Pseudonocardia sp. HH130630-07: AFB00_14370
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Entry
AFB00_14370 CDS
T04486
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
phh
Pseudonocardia sp. HH130630-07
Pathway
phh00860
Porphyrin metabolism
phh01100
Metabolic pathways
phh01110
Biosynthesis of secondary metabolites
phh01120
Microbial metabolism in diverse environments
phh01240
Biosynthesis of cofactors
Module
phh_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
phh_M00925
Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide
phh_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
phh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
AFB00_14370
Enzymes [BR:
phh01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
AFB00_14370
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
AFB00_14370
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GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ANY07270
UniProt:
A0A1B1ZNH4
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Position
2960480..2962021
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AA seq
513 aa
AA seq
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MTGPANTSGRIAFVGSGPGDPALLTVRARDVLAGSPLVITDPDVPEGILALAADGAEVRP
AVGQPADIASDLLAESAQGRSVARLVSGDPLTNDAVVAEAMAVSASGSLFDVVPGVPAST
AVPAYAGVALGSAHVEADVRAGVDWAALAASPGPVVLHATGALLADVATGLSAQGVPAET
AVAITAGGTTSTQRTISSSVGKLASDGGDLEGALVLTVGDAAGRRGELSWWESRALYGWR
VLVPRTKDQAGVMSERLRMHGAIPEEVPTIAVEPPRSPAQMERSVKGLVDGRYQWVVFTS
TNAVKAVWEKFAEFGLDARAFSGVKIACVGRSTAEKVREFGIEPELVPDIDEAQSSTSEG
LLEIFPPHDDVLDPVDRVLLPRADIATETLSAGLQERGWEVDDVTAYRTVRAAPPPAPIR
EAIKTGGFDAVCFTSSSTVRNLVGIAGKPHARTLVACIGPATAETAREFGLRVDVQPEES
RVPTLVDALASHTAKLRAEGNLPPPKKVKARRR
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgacaggacctgccaacacctcggggcggatcgccttcgtgggcagcggaccgggtgac
ccggcactgctcacggtgcgcgcccgggacgtgctcgccggctcgccgctggtgatcacc
gacccggacgtgccggagggcatcctcgccctggccgccgacggcgccgaggtccgcccg
gccgtcggtcagcccgccgacatcgcgagcgacctgctcgccgagtccgcacagggccgg
tcggtggcccgcctggtctcgggtgacccgctgaccaacgacgccgtcgtcgcggaggcg
atggccgtctccgcgtcgggctcgctgttcgacgtcgtgccgggtgtgcccgcctccacc
gccgtcccggcctatgccggggtcgcgctgggctcggcgcacgtcgaggccgacgtccgg
gccggcgtcgactgggccgcgctggccgcctcgcccgggccggtcgtgctgcacgccacc
ggcgcgctgctcgccgacgtcgcgaccgggctgtccgcgcagggcgtgcccgccgagacc
gcggtcgcgatcaccgccggtggcaccacctcgacccagcggacgatctcgtcgtcggtg
ggcaagctcgcctccgacgggggcgacctggagggcgcgctcgtcctgaccgtcggtgac
gccgccggtcgccgcggcgagctgtcctggtgggagtcgcgcgcgctctacggctggcgg
gtgctggtcccgcggaccaaggaccaggccggcgtgatgagcgagcggctgcggatgcac
ggcgccatcccggaggaggtgccgacgatcgccgtcgagccgccccggtccccggcgcag
atggagcgttcggtcaagggcctggtcgacggccgctaccagtgggtcgtcttcacctcg
accaacgcggtcaaggccgtgtgggagaagttcgccgagttcggcctggacgccagggcg
ttctccggtgtgaagatcgcctgcgtgggccggtcgaccgcggagaaggtgcgcgagttc
ggcatcgagccggagctggtcccggacatcgacgaggcgcagtcctcgacgtcggagggg
ctgctggagatcttcccgccgcacgacgacgtgctcgacccggtggaccgggtgctgctc
ccgcgcgccgacatcgccaccgagacgctgtccgccgggttgcaggagcgtggctgggag
gtcgacgacgtgacggcctaccggaccgtccgcgccgccccgccgcccgcgccgatccgt
gaggcgatcaagaccggcgggttcgacgcggtgtgcttcacctcgtcgtcgaccgtgcgg
aacctggtcggcatcgccggcaagccgcacgcccgcaccctggtcgcctgcatcggcccg
gccaccgcggagaccgcccgcgagttcggcctgcgggtggacgtgcagcccgaggagtcc
cgcgtcccgaccctggtcgacgcactggcgagccacaccgccaagcttcgcgccgagggc
aacctgcccccgccgaagaaggtcaaggcccgccgccgctga
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