Peromyscus leucopus (white-footed mouse): 114695795
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Entry
114695795 CDS
T07241
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu00010
Glycolysis / Gluconeogenesis
pleu00020
Citrate cycle (TCA cycle)
pleu00620
Pyruvate metabolism
pleu00785
Lipoic acid metabolism
pleu01100
Metabolic pathways
pleu01200
Carbon metabolism
pleu01210
2-Oxocarboxylic acid metabolism
pleu04066
HIF-1 signaling pathway
pleu04922
Glucagon signaling pathway
pleu05230
Central carbon metabolism in cancer
pleu05415
Diabetic cardiomyopathy
Module
pleu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
114695795 (Pdha1)
00020 Citrate cycle (TCA cycle)
114695795 (Pdha1)
00620 Pyruvate metabolism
114695795 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
114695795 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
114695795 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
114695795 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
114695795 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
114695795 (Pdha1)
Enzymes [BR:
pleu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
114695795 (Pdha1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
114695795
NCBI-ProteinID:
XP_028729088
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All DBs
Position
X:33853751..33870207
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtgtcccgcgtgttggcaggcgctgcgcagaagccggca
agcagagtgctagtagcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcaccacagtgctcaccagagaggat
ggcctcaagtactaccggatgatgcagactgtgcggcgaatggagctcaaggcagatcag
ctgtataaacagaagattattcgtggtttctgtcacttgtgtgacgggcaggaagcctgc
tgtgtgggcctggaggccggcataaaccccaccgaccacctcatcacagcctatcgagcg
catggcttcaccttcactcgaggcctgtctgtccgagcaattcttgcagagctaacagga
agaagaggaggttgtgctaaagggaaaggcggatcgatgcacatgtacgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgcccctgggagcagggattgctctggcc
tgcaagtataatggaaaagatgaggtctgtttgactttatatggtgatggtgctgctaat
cagggtcaaatatttgaagcttacaatatggcagcattgtggaaattaccttgtattttc
atctgtgaaaataaccgctatggcatggggacgtctgtcgagagagcagcggccagcaca
gattactacaaaagaggagattttattcctggactgagggtagatggaatggatatcttg
tgtgtccgagaggcaacaaagtttgcagctgcctattgtaggtctggtaaggggcccatc
ctgatggaactacagacttatcgttaccatggacatagtatgagtgaccctggagtcagt
taccgcactcgagaagaaatccaggaagtaagaagtaagagcgaccctattatgcttctt
aaggataggatggtgaacagcaatcttgcgagtgttgaagaattaaaggagattgatgtg
gaagtgagaaaagaaatcgaggatgctgcccagtttgctacagctgatccagagccaccc
ttggaggaactaggctatcacatctacagcagtgatcctccctttgaagtgcgtggtgcc
aaccagtggatcaagttcaagtcagtcagttaa
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