Phyllostomus hastatus (greater spear-nosed bat): 123811181
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Entry
123811181 CDS
T07912
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas04010
MAPK signaling pathway
phas04014
Ras signaling pathway
phas04015
Rap1 signaling pathway
phas04022
cGMP-PKG signaling pathway
phas04066
HIF-1 signaling pathway
phas04068
FoxO signaling pathway
phas04072
Phospholipase D signaling pathway
phas04150
mTOR signaling pathway
phas04151
PI3K-Akt signaling pathway
phas04152
AMPK signaling pathway
phas04211
Longevity regulating pathway
phas04213
Longevity regulating pathway - multiple species
phas04520
Adherens junction
phas04910
Insulin signaling pathway
phas04913
Ovarian steroidogenesis
phas04923
Regulation of lipolysis in adipocytes
phas04930
Type II diabetes mellitus
phas04931
Insulin resistance
phas04932
Non-alcoholic fatty liver disease
phas04960
Aldosterone-regulated sodium reabsorption
phas05010
Alzheimer disease
phas05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123811181 (INSR)
04014 Ras signaling pathway
123811181 (INSR)
04015 Rap1 signaling pathway
123811181 (INSR)
04066 HIF-1 signaling pathway
123811181 (INSR)
04068 FoxO signaling pathway
123811181 (INSR)
04072 Phospholipase D signaling pathway
123811181 (INSR)
04022 cGMP-PKG signaling pathway
123811181 (INSR)
04151 PI3K-Akt signaling pathway
123811181 (INSR)
04152 AMPK signaling pathway
123811181 (INSR)
04150 mTOR signaling pathway
123811181 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
123811181 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123811181 (INSR)
04923 Regulation of lipolysis in adipocytes
123811181 (INSR)
04913 Ovarian steroidogenesis
123811181 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
123811181 (INSR)
09149 Aging
04211 Longevity regulating pathway
123811181 (INSR)
04213 Longevity regulating pathway - multiple species
123811181 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123811181 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123811181 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
123811181 (INSR)
04932 Non-alcoholic fatty liver disease
123811181 (INSR)
04931 Insulin resistance
123811181 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phas01001
]
123811181 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
phas04090
]
123811181 (INSR)
Enzymes [BR:
phas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123811181 (INSR)
Protein kinases [BR:
phas01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
123811181 (INSR)
CD molecules [BR:
phas04090
]
Proteins
123811181 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Insulin_TMD
Kinase-like
DUF4476
B2
Motif
Other DBs
NCBI-GeneID:
123811181
NCBI-ProteinID:
XP_045683181
LinkDB
All DBs
Position
Unknown
AA seq
1377 aa
AA seq
DB search
MGAGGRRGTAATPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGAVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTVCKSHGCTAEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNTCKNSRRPG
CHQYVIHNNKCIPECPSGYTMNSSNLMCSPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TVINGSLIINIRGGNNLAAELESNLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGDTL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTTFDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPVRSNDPKSQSHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEDEESAGECCSCPKTDAQIL
KELEESSFRKTFEDYLHNVVFVPRKSSSGSDAEDSRPSRKRRALGDEGNVTTAVPTAPGF
PNTSSTSAPTNLEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIESNGVHLMWQEPKQPNGLIVLYEVSYRRYGDEELHQCVS
RRNFALERGCRLRGLLPGNYSVRVRATSLAGNGSWTETTYFYVTDYVVPSPDIAKIIIGP
LIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPRE
KITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGF
TCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLHEMIQMAA
EIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVR
WMSPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGHLDQPDNC
PDRLSELMRMCWQFNPKMRPTFLEIVDLLKDDLHPTFPEVSFFHSEENKAPESEELEMEC
EDMESVPLDRPSHFPREEVVGSPLGLKRSYEEHVPYTHMNGAKRNGRALTLPRSSPS
NT seq
4134 nt
NT seq
+upstream
nt +downstream
nt
atgggcgctgggggcagacgggggacggcggccacgccgttgcttgtggcggtggctgcg
ctgctggtgggcgccgcgggccacctgtatcccggagaggtatgtcccggcatggacatc
cggaacaacctcacgcggctgcatgagctggctaactgctcggtcatcgaaggacatttg
cagatactgttgatgttcaagacaaggcccgaggatttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctgttccgggtctacgggctggagagcctgaag
gacctgttccccaatctcacggtcatccggggttcccgtctgttcttcaactacgcgctg
gtcatctttgagatggttcacctgaaggagcttggcctctacagcctgatgaacatcacc
cggggggccgtccgcatcgagaagaacaatgagctctgctacctggccaccatcgactgg
tcgcgaatcctggattcagtggaggataattacattgtgctgaacaaagacgacaacgag
gaatgtggggacatctgtccaggcactgcgaagggcaagaccaactgccctgccacggtc
attaacgggcagtttgtcgagcggtgttggactcacagccactgccagaaagtctgcccg
accgtctgtaagtcacacggctgcactgccgagggcctctgctgccatagcgagtgcctg
ggcaactgctccgagcccgacgaccccaccaagtgtgtggcctgccgcaacttctacctg
gatggcaggtgtgtggagacctgtccgcctccatactatcacttccaagactggcgctgt
gtgaacttcagcttctgccaggacctgcacaacacatgcaagaactcgaggaggccaggc
tgccaccagtatgtcattcataataacaagtgcatccctgagtgtccctctggctacacg
atgaattccagcaacttgatgtgcagtccgtgtctgggcccctgtcctaaggtctgtcac
ctcctagaaggcgagaagaccattgactcagtgacgtctgcccaggagctccgaggctgc
actgtcatcaatgggagcctcatcatcaacattcgagggggcaacaacctggcagctgaa
ctagagtccaaccttggcctcattgaagaaatttcagggtatctgaaaatccgccgctcc
tatgctcttgtgtcactttccttctttcggaagttacgtctgattcggggggataccttg
gaaatcgggaactactctttctatgccttagacaaccagaacctaaggcagctatgggac
tggagcaagcacaaccttaccatcactcaggggaaactgttcttccactataatcccaaa
ctctgcttgtcagaaattcataaaatggaagaagtttcgggaacaaaggggcgccaggag
aggaatgacatcgccttgaagaccaatggggaccaggcatcctgtgaaaatgaattgctt
aaattttcttacattcggacaacttttgacaagatcttgctcaagtgggagccatactgg
ccccctgacttccgagaccttctggggttcatgctcttctacaaagaggccccttaccag
aatgtgacggagttcgatgggcaggatgcatgtggatccaacagctggacagtcgtggac
atcgacccgcctgtgaggtccaatgaccccaagtcccagagccaccccgggtggctcatg
cggggcctcaagccctggacccagtatgccatcttcgtgaagaccttggtcaccttttct
gatgagcgtcgcacatatggggccaagagcgacatcatctatgtccagacggatgccacc
aatccttccgtgcccctggatcccatctcggtttctaactcctcatcccagatcatcctc
aagtggaagcctccctctgaccccaacggcaacatcacacactacctggttttctgggag
aggcaggcagaggacagtgagctgtatgagttggattactgcctgaaagggctgaagctg
ccctcgcggacctggtccccaccgtttgagtcagagggctcccagaagcacaaccagagc
gaggacgaggagtctgctggggagtgctgctcctgcccgaagaccgatgctcagattctg
aaggagctggaggagtcctcgttccggaagacatttgaggattacctgcacaatgtggtt
tttgtccccagaaaatcctcttcagggtctgatgccgaggacagtaggccatcgaggaaa
cgcagggcccttggtgatgagggcaatgtgacgacggccgtgcccacagctcccggtttc
cccaatacctcctctaccagtgcacccacaaacttggaggagcaccggccctttgagaag
gtggttaacaaagagtcactggtcatctctggcctgcgccacttcactggctatcgcatc
gagctgcaggcttgcaaccaagatgcccccgaggaaagatgcagtgtggcagcctacgtc
agtgccaggactatgcccgaagccaaggcagatgacattgttggccccgtgacccatgaa
atcgagagcaatggcgttcatctgatgtggcaggagcccaagcagcccaacggtctgatc
gtgctatatgaagtaagttacaggagatacggcgatgaggagctgcaccagtgtgtctcc
cgcaggaattttgctctggagcggggctgcaggctgcgtgggctgctgccggggaattac
agtgtgcgagtacgggccacctccctggcgggcaatggctcctggacggaaaccacctat
ttttacgtgacagactatgtagtcccctcaccagatattgcaaaaattatcattggcccc
ctcatctttgtcttcctcttcagtgttgtgattgggagtatttacctgttcctgagaaag
aggcagccagatgggccgctgggaccgctatatgcttcttcaaaccctgagtacctcagt
gccagtgatgtgttcccatgttctgtttatgtgccggacgaatgggaggtgcctcgggag
aagattaccctgttacgggagctggggcagggctccttcggcatggtgtacgagggcaac
gccagggacatcatcaagggcgaggcagagacccgagtggcggtgaagacagtcaacgag
tcagccagcctgcgggagcggatcgagtttctcaacgaggcctcagtaatgaaaggcttc
acctgccatcatgtggtccgtctcctgggggtggtgtccaagggccagccgacgctggtg
gtgatggagttgatggctcatggagacctgaagagctacctccgttccctgcggcctgag
gctgagaataatcccggccgccctccccccaccctgcatgagatgattcagatggcagct
gagattgcagacgggatggcctacctgaatgcgaagaagtttgtgcaccgggaccttgca
gctcgaaactgcatggtcgcccatgatttcactgtcaaaattggagactttgggatgacc
agagacatctatgaaacggactattaccggaaaggcggcaaaggcctactccccgtgcgg
tggatgtcgccagagtccctgaaagacggggtcttcaccacctcctctgacatgtggtcc
tttggtgtggtcctctgggaaatcaccagcttggcagaacagccataccaaggcctctcc
aatgagcaggtgttgaaatttgtcatggatggaggacatctggatcagcctgacaattgt
ccagatagactcagcgaactgatgcgcatgtgttggcagttcaaccccaagatgaggccg
accttcctagagatcgttgacctgcttaaggatgacctgcaccccacctttccagaagtt
tccttctttcacagcgaggagaacaaggcacctgagagcgaggaattggagatggagtgt
gaggacatggagagcgtgcccctggaccggccctcacacttcccgagggaggaggtggtg
gggtcccccctgggcctcaagcgaagttacgaggagcacgtcccctacacccacatgaac
ggggccaagagaaatgggcgggccctgactctgccgaggtccagcccttcctaa
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