Phyllostomus hastatus (greater spear-nosed bat): 123830010
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Entry
123830010 CDS
T07912
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00010
Glycolysis / Gluconeogenesis
phas00020
Citrate cycle (TCA cycle)
phas00620
Pyruvate metabolism
phas00785
Lipoic acid metabolism
phas01100
Metabolic pathways
phas01200
Carbon metabolism
phas01210
2-Oxocarboxylic acid metabolism
phas04066
HIF-1 signaling pathway
phas04922
Glucagon signaling pathway
phas05230
Central carbon metabolism in cancer
phas05415
Diabetic cardiomyopathy
Module
phas_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
123830010 (PDHA1)
00020 Citrate cycle (TCA cycle)
123830010 (PDHA1)
00620 Pyruvate metabolism
123830010 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
123830010 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
123830010 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
123830010 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
123830010 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123830010 (PDHA1)
Enzymes [BR:
phas01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
123830010 (PDHA1)
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Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
123830010
NCBI-ProteinID:
XP_045711901
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYKMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTYTRGLSVREILAELTGRRGGCAKGKGGSMHMYARNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDVLCVREATKFAAAHCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSNDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtcgggcgctgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaag
tgtgatcttcaccggctggaggagggcccccctgtcacaacggtgctcaccagggaggat
gggctcaaatactacaagatgatgcagactgttcgccgaatggagttaaaggccgatcag
ctgtacaaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaagctggcataaatcccacagaccatctgatcaccgcctaccgggct
catggcttcacctatactcgtgggctttctgtgcgagaaattctcgcagagcttacagga
cgaagaggaggttgtgctaaaggaaaaggaggatcaatgcatatgtatgccagaaatttc
tatgggggcaatggcatcgttggagctcaggtgcccctgggagctgggattgctctggcc
tgcaagtataatgggaaagacgaggtctgtttgaccttatatggtgatggagctgctaat
cagggtcagatattcgaagcttataatatggcagctttgtggaaattaccttgtattttc
atctgtgaaaataaccgctatggaatggggacatctgttgagagagcagcagccagcact
gattactacaagagaggcgacttcattcctgggctgagggtagatggaatggatgtcctg
tgtgtccgggaggcaacaaagtttgcagcggcccattgtagatctggaaaggggcccata
ctgatggagctgcagacctaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagcaagagtgaccctatcatgcttctc
aaggatagaatggtgaacagcaaccttgccagtgttgaggaattaaaggaaattgacgtt
gaagtgaggaaagaaattgaggatgccgcccaatttgcaacagctgatcctgaaccacct
ttggaagaactaggctatcacatctactccaatgatccaccttttgaagttcgcggtgca
aatcagtggattaagtttaagtctgtcagttaa
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