Perognathus longimembris pacificus (Pacific pocket mouse): 125343333
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Entry
125343333 CDS
T08928
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop00010
Glycolysis / Gluconeogenesis
plop00020
Citrate cycle (TCA cycle)
plop00620
Pyruvate metabolism
plop00785
Lipoic acid metabolism
plop01100
Metabolic pathways
plop01200
Carbon metabolism
plop01210
2-Oxocarboxylic acid metabolism
plop04066
HIF-1 signaling pathway
plop04922
Glucagon signaling pathway
plop05230
Central carbon metabolism in cancer
plop05415
Diabetic cardiomyopathy
Module
plop_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
125343333 (Pdha1)
00020 Citrate cycle (TCA cycle)
125343333 (Pdha1)
00620 Pyruvate metabolism
125343333 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
125343333 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
125343333 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
125343333 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
125343333 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
125343333 (Pdha1)
Enzymes [BR:
plop01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
125343333 (Pdha1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
125343333
NCBI-ProteinID:
XP_048191632
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All DBs
Position
X:complement(102116033..102129334)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLLGVAQKPATRVLVASRNFANDATFEIKKCDLHRLDEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgttgggcgttgcccagaagccggca
accagagtgctagtggcatcacgtaattttgcgaatgatgctacttttgaaattaagaag
tgtgaccttcaccggctggatgaaggccctcccgttacaactgtgctcaccagagaggat
gggctcaaatactataggatgatgcagactgtgcgccggatggagttaaaagctgatcag
ctgtataaacagaaaattattcgtggtttctgtcacctatgtgatggtcaggaagcttgc
tgtgtgggcctcgaggctggcataaaccctacagaccatctcatcacagcctaccgggct
catggcttcaccttcactcggggtctttctgttcgtgaaattctcgcagagctaacagga
cgaagaggaggttgtgctaaagggaaaggaggatctatgcacatgtatgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtacccctgggagctgggatcgccctggcc
tgtaagtataatggaaaagatgaagtctgtttgacactatatggtgatggcgctgctaat
cagggtcagatatttgaagcctacaatatggcagcattatggaaattaccgtgtattttc
atctgtgagaataaccgctatggaatgggaacgtctgttgagagagcagcggccagtact
gactactacaagagaggagactttatccctgggctgagggtagatggaatggatatcttg
tgtgtccgagaggccacaaagtttgcagccgcctattgtagatctgggaagggacctatc
ctgatggagctgcagacttaccgttaccatggacacagcatgagtgaccctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtcaacagcaatctggccagtgtcgaagaactaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgccgcccagtttgccaccgctgatcctgagccgcct
ttggaggagctcggctatcacatctacagcagcgatccaccgtttgaagtgcgtggggcc
aaccagtggatcaagtttaagtcagtcagttaa
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