagctgttacacataaaaggccactggtctatctgggcttaaaggtcttt
tcccggtttggagtatgtgaatttttacgctgttctgaaactactcttcgggcctggctc
caagtgatcgaagccaactaccactcctccaatgcctaccacaactccacccatgctgcc
gacgtcttgcatgccactgccttcttcctggggaaggaaagagtgaagggaagcctcgat
cagctggatgaggtggcagcattgattgctgccacggtccatgacgtggaccacccggga
aggaccaactctttcctgtgcaatgcgggcagtgaacttgctgtgctttataatgacacc
gcggtcttggagagtcaccacacagccctggccttccagctgacggtcaaggacagcaag
tgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctattatt
gacatggttttagcaacggagatgacaaaacactttgaacatgtgaacaaatttgtgaac
agcatcaacaagccaatggcagctgagattgagggcagtgactgtgaatgcaaccctgtt
gggaagaactttcctgaaaaccaaactctgatcaagcgcatgatgattaagtgtgctgac
gtggccaacccgtgccgccccctggacctgtgcatcgaatgggctgggaggatctctgag
gagtactttgcacagactgatgaagagaagagacaggggctaccagtggtgatgccagtg
tttgaccggaatacctgtagcatccccaagtcccaaatctccttcattgactacttcata
acagacatgtttgatgcctgggatgcctttgcacatctgccagccctgatgcaacatttg
gccgataactacaaacactggaagacattagatgacctgaagtgcaaaagtctgaggctt
ccatctgacaactga
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